Ophthalmic drug delivery is the most complicated drug delivery due to its unique anatomical and physiological barriers. Viruses, bacteria and fungi are the three most common pathogens causing various ocular disorders. The infections can be either local, where only the ocular tissues are infected or systemic where the infection spreads to various other organs. Immunocompromised patients are more prone to these infections. While some infections are self-limiting and benign, others are associated with
stability, sensitivity and adaptability of the drug excipients to self-emulsified form. In olden days, SEDDS are prepared in the form of liquid state where it will be enclosed by hard or soft gelatin capsules. By this, it helps to enhance oral administration and later on it is known to burden in the formulation. Main disadvantages are low drug incompatibility and stability, drugs leakage and precipitation, capsule ageing and it is very costly. Besides, addition of large quantity of surfactants in
One formulation approach that could be used in order to develop a one-month sustained release formulation of compound 5 as a microbicide would be using intravaginal rings. Intravaginal rings are flexible and torus shaped devices that are placed in the vagina (adjacent to the cervix). A concentration gradient is formed when the device comes into contact with the vaginal lumen and hence the drug is released. The rings are usually made up of silicone or ethylene vinyl acetate. The efficacy is maximized
Bright House Networks. She has over 15 years of experience managing, public relations, and sales channels. She has crisis-management skills and media relations. She has a history working with ABC, CBS, NBC, and FOX news. Dillaway showed the class commercials for Bright House and explained the approaches that were taken to reach different customers. I will apply the concepts Dillaway used and apply them to our textbook. In chapter 13 Public Relations and Marketing is the main focus. Marketing is the process
A Life of a System Administrator The typical life, what a person goes through as a system administrator in the field. There are many situations of a system administrator that’s negative or positive for them. System administrator’s deals with many situations that their clients are either complaining or satisfied with the work they do. The teams of system administrators deal with all types of problems in their field. System administrators are problem solvers as well as technical problem solvers in
Our company name: Virtual Pharmaceutical Drug name: VPL874C (Market name = Betatrix) Possible indications = migraine prophylaxis, hypertension, coronary heart disease Problem – want oral dosage form. - but has short half life (3-4hr) Solution – oral dosage form with extended release which releases drug slowly so that the plasma concentrations are maintained at a therapeutic level for a prolonged period of time (usually between 8 and 12 hours). Recent extended release formulations
Debbie’s Dilemma By: Alisha Wallace 02/17/2014 HCA340: Managing in Health & Human Services (BTE1404B) Instructor: Lilia Chavarria Debbie chose to return to school with the hopes of a pay raise which is her motivation. According to Herzberg’s two factor theory there may have been have of been many reasons for Debbie’s motivation. “Wages, Hours, Working conditions, Relationships with supervisors, Relationships with peers” Baack, D. E. & Fischer, A. (2013) can
Based on United State Pharmacopeia, pastes are defined as semisolid dosage forms that contain one or more drug substances intended for topical application. (Pharmaceutical Dosage Form, 2009) Pastes are intended for application to the skin, oral cavity, or mucous membranes. Pastes are usually prepared from fats, fatty oils, petrolatum, paraffin, waxes, glycerin or water by mixing homogeneously powdered drug with the foregoing materials as bases. (General Requirements for Pharmaceutical Preparation)
When reviewing Rasmussen’s policies of academic integrity, the first very important step is to ensure that each student is informed as well as equipped to take on the assignments that are asked of them. As the instructor, it is important to continually make sure expectations are placed before the students in a clear, understandable, and attainable manner. Additionally, that resources are made available to help them meet these expectations. The initial gut reaction to the quality of Bridget’s assignments
through the middle and inferior rectal veins into systemic circulation by passing the hepatic first pass metabolism, which gives the rectal route of administration an extra advantage. Paracetamol is a well-known drug for its analgesic and antipyretic activity. It is available in oral, rectal and intravenous dosage form. The most common route of administration is the oral route as paracetamol is being absorbed well through this route with the bioavailability of 63-89%. [5] The absorption half-life through