Neurogenesis

Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside within distinct regions of the adult brain. This phenomenon was first described over 50 years ago and it is now firmly established that new neurons are continually generated in distinct regions of the adult brain. The potential of the neurogenesis process lies in improved brain cognition and neuronal plasticity particularly in the context of neuronal injury, neurodegenerative disorders. In addition, adult

1. The original researchers were trying to investigate the effects of Adult Hippocampal Neurogenesis (AHN) on exercising. Hippocampus is a key area of the brain for learning and memory. 2. An experimental study was conducted. 3. The sample was composed of rats. Independent Variable- The three different workout groups the rats were placed in. The rats were divided into running, weight training and high-intensity interval training. Dependent Variables- The increase of brain volume neurons.

Could inducing neurogenesis be a future treatment for autism, psychopathy and other disorders linked to functional deficiencies of the amygdala? It has been demonstrated by research that some neurogenesis occurs in the hippocampus and amygdala, which work together to impact memories, emotions and learning, and they are considered responsible for social intelligence. Clinical psychopaths have been shown to have reduced activity in the amygdala when given certain stimuli. Some research suggests

modulation of learning and memory- A role for hippocampal neurogenesis? Hippocampal neurogenesis Neurogenesis is the birth of new neurons. It is a multistep process which consists of asymmetric division of neural stems ultimately leading to the generation of new neurons. In the hippocampus, neurogenesis occurs predominantly during embryonic development and also during adulthood (Altman and Das, 1965). In the human brain, adult neurogenesis occurs in the subgranular zone of the dentate gyrus throughout

regions in the adult brain are the subgranular zone (SGZ) of the dentate gyrus (fig1e) of the hippocampus and the subventricular zone (SVZ) of the lining of the lateral ventricles (fig1d). Comparison of adult hippocampal neurogenesis versus SVZ-OB neurogenesis: Neurogenesis is a highly regulated multi-stage process that consists of three phases: (1) the proliferation of neural stem cells and the subsequent expansion of intermediate progenitor cells, (2) the migration of newborn neuroblasts to

or alternatively enhancing neurogenesis. This limbic structure is readily influenced by the stress response, namely the hypothalamic pituitary adrenal (HPA) axis (Kolb and Whishaw, 2013). Aged individuals tend to exhibit elevated levels of corticosteroids, which promote hippocampal deterioration (Cameron and McKay, 1999). A specific region within the hippocampus, the dentate gyrus, is unique in that it not only succumbs to such effects but continues to undergo neurogenesis (Cameron and McKay, 1999)

The Effect of Aging on Neural Cells Introduction: Neurogenesis is defined as the creation of new brain cells. Before studies proved that neural cells do have the capacity to proliferate and repair themselves, it was often believed that species are born with a distinct amount of neural cells and as time passes, these cells would die without the ability to be healed or replaced. It was thought that the cells were mainly formed during the embryonic and perinatal stages in the mammals (Ming and Song

of this disorder as well as highlight flaws in the original theory. Among these is the neurogenesis theory of depression. This theory was established by BL Jacobs, H van Praag, and FH Gage (2000) through a review of work that had been performed in the 1990s. Upon evaluation of the previous literature, they found that drugs that increase serotonin such as d,l-fenfluramine also stimulate hippocampal neurogenesis. Due to this, they theorized that the birth of new neurons in the hippocampus was an important

(BDNF) expression and neuroplasticity (Yau, Gil-Mohapel, Christie, & So, 2014). This paper will explore the negative impacts that chronic stress and aging have on our brains’ plasticity and how we can reverse this through regular physical activity. Neurogenesis is defined as the birth of new neurons that can occur into and throughout adulthood (Yau, S., Gil-Mohapel, J., Christie, B. R., & So, K. (2014) . This process plays a fundamental role in neuroplasticity. Neuroplasticity is the brain’s ability to

accentuates the relationship between the hippocampus and MDD being mediated through stress. There are various hypotheses regarding what may cause hippocampal volume diminution as a consequence of stress. Major propositions involve hippocampal neurogenesis in the dentate gyrus (Becker and Wojtowicz, 2007), glial numbers, apoptosis (Czeh and Lucassen, 2007) and granule neuron numbers (Boldrini et al., 2013). Other mechanisms that may affect hippocampal volume like neuropil reduction, shifts in fluid