Neoplasm

Taking a shower, washing your car, living life, all require one common element, water. Roughly seventy percent of the surface of Earth is liquid, that’s a lot of H2O. With such an abundance of this natural resource why do so many not have access to a reliably clean source? Industrialization was the problem for the residents of Hinkley, California as portrayed by director Steven Soderbergh’s 2000 drama titled Erin Brockovich. A movie that made the public aware of a life threating substance found

There are three types of radiation that can bring about occupational exposure. Alpha radiation can be stopped by something as thin as a piece of paper or one’s hand (BBC, 2014). Those at risk for this exposure are those who install and maintain smoke detectors, which use Americium-241. In this mechanism, an electron current interrupts smoke particles, causing the alarm to trigger when it senses smoke (Bennett, 2017). Radium 226, which is an element that is injected into tumors to battle cancer

Discuss the workup of cervical lymphadenopathy. How would your recommendations differ for adult, pediatric, and geriatric patients? Cervical lymphadenopathy is the enlargement or swelling of the cervical lymph nodes. Cervical lymph nodes are the lymph nodes located at the anterior and posterior aspect of the neck and under the jaw. A thorough knowledge of the anatomy of the neck is essential to formulate a differential diagnosis. Cervical lymphadenopathy is not uncommon, especially in children and

13It is well documented that many types of tumours contain cancer cells with heterogeneous phenotypes reflecting aspects of the differentiation that normally occurs in the tissues from which the tumours arise. The variable expression of normal differentiation markers by cancer cells in a tumour suggests that some of the heterogeneity in tumours arises as a result of the anomalous differentiation of tumour cells. Examples of this include the variable expression of myeloid markers in chronic myeloid

Introduction The property of a cell to phagocytise or engulf another cell similar to its own or any other is termed as cellular cannibalism. It was first described by Leyden in 1904 and were referred as “bird – eye cells”. They are also known as “signet-ring cells”, due to their appearance. [1] [2] Cannibalistic cells were initially noticed in cytological smears where the cell had ingested another cell. These cells consisted of a vacuole with the ingested cell and this vacuole pushed the nucleus

Recent studies including a genome-wide study of certain cancers have come to demonstrate that the most common and most aggressive type of brain malignancy, or glioblastoma (GBM) comprises a shared link: alterations in the catalytic protein, isocitrate dehydrogenase (IDH) (1). The focus of such research is the mutant forms of NADP-dependent homologous enzymes IDH1 and IDH2 (2) - localized predominantly in cytosolic and mitochondrial regions, respectively. Both of these heterozygous point mutations

deaths per 100,000 U.S. of male population and 643.4 deaths per 100,000 of female population; the infant mortality rate was 6.75 deaths per 1000 live births (HHS, 2011). The leading causes of death in the U.S. are cardiovascular diseases, malignant neoplasms, chronic respiratory diseases and unintentional injuries (HHS,

Evaluating a Systematic Review or Meta-Analysis Overall Relevance: 1. Is the article proposing to answer a specific clinical question or questions? What are the questions? This article is looking to determine if it is effective practice for primary care providers to perform routine screening for skin cancer in their patients. Effectiveness of screening is described as early detection of melanoma and nonmelanoma skin cancer in order to reduce mortality and morbidity rates. 2. Is

1.Title: Prognostic impact of MYC rearrangement in progression of plasma cell myeloma Introduction Acquired chromosomal abnormalities are considered as an important prognostic marker in several hematologic malignancies. Cytogenetic aberrations play an important role in pathogenesis of disease and survival outcome. Here, our goal is to study the prognostic impact of Myc abnormalities and their role in progression of multiple myeloma. The study will also include cyclinD1 gene rearrangement; the most

Carcinoid Lung Tumors: Identification and Treatment Options Introduction Cancer is described in the Merrium-Webster dictionary as: a serious disease caused by cells that are not normal and that can spread to one or many parts of the body. That does not begin to describe the changes in the histology of the cell or to the body’s systems that cancer causes. Cancer is a small word that describes an all encompassing and ever changing disease. Neuroendocrine cancers are rare, so rare that there are