Mitragynine

How Enhanced Kratom is Different from Super and Premium Kratom? Kratom, whose scientific name is Mitragyna speciosa, is a medicinal plant that has been used for thousands of years in Southeast Asia. The plant only gained prominence in the Western world in the last few decades. According to an excerpt on Kratomlegend, a leaf of this plant can contain up to 40 naturally occurring alkaloids, the potent ingredient that interacts with the nervous system of the human body to produce wide ranging health

activity are mitragynine and 7-hydroxymitragynine since they bind with the opioid receptors.. Mitragynine is the most abundant alkaloid in kratom. 7-hydroxymitragynine is a minor component that is more potent and can penetrate blood brain barrier more than mitragynine. It is believed that 7-hydroxymitragynine is 13-fold more potent than morphine. Mitragynine was first isolated 87 years ago and scientists are still not able to totally synthesize it in the laboratory. All the mitragynine used by

treatment. With the abundant alkaloid content of kratom, the most significant psychoactive ingredients are mitragynine and 7-hydroxymitragynine. The former being an opioid agonist acts similarly with true opiates like heroin among others. The difference between the mitragynine compound and opiates is that the latter is attracted more to the mu-opioid receptors in the brain, while mitragynine prefers the delta-opioid receptors. The ingredients that attach to each specific type of receptors present

It’s been used traditionally as both a medicine and a textile. It’s reportedly helpful for treating drug addiction, and its consumption has never resulted in a documented death from toxic overdose. But the Drug Enforcement Administration (DEA) considers it a dangerous drug with no medical value. Sound familiar? No, this isn’t about Cannabis. This is about the leaves of a native Southeast Asian tree commonly known as “Kratom.” Its official botanical name is Mitragyna speciosa, and it’s the only

stimulating effect, while in larger doses acts similar to an opioid-like effect. M. speciosa is made up of more than 25 alkaloids that vary in specific composition depending on the plant’s geographical location. “ Structurally similar to yohimbe, mitragynine is the most abundant of these alkaloids and is thought to be primarily responsible for Kratom’s opioid-like effects” (Rosenbaum et al., 2012, p. 22). A cross-sectional survey of 136 Malaysian Kratom users is provided documenting that 88% of short-term