Clostridium difficile

Clostridium difficile or otherwise known as C.diff. is a life threating infection that can cause a wide range of symptoms. Patients can experience anything from diarrhea to inflammation of the colon that can lead to death. In the past few years, Clostridium difficile infection rates have increased here in the United States causing great concern about the effectiveness of current treatments. For the past fifty years, the medical community has been investigating other areas for better treatment options

(2015) states that one of the worst attackers is a bacterium called Clostridium difficile (C. difficile) . As this bacterium grows out of control, it releases toxins that attack the lining of the intestines, which causes a condition called Clostridium difficile colitis. Although this bacterium is more rare than other intestinal bacteria, C. difficile is one of the most popular causes of infectious diarrhea in the U.S. C. difficile infection can range from causing minor discomfort to life-threatening

The difficulties of Clostridium difficile: Examining the risks of nosocomial bacteria Checking in to the hospital comes with a heavy price tag, and sometimes you get more than what you bargained for. As highly trained doctors, nurses, and staff traverse through the hospital, they carry with them microbial agents of disease. Although regarded as centers for treatment and prevention, hospitals are also known to harbor nosocomial, healthcare-associated, bacterial infections. These infections

Introduction Clostridium difficile is a gram positive, anaerobic, spore forming bacillus. In 1935 it was first described as member of the intestinal flora in healthy neonates [1] , and then in 1978 it was recognised as a cause of diarrhoea [2]. Today it is widely acknowledged as the leading cause of hospital-acquired diarrhoea. This organism can cause a variety of diseases, from mild diarrhoea to severe pseudomembranous colitis, and collectively these are known as C. difficile infections (CDIs)

vancomycin for Clostridium difficile Infection? Background: Clostridium difficile is a spore forming, anaerobic, toxin-producing, gram-positive bacillus that is the most common cause of nosocomial, antibiotic-associated diarrhea (15-25%).1,2,3 The pathogenesis of C. difficile-associated diarrhea (CDAD) is the result of broad spectrum antibiotics, such as clindamycin, flouroquinolones or ceftriaxone, which reduces the population of normal bowel flora and allowing for an overgrowth of C. difficile.1,2 The

Clostridium difficile is an obligate anaerobe, gram positive bacteria that has the ability to form spores. Clostridium difficile is the leading cause of nosocomial antibiotic associated diarrhea worldwide. C. difficile is an opportunist pathogen that utilizes many factors to infect and damage the host, often with overwhelming consequences. Symptoms range in severity from mild diarrhea to pseudomembranous colitis and toxic megacolon, the most severe form of disease, which often results in death

inciting nosocomial bacterial, Clostridium difficile has been rampant. It is important that inefficiencies in health-care be met with stringent efforts for prevention as they may lead to distressing financial, emotional, and medical repercussions. Introduction- New challenges from an established pathogen: Ample literature has been published to elucidate the pervasive nature of Clostridium difficile and its relationship with inadequate health-care practices. Clostridium difficile-associated disease: New

Clostridium difficile infection (CDI) is the most common cause of antibiotic associated diarrhea (AAD). Rapid diagnosis of CDI is essential to prevent hospital spread of infection. The aims were to determine the prevalence of CDI among cases of AAD in Zagazig University Hospitals, identify risk factors, and evaluate real-time polymerase chain reaction (PCR) and enzyme immunoassay (EIA), against toxigenic culture (TC). Stools were collected from 150 patients with AAD. They were tested for TC, toxin

Clostridium difficile is a gram positive bacterium responsible for over 10,000 deaths annually in the United States alone. C. difficile is an opportunistic pathogen that has progressively become antibiotic resistant in several strains. The bacterium strives in hosts currently taking antibiotics where there is no competition between commensal microbiota. Common known symptoms of C. difficile infections (CDIs) include diarrhea, fever, and toxic megacolon. Primary virulent factors of the bacterium currently

Clostridium difficile infection is a suprainfection cause by prolong use of antibiotics. Board spectrum antibiotic such as Penicillins, clindamycin, and cephalosporins are the antimicrobial drugs most commonly associated with C difficile colitis. According to Owens, in his research, C. difficile is primarily acquired in hospitals. Spread by spores, it can colonize a patient’s gut after helpful gut bacteria are killed by antibiotics. Its toxins can cause severe diarrhea and colitis, and it can be