Neuromuscular junction

NAME Rachel Brockhuis LAB TIME/DATE _______________________ Exercise 2 Skeletal Muscle Physiology The Muscle Twitch and the Latent Period 1. Define the terms skeletal muscle fiber, motor unit, skeletal muscle twitch, electrical stimulus, and latent period. Motor unit- single α-motor neuron and all of the corresponding muscle fibers it innervates; all of these fibers will be of the same type Skeletal muscle fiber- long and narrow cells that often span the entire length of a muscle Skeletal muscle

The peak of the CAP changes with different strength stimulus because the sizes and thresholds of the nerve fibres within the nerve is different. Larger nerve fibres have lower threshold stimuli than smaller ones, hence larger fibres were activated first, followed by smaller ones. As stimulus strength increased, the larger nerve fibres began firing followed by the activation of the smaller ones (refer to Figure 2). At the maximal stimulus a constant pattern was formed. This was because all the nerve

Normal Anatomy and Physiology of Motor Function The two components of the central nervous system (CNS) are the brain and the spinal cord. Communication between the brain and the spinal cord happens through motor neurons, which are nerve cells that enable motor movement. Each motor neuron is made up of a cell body, which holds all the cell components, dendrites which send information it receives to the cell body, and an axon which sends nerve impulses to the muscle (Porth & Matfin, 2009). As electrical

Norah Carr Co-ordination and movement Lo3. March 2012. 3:1 eplain the sliding filament theory of muscle contraction with reference to the antagonistic muscles of the upper arm. 3:2. Draw and label a diagram of a synovial joint, explaining the functions of each structure. 3:3. Distinguish between a hinge, pivot and a ball and socket joint with reference to named examples, shapes of bones and the ranges of movement possible. To understand the sliding filament theory, one should first

INTRODUCTION Although passage of a tracheal tube over a fiberoptic bronchoscope has improved the ability to manage a difficult airway, however, this technique doesn’t ensure successful intubation,[1,2] especially after topical anesthesia of the tongue and pharynx with lidocaine spray, patients cannot tolerate fiberoptic bronchoscopy with discomfort.[3] The various audits of bronchoscopic practice have reported mortality rates of 0.01-0.5% and major complication rates of 0.08-5%, respectively.[4]

as a chronic neurologic disease of the neuromuscular transmission and characterized by presentation of fatigable muscle weakness to the external ocular, cranial, respiratory and limb muscles (Smith, C., P.A.-C., & Stickler, D., M.D. 2012). The incidence of this disease is about 20 per 100,000 people in various populations, affecting mostly women in their 20’s to 30’s and men over the age of 60 (Postevka 2013). Myasthenia gravis is an autoimmune neuromuscular disorder that annihilation the functional

Being at a railway junction (a parallel to the junction in their lives) they are in veritably the "middle of nowhere" in northeastern Spain. This physical isolation The time constraints imposed by their mode of travel only magnifies the exigency of their decision. They are only at this junction for forty minutes, and once the train arrives they have only two minutes to board. The detail that it is the "express

the muscles it has to pass the space between the end of the nerve and the muscle, and that space is called neuromuscular junction. The message is transmitted from the brain to the end of the nerve and from the nerve to the neuromuscular junction, and when the message arrives the chemical called neurotransmitters are released. When acetylcholine reaches the muscles side of neuromuscular junction, it attaches and locks into receptors. If anything interferes with these steps, the nerve will not be able

Myasthenia Gravis is a weakness and rapid fatigue of muscles under voluntary control. This disease is caused by an interruption in communication between nerves and muscles at the neuromuscular junction; this is the place where nerve cells connect with the muscles they control. The muscle weakness increases through periods of activity and then improves during rest. For example, muscles that control eye and eyelid movement, facial expression, chewing, talking, and swallowing, these are the most often

Myasthenia Gravis is an autoimmune disorder in which antibodies destroy neuromuscular connections which leads to problems with the nerves that control muscles. The disease is characterized by weakness and fatigability of skeletal muscles. The muscles mainly affected are that of the eye, mouth, throat and limbs. The key concept underlying the disease is the decrease in the number of available acetylcholine receptors at neuromuscular junctions due to an antibody mediated auto-immune attack. The disease was