Hemorrhagic

Literature Review: Cyclophosphamide Name of Drug Cyclophosphamide1 Proprietary Names Cyclophosphamide1,2, Cytoxan1 and Endoxana2 IUPAC Name 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide (scifinder) Structural Formula Stereoisomerism Cyclophosphamide has two stereoisomers, (S)-(-)- and (R)-(+)-cyclophosphamide enantiomers, due to the chiral phosphorus centre (Figure 2). The stereoisomerism of cyclophosphamide affects its anti-tumour properties, with the (S)-(-)

alarming rate. The monkeys, imported from the Philippines, were to be sold as laboratory animals. Twenty-nine of a shipment of one hundred died within a month. Dan Dalgard, the veterinarian who cared for the monkeys, feared they were dying from Simian Hemorrhagic Fever, a disease lethal to monkeys but harmless to humans. Dr. Dalgard decided to enlist the aid of the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) to help diagnose the case. On November 28th, Dr. Peter Jahlring

Emily Goetz Emerging Diseases Professor Kim O'Neill 10-17-2015 Should we be concerned about Ebola? Ebola is a rare but deadly virus that causes bleeding inside and outside the body. The disease, (also known as the Ebola virus), has a mortality rate of 90% (Nazario, 2014). As the virus spreads through the body, “it damages the immune system and organs” and it “causes levels of blood-clotting cells to drop” (Nazario, 2014). Causing severe, uncontrollable bleeding. However frighteningly deadly

A disease that has yet to be conquered” (Barrett & Higgs, 2007). Such a quaint, simplistic phrase that yet effectively describes the disease commonly known today as yellow fever. Over the course of history, the yellow fever virus (YFV) has decimated populations in various regions all across the globe. While the overall gross impact of yellow fever has declined over the years, the virus still poses a significant threat present day, especially to those in the developing world. The World Health Organization

Many people do not pay attention to cholesterol until the get high or low cholesterol. You'll see someone look at the calories, fat, sugars, but do people not know cholesterol is very important to have. When was the last time you talk about how high in cholesterol a food is? There are many reasons to why cholesterol is very important to your body. First of all what is cholesterol? Cholesterol is the type of fat found in your blood. You could have a high or low cholesterol. If your

toxin producing E. coli (STEC). Infection with non- O157 STEC strains have been associated with diarrhoea and dysentery in young calves (Sandhu and Gyles, 2002) and severe outbreaks of gastrointestinal illness in humans ranging from diarrhea and Hemorrhagic Colitis (HC) to the lifethreatening Hemolytic Uremic Syndrome (HUS) (Lynn et al., 2005). Sporadic cases and large outbreaks in humans are associated with contact with STEC positive animals or environment (Caprioli et al., 2005). The pathogenicity

Background There are various categories of human environmental hazards: chemical, biological, physical and psychosocial/cultural. Each, in its own way, contributes to an overall situations or threats that affect both the environment and human life. Sometimes a fifth category is included, mechanical, which include energy plants, factories, etc. Chemical Hazards Chemicals are both naturally occurring and man-made. From the environment, exposure to chemical agents in our air, water, food and soil,

vasculitis range over a wide variety: Superficial small vessel involvement producinges palpable purpura, petechiae, or urticaria Deeper involvement of dermal or subcutaneous muscular vessels manifesting as nodular red areas, livedo racemosa, hemorrhagic

underwent clinical observations in two different hospitals. After London, Rush went to Paris, where he extended and completed his clinical training. In 1769, he traveled back to America and began his career as a physician. Yellow fever, a viral hemorrhagic fever, was one of the deadliest diseases to hit North America. It is transmitted by female mosquitoes of the Aedes aegypti species. When a person is infected with the disease, the symptoms of high fever, nausea, vomiting, yellowing of the skin

noted in his diary that President Roosevelt “appeared to be have had signs of ‘hardening of the arteries disease’ and had a few months to live.” Subsequent events demonstrated the truth of his diagnosis. President Roosevelt ultimately had a fatal hemorrhagic stroke 2 months later, and his death brought hypertension’s potential as a deadly malady to the lime light (Mahmood, Levy, Vasan, Wang, 2014). Three years after Roosevelt’s death, the pivotal National Heart Act was signed into law by President Truman