Carla Rodriguez
MED 2056
Diabetes Mellitus
Instructor Anglo
March 11, 2015
Pathophysiology
Diabetes mellitus is an autoimmune disease and affects the body’s metabolism of carbohydrates. There are varying types of diabetes but patients are predominantly diagnosed with type 1 or 2. Type 1 is an insulin dependent diabetes mellitus and type 2 is a non-insulin dependent diabetes mellitus. Patients are tested for diabetes by undergoing blood sugar tests or urinalysis. Typical symptoms are increased thirst, frequent urination, slowed healing, weight loss, excessive hunger, blurred vision and integument issues. Though this condition varies in severity, most patients can be treated with medications, by balancing their diets, and monitoring their blood sugar levels.
Patients with type 1 diabetes are believed to have acquired it through genetic disposition or an autoimmune abnormality caused by an environmental trigger. Essentially, the body’s pancreatic beta cells are destroyed, which in turn, inhibits the pancreas from either producing or secreting insulin. This caused a disarraying effect to all body systems. The cause of type 2 diabetes is said to be from an “imbalance between insulin sensitivity and insulin secretion” (Ralph A. DeFronzo). The pancreas is not producing adequate levels of insulin, seizing production of insulin or the insulin that is produced isn’t being used well (Kullman, 2006, p.146). This is an issue because sugar stays sedentary in the
Type II Diabetes, also known as diabetes mellitus, is also called non-insulin-dependent diabetes or aadult onset diabetes. It is a medical disorder that, due to a number of factors codependent with the modern world, is characterized by higher than normal blood glucose levels that play havoc with insulin deficiency and resistance. Insulin resistance means that cells do not respond appropriately when there is free insulin in the blood system. Essentially, they body is reacting to an improper balance of sugars and insulin. Because obesity is often present, research suggests that even thought the mechanisms controling glucose and insulin are unclear, the adopose tissue likely
Type 2 Diabetes is a disease that is found in a variety of age groups around the world. This disease is growing at a rapid rate and it is impacting the health of this generation and future generations to come. Diabetes is a disease that impairs the body’s ability to produce or respond to the insulin hormone produced by the pancreas. The insulin allows for the glucose to be effectively used as energy throughout the body. Diabetes causes carbohydrates to be abnormally digested, which can raise blood glucose levels. This means that the glucose is not being taken up by the cells that need it. The cells cannot take up the excess glucose that has accumulated in the blood, so it is excreted through the urine. This can lead to problems with the kidneys, central nervous system, heart, and eyes because high blood glucose can damage the blood vessels of these organs. This diseased is managed by adopting a diet low in fat and high in fiber, increasing physical activity, losing excess weight, and not smoking. If this
Diabetes mellitus is a group of metabolic disorders characterized by inadequate insulin secretion by the pancreas or cellular destruction leading to an insulin deficiency. Depending on the cause of the insulin shortage, diabetes can be subcategorized into type I and type II. Type I diabetes (T1DM) is usually mediated by the destruction of b-cells in the pancreas resulting in decreased insulin production and secretion. Type II diabetes (T2DM) is the failure of these b-cells to secrete adequate amounts of insulin to compensate for insulin resistance and increased gluconeogenesis combined with an overall resistance to the insulin action (8., 1997). T2DM accounts
Insulin resistance is the first physiological change occurring in type two diabetes. In these type two diabetic patients, insulin is unable to move glucose into liver, kidney and muscle cells although insulin is able to attach properly to the cell surface receptors. In order to rectify this, most patients with type two diabetes start secreting normal to very high levels of insulin, which can initially overcome this resistance. After a while, the pancreas cannot keep up with this high insulin production and the cells become resistant to glucose intake. Persistent hyperglycemia or high blood glucose levels are not desirable since this causes damage to the beta cells of the pancreas that produces the insulin hormone. This damage to beta cells further hampers insulin synthesis and patients at this stage are categorized as full-blown diabetic. Such patients consistently show a hyperglycemia state even after hours of fasting ( Hinkle & Cheever,
Diabetes Mellitus (DM) or Type 2 Diabetes is seen as a metabolic disease that is categorized by abnormally high blood glucose or hyperglycemia. Diabetes Mellitus is also formerly known as noninsulin-dependent diabetes mellitus and is the most common form of diabetes that is seen. Insulin is a hormone that is supplied to the body that allows us to efficiently use glucose as fuel. When carbohydrates are broken down into sugars in the stomach glucose enters the blood circulation simulating the pancreas to release insulin in an appropriate amount to become used for energy. With diabetes mellitus the body does not properly make use of the insulin supplied for the body. This causes the pancreas to produced an extra amount if insulin which the body cannot keep up with, causing an imbalance to the blood glucose levels (American Diabetes Association, 2015). In the united states diabetes affects almost 29.1 million people, while the another 86 million people have pre-diabetes but do not know. It is also known as the 7th leading cause of death in the country in the recent years (MedicineNet.com, 2016). For a patient suffering from a chronic form of diabetes mellitus understanding how these mechanisms lead to the condition can be used as preventative measures. Potential consequences as well as the causes and clinical manifestations will ensure a better knowledge on the issue to monitor the condition.
Diabetes mellitus type 2 is an endocrine disorder that causes impaired use of carbohydrates while enhancing the use of proteins and lipids. This is called insulin resistance, in which the pancreas cannot make enough insulin to keep blood glucose levels normal, or the body is unable to use what is produced. The impairment causes blood glucose level to rise higher than normal. There is no cure for type 2 diabetes mellitus and it is life threatening when left untreated. Signs and symptoms of this disorder include vision changes, increased thirst, increased hunger, increased frequency of urination, stomach pain, nausea and vomiting, erectile dysfunction, and absences of mentruation. These can occur abruptly, or over a long period of time.
Type 1 diabetes is a chronic illness characterized by the body’s inability to produce insulin. Onset most often occurs in childhood, but the disease can also develop in adults in their late 30s and early 40s. The classic symptom of type 1 diabetes is: The need to urinate frequently, excessive drinking as a result of thirst, excessive hunger and abnormally large intake of solids by mouth. Unexplained weight loss, Other symptoms may include fatigue, nausea, and blurred vision. The onset of symptomatic disease may be sudden and is a classic sign of diabetes mellitus that is under poor control or not under treatment
Diabetes of any type can produce a variety of symptoms. The most common symptoms are increased thirst, increased urination, nausea, fatigue, slow healing cuts or sores, dry mouth, itchy skin, blurred vision, and unusual weight loss or gain. Type 1 diabetes is usually characterized as an autoimmune disorder and appears in previously healthy people of normal weights and who have good diets and exercise regularly. Type 2 diabetes is the most common type of diabetes and is usually considered a lifestyle diabetes, appearing in people who have poor diets, who are overweight, and who have
Diabetes has become a widespread epidemic, primarily because of the increasing prevalence and incidence of type 2 diabetes. Diabetes is an endocrine disease in which the body has either a shortage of insulin or a decrease ability to use insulin or both. Insulin is a hormone that allows glucose to enter the cells and be converted into energy. Diabetes can be characterized as a prevailing, incapacitating, and deadly disease. There are a number of risk factors that increase a person’s tendency toward developing type II diabetes. Modifiable risk factors include obesity, physical inactivity and poor dietary habits are just a few. The
Type 1 diabetes is an autoimmune disorder, in which the pancreas does not produce insulin. It usually begins in childhood or adolescence. In Type 1 diabetes, the body’s immune system destroys beta cells in the pancreas that produce insulin. Insulin is a hormone that converts sugar, starches, and food into energy. Without insulin, blood glucose levels become too high, which is known as hyperglycemia. To prevent hyperglycemia, people with Type 1 diabetes must take insulin daily to survive. Genetic and environmental factors affect the onset of Type 1 diabetes. [1] According to the American Diabetes Association, a predisposition to Type 1 diabetes is
Diabetes is the seventh leading cause of death in the U.S., according to the CDC. Type 2 diabetes is the most common form of diabetes (CDC, 2014). 90- 95% of the people with diabetes have Type 2 (CDC, 2014). Historically, type 2 diabetes has been diagnosed primarily in middle-aged adults (CDC, 2014). Today, however, adolescents and young adults are developing type 2 diabetes at an alarming rate. Unlike people with type 1 diabetes, the body produces insulin but either their pancreas does not make enough insulin or the body cannot use the insulin well enough. This is called insulin resistance. When there isn 't enough insulin or the insulin is not used as it should be, glucose can 't get into the body 's cells. When glucose
Type 2 diabetes is a chronic disorder in which the body does not properly respond to insulin well, thus allowing high concentrations of glucose to
Diabetes is one of the major health issues with which the America is battling today. Increasing incidents of diabetes have are reported in the United States in the past decade. Type 2 diabetes is the most common form of diabetes. In type 2 diabetes, the body does not use insulin properly. At first, the pancreas makes extra insulin to make up for it. However, over time the pancreas is not able to keep up and cannot make enough insulin to keep the blood glucose levels normal.
As previously stated, there is Type 1 and Type 2 diabetes. Due to the differentiation, the etiology of diabetes is divergent. Being insulin-dependent, Type 1 diabetes is brought about by the immune system eradicating beta cells, leading to the deficiency of insulin. In contrast, Type 2 diabetes has a basis that can often times be prevented to an extent (“Causes of Diabetes”, 2014).
Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the