Neuromuscular disease

The peak of the CAP changes with different strength stimulus because the sizes and thresholds of the nerve fibres within the nerve is different. Larger nerve fibres have lower threshold stimuli than smaller ones, hence larger fibres were activated first, followed by smaller ones. As stimulus strength increased, the larger nerve fibres began firing followed by the activation of the smaller ones (refer to Figure 2). At the maximal stimulus a constant pattern was formed. This was because all the nerve

This activity is the critical driving force of muscle contraction. The stream of action potentials along the muscle fiber surface is terminated as Acetylcholine at the neuromuscular junction is broken down by acetyl cholinesterase. The release of Calcium ions is ceased. The action of the myosin molecule heads is obstructed because of the change in the configuration of troponin and tropomyosin due to the absence of calcium

Experiment 2: Skeletal Muscle ABSTRACT Frog skeletal muscle is used as an animal model to study muscle contraction. The objectives of this experiment is to demonstrate the physiological responses of skeletal muscle to electrical stimuli using frog gastrocnemius, to understand twitch, summation, tetanus and fatigue, to investigate the relationship between initial tension and force of contraction, to explore the differences between human and frog skeletal muscle. The threshold voltage is 0.4V. The

electrical stimulation to move and the person feels weak. As the disease progresses, all the motor neurons die and are not regenerated so, the patient is left paralyzed, losing the ability to speak, swallow and breathe (Ignatavicius & Workman, 2010). A distinctive characteristic of ALS is that although the motor neurons die, the brain, cognitive functions and sensory neurons stay intact (Porth & Matfin, 2009). This makes the disease especially devastating because patients become trapped inside their

LABORATORY REPORT Activity 2: Twitch Contractions and Summation PREDICTIONS Effect of Muscle Fiber Length on Contraction 1. As muscle fiber length increases: contraction force increases, becoming maximum at an optimal length, then decreasing at longer lengths. Effect of Stimulation Frequency on Contraction 2. As the frequency of stimulation increases, the force of contraction: increases. MATERIALS AND METHODS Measurement of Threshold Stimulus 1. Dependent Variable: contraction force

An integration center in the reflex arc is a neuropathway that creates a reflex action to activating neurons to skip the spinal cord and protect your brain. The nerve cells can be categorized by their connections, structure, and neurotransmitters. The structural classification is depending on shape and size of the cell body, its dendritic tree, axon length, and the nature of the connections it makes. The neurons with one, two, or more than two neurites, are unipolar, bipolar, and multipolar respectively

The purpose of the study is to establish the relationship between cognitive disability and mechanics of timed up and go(TUG) in the individuals with multiple sclerosis (MS). Cognitive abilities directly influence the performance of functional abilities; independence and social life of the individuals with MS.1 TUG is an important measure of functional measure in healthy and diseased population.6 Cognitive disability such as memory attention, execution of task, fluency and information processing speeds

Norah Carr Co-ordination and movement Lo3. March 2012. 3:1 eplain the sliding filament theory of muscle contraction with reference to the antagonistic muscles of the upper arm. 3:2. Draw and label a diagram of a synovial joint, explaining the functions of each structure. 3:3. Distinguish between a hinge, pivot and a ball and socket joint with reference to named examples, shapes of bones and the ranges of movement possible. To understand the sliding filament theory, one should first

INTRODUCTION Although passage of a tracheal tube over a fiberoptic bronchoscope has improved the ability to manage a difficult airway, however, this technique doesn’t ensure successful intubation,[1,2] especially after topical anesthesia of the tongue and pharynx with lidocaine spray, patients cannot tolerate fiberoptic bronchoscopy with discomfort.[3] The various audits of bronchoscopic practice have reported mortality rates of 0.01-0.5% and major complication rates of 0.08-5%, respectively.[4]

The Causative Agents, Treatment, and Symptoms of Clostridium Botulinum Lisa Xiong Microbiology 31 April 6, 2015 Many countries use the fermentation method in order to preserve or enhance the flavors of foods. However, the result of fermentation can also lead to drastic symptoms. For instance, the article “Food-Borne Paralysis from Eating Home-Pickled Eggs” from an Outbreak 37 article is about a 68-year-old man having symptoms involving paralysis and muscle weakness after eating the home-pickled