Effects of Surfactants on Suppository Absorption Essay example

In an emergency situation, the drug would get into the patients’ blood stream faster, which would be advantageous to help the patient faster. Opposed to an oral route which would require the body to absorb the drug preceding going into the blood stream.

*Rectal administration – Medicines administered into the body by this route are absorbed very quickly. Suppositories are available for this route of administration and are inserted high into the rectum.

The objective of this extraction experiment was to achieve a comprehensive understanding, as well as master the practice, of the technique of separating various individual components of a compound.

The aspirin starts begins to dissolve by the enzymes and are soaked in while traveling down to the stomach. They then are distributed to the areas that need the pain relief.

Rectal-Administering drugs into the rectum are then become absorbed into the blood vessels and taken into the body.

The National Prescribing Centre recognize some fundamental differences in the absorption, distribution and excretion of medicines between adults and children. The differences are published in the National Prescribing Centre’s bulletin, produced by

Some medications can be inserted into the anus (rectally) as a suppository. They may contain active ingredients that are meant to have a local effect.

Absorption – “How the drugs enter the circulation process through the body, and how they resist general breakdown by the stomach, liver, and the intestines”. Some of the factors that affect the absorption of drugs in the body is as follows, “acidity of the stomach, Physiochemical properties, Presence of food in the stomach or intestine, and Routes of administration”,

enters the blood stream in just a matter of seconds of using this drug. When eating or drinking

A. Absorption-"refers to the movement of the drug from site of administration into the blood stream.

Topical drugs such as patches, ointment, and cream are applied directly on the skin and can be absorbed fast or with a delayed action. The term pharmacokinetics is the study of the movement of the drug in the human’s body. This includes the site of absorption (movement of drug from entry to tissue), how it is distributed (movement in the circulatory system to intended destination), how it is metabolized (break down in the liver), and excretion (elimination from the body). This unit also described the term half-life, which is how long the human body takes to break down a drug, absorb and excrete it and short half-life, which are medications excreted by the body quicker than long half-life drugs. The term pharmacodynamics is any of the changes in the patient’s body resulting from the medicine taken. It is highly important for the patient to know of the used drug’s side effects (unintended effects), adverse effects (unintended effects that can be harmful), and any possibilities of allergic reactions (most severe adverse response of a

Acetaminophen was added to the British Pharmacopoeia in 1963. It became very popular once it was released. The reason why it became very popular was because it had very few side effects, unlike aspirin which irritated the stomach. The United States use generic versions of the drug. The drug acetaminophen is called paracetamol in countries located outside of the United

Pharmacokinetics consists of three components, absorption, distribution, and clearance. Absorption, especially from the oral route is the least influenced by the aging process and slows down, but remains complete (Adams et al., 2011). As the number of drugs ingested increases, the risk that absorption is interrupted increases (Adams et al., 2011). Distribution is significantly impacted with age. Older people have more body fat and less water than younger people. As a result, a drug that is fat soluble will remain in older bodies

3Transdermal delivery of fentanyl has a variety of advantages compared to other delivery systems. Unlike oral administration, transdermal fentanyl avoids first–pass hepatic effect of the liver, which can prematurely metabolize drugs. In comparison with oral opioids, transdermal fentanyl has a lower incidence and impact of adverse effects such as constipation and vomiting, it also enhances patience compliance (as administration is every 72 hours). Transdermal delivery of fentanyl is also more convenient in comparison to hypodermic injection which can be very painful but also exert dangerous medical waste and increase disease transmission with the re use of needles (which is very common in developing countries).

Applications outside the intestine are called parenteral. One form is an injection, which can be subcutaneous (under the skin), intramuscular (into a muscle), or intravenous (into a vein). Parenteral administration of an antibiotic is used when a physician requires a strong, quick concentration of the antibiotic in the bloodstream. Manufacture.