have seen patients with many conditions but patients with autoimmune neuromuscular disorders stood out the most because the patients had to be monitored frequently. Some examples of autoimmune neuromuscular disorders are myasthenia gravis (MG), Lambert-Eaton myasthenic syndrome (LEMS), Neuromyotonia, and Guillain–Barré syndrome (GBS) and autoimmune neuromuscular disorders are conditions that affect peripheral nerves, neuromuscular junctions or muscles. In fact, in the neuroscience field there is plethora
Kennedy’s Disease is an Incurable Neuromuscular Disorder. What is Kennedy’s Disease? Kennedy’s disease is an inherited neurodegenerative disorder that affects both the spinal and bulbar neurons. KD is a lower motor neuron disorder because it interrupts the transmission of nerve cell signals in the brain and spinal cord. This interruption affects the spinal and bulbar neurons causing the major symptoms muscle atrophy, weakness, contraction fasciulations, and bulbar weakness. KD is the first of the
classified as a chronic neurologic disease of the neuromuscular transmission and characterized by presentation of fatigable muscle weakness to the external ocular, cranial, respiratory and limb muscles (Smith, C., P.A.-C., & Stickler, D., M.D. 2012). The incidence of this disease is about 20 per 100,000 people in various populations, affecting mostly women in their 20’s to 30’s and men over the age of 60 (Postevka 2013). Myasthenia gravis is an autoimmune neuromuscular disorder that annihilation the
Myasthenia Gravis is a weakness and rapid fatigue of muscles under voluntary control. This disease is caused by an interruption in communication between nerves and muscles at the neuromuscular junction; this is the place where nerve cells connect with the muscles they control. The muscle weakness increases through periods of activity and then improves during rest. For example, muscles that control eye and eyelid movement, facial expression, chewing, talking, and swallowing, these are the most often
kinematics of hip and pelvis joints. The ADIM, a neuromuscular control exercise, increases function of the TrA and internal oblique (IO) to create improved trunk stability. The objective “was to examine the influence of the ADIM on forward steps as a gait exercise.” A convenience sample of 20 healthy male volunteers from a university was obtained. At the time of testing, these participants did not have any known lower back pain or neuromuscular disease.
The ability to walk is something that our society seems to take for granted. A neuromuscular disease can take that ability away instantly. As with any neuromuscular disease, the body’s muscles are specifically attacked. Normally that attack is caused by a lack or mutation of a specific gene. Duchenne Muscular Dystrophy (DMD) has a direct relationship with a lack of dystrophin synthesis. It is possible that the dystrophin synthesis can be increased by manipulation of microRNA-31. When looking at
Local Disease - Myasthenia Gravis Introduction Myasthenia Gravis is an autoimmune disorder in which antibodies destroy neuromuscular connections which leads to problems with the nerves that control muscles. The disease is characterized by weakness and fatigability of skeletal muscles. The muscles mainly affected are that of the eye, mouth, throat and limbs. The key concept underlying the disease is the decrease in the number of available acetylcholine receptors at neuromuscular junctions due
network with the Muscular Dystrophy Association (MDA). While learning about the work the association does, I realized that I want to do similar work. In my effort, I worked on a promotional campaign for the Muscular Dystrophy Association. Neuromuscular diseases, like Muscular Dystrophy, take away physical strength and eventually life. The Muscular Dystrophy Association (MDA) fights to find a way to give back strength, independence, and life. The work they do truly changes lives; however, they need
information………………………………………………………………2 • The normal functioning of an organ and Pathogenesis of the disease……………………………………………………………..2 • Symptoms………………………………………………………………………………….2 • Diagnosis…………………………………………………………………………………..3 • Treatment………………………………………………………………………………….3 • Conclusion………………………………………………………………………………...4 • References………………………………………………………………………………..4 Introduction Myasthenia gravis is a disease that affects voluntary muscles of the body; it causes the weakening of the muscles. In this
What do you think of when you hear the word muscular dystrophy? Some people may have no idea as others may have firsthand experience dealing with this disease or having extensive knowledge on the subject. The purpose of this paper is to inform any healthcare professional, anyone taking care of someone with muscular dystrophy, or anyone interesting on being informed about Muscular dystrophy. This paper will provide an overview of muscular dystrophy as well as the different types and the problems