Acanthosis nigricans

Normally, the Pancreas controls the body’s blood glucose levels by the secretion of insulin and glucagon. The endocrine part of the pancreas is made up of cells called Islet of Langerhans. The two main parts of the Islet of Langerhans are the Alpha cells, which secrete glucagon and the Beta cells which secrete insulin. After a meal, the blood glucose level will rise, the pancreas reacts to this situation by secreting insulin, which will transport the excess glucose from the blood to target cells

Many people across the world suffer from dark skin on their underarms, which is sometimes referred to as acanthosis nigricans, a medical condition that results in darkening of the skin. Dark underarms can affect people of all ages and skin types, and many people find it embarrassing. Although dark underarms can be caused by a variety of different things, most often, this skin condition is caused by a resistance to insulin, which eventually leads to diabetes. It can also be the result of hormonal

PCOD: The Rising Issue Polycystic Ovary Syndrome affects an estimated 5-10 percent of women of childbearing age and it is a leading cause of infertility. It is the most common endocrinopathy among reproductive age women and as many as 30 percent of women have some characteristics of the syndrome. PCOS is generally considered a syndrome rather than a disease (though it is sometimes called Polycystic Ovary Disease) because it manifests itself through a group of signs and symptoms that can occur in

Pediatric type 2 diabetes: Emergence and Preventive Measures Type 2 diabetes, diabetes mellitus, is a chronic disease characterized by high blood glucose levels in the bloodstream; usually caused by the inability of the pancreas to produce insulin or the inability of the body to use it efficiently. This condition occurs mostly in adults, but it can also appear in children, teenagers, and young adults. Considered one of the fastest growing health problems in the United States, diabetes now affects

Carla Rodriguez MED 2056 Diabetes Mellitus Instructor Anglo March 11, 2015 Pathophysiology Diabetes mellitus is an autoimmune disease and affects the body’s metabolism of carbohydrates. There are varying types of diabetes but patients are predominantly diagnosed with type 1 or 2. Type 1 is an insulin dependent diabetes mellitus and type 2 is a non-insulin dependent diabetes mellitus. Patients are tested for diabetes by undergoing blood sugar tests or urinalysis. Typical symptoms are

Paraneoplastic Syndromes Paraneoplastic syndromes are rare disorders triggered by a person's immune system in response to a cancerous tumor. Paraneoplastic syndromes can affect many areas of the body systems, including the nervous system, hormone (endocrine) system, skin (dermatologic) system, blood (hematologic) system, and joints (rheumatologic) system. CAUSES The exact cause of these syndromes is not known. However, these syndromes are believed to occur when the tumor cells of the cancer cause

part of the legs. Insulin resistance in type 2 diabetes can cause darkened areas of skin to appear in the armpits and the folds of the neck. Diabetes other skin related symptoms may include atherosclerosis, Sclerodermadiabeticorum, Vitiligo, Acanthosis nigricans, Necrobiosis lipoidica diabeticorum, Diabetic dermopathy, Digital sclerosis, Eruptive xanthomatosis, Rashes and bumps, Diabetic blisters, Disseminated granuloma

As of 2014 an estimated 30 million people in the United States alone have diabetes; out of this diabetic population about 95% have type 2 diabetes, also known as adult-onset diabetes ("Infographics," 2014). Unlike type 1 diabetes, type 2 diabetes may be preventable. Type 2 diabetes isn’t only seen in adults, this disease is becoming more relevant in children as child obesity increases (American Academy of Pediatrics, 2014, p. [Page #1]). If not detected or controlled many complications can occur

treatment of long-term PCOS complications65 Clinical assessment Therapeutic approaches Metabolic risk Screening for impaired glucose tolerance and T2DM with 75 g OGTT in PCOS women with: – age >40 years – BMI >30 – classic phenotype – presence of acanthosis nigricans – personal and/or family history of T2DM BMI and waist circumference at every visit: – waist circumference> 80 cm – abdominal obesity Periodic reassessment with OGTT Lifestyle change programs (hypocaloric diet and physical exercise) represent

One of the prospects of research on high-risk population is the ability to recognize the disease and its outcomes, is to identify and implement of evidence-based intervention that will reverse or slow the progress of the negative outcomes of the disease (Ricci-Cabello, et al. 2013). Type 2 diabetes mellitus (T2DM) is a progressive and protracted disease related with substantial morbidity and mortality. African Americans (AA) adults have the highest occurrence of T2DM due to factors such as obesity