Rhesus Macaque

Animal testing is a process of using animals in conducting scientific experiments (Christopher 14). The practice is also widely referred to as animal research or animal experimentation. In efforts to understand how the human body reacts and behaves in different conditions, animals are used as an experimental substitute in finding or establishing relevant solutions related to items or substances that humans use on a day to day basis such as cosmetics, household merchandise, food preservatives, industrial

entry of the studied enzyme was found: P29466. From this accession code, a homologous protein with 48.6% similarities was found. This homologous protein was called Caspase-4 isoform alpha (Uniprot accession number: H9Z2M5) found in Macaca mulatta (Rhesus macaque). Using the BLAST results, an alignment (Figure 1) between chosen sequences were analyzed. The active site function was the same for both. Based on Fig. 1, the active site for Caspase-1 is His237 and Cys285 and for Caspase-4 isoform alpha the

Tracking the History of the Elusive HIV Vaccine I. Introduction Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is a global epidemic: 25 million people have died from it and 35 million people are currently infected1. While anti-retroviral therapies are available that control viral replication, those treatments are unable to purge the latent reservoir of virus resident in resting CD4+ memory T cells. Additionally, these treatments are extremely expensive and largely unavailable

hybridization revealed that a large pool of virus is established on FDCs very soon after infection (Schacker et al., 2000) and that lentiviral deposition and productive infection in the follicle is much higher in pathogenic hosts such as humans and Rhesus macaques compared to non-pathogenic hosts such as sooty mangabeys (Brenchley et al., 2012). Finally, in-situ techniques are key to demonstrate the failure of HIV-1 specific CD8 cytotoxic T lymphocytes in B cell follicles, thus

The Zika virus originates from the Zika forest of Uganda. During a study on yellow fever in 1947, the virus first revealed itself through the blood of a rhesus macaque located inside of the Zika forest. After its discovery, no evidence suggested that the virus could cause human diseases. Nevertheless, serosurveys were conducted in various regions of Uganda. Through these surveys, a 6.1% seroprevalence of antibodies against Zika virus was discovered. This added insight on to the frequency of human

Children who are abused or neglected are more likely to commit delinquent acts and develop personality disorders such as antisocial personality disorder. Child abuse includes sexual, physical, psychological or neglect. Sexual abuse is rape, intercourse, rape, fondling or sodomy. Physical abuse is harming or inflicting damage by punching, kicking, hitting, slapping, burning or beating. Psychological abuse includes mental, verbal and emotional abuse which is berating words, derogating remarks, lack

Many students know mitochondria as “the powerhouse of the cell” whose main role is to make energy for the cell. Mitochondria produce the majority of the body’s energy. While energy synthesis is a very important role, it is not the only role that mitochondria play. Production of a mitochondrion requires 3000 genes; the mitochondrion itself codes 37 genes, called mitochondrial DNA (mtDNA). The nucleus houses the rest of the genes. For ATP synthesis, mitochondria use about 3% of its three thousand genes

Large animal models for neurodegenerative diseases Numerous human genetic disorders, such as neurodegenerative diseases, occur because of genetic mutations in human cells. New genome editing tools – as of 2014 - such as transcription activator-like endonucleases (TALENs) or CRISPR/Cas9 further ease the precise generation of non-human primates (NHP) models for human diseases. Several of these NHP models displayed clinical manifestations like those of human disorders, in comparison with rodent models

For this paper I am going to focus on B. F. Skinner’s Behavioral Approach on analyzing myself. Behaviorism emerged in the early years of the twentieth century as a counterbalance to the psychoanalytic approaches of therapy and psychology. Skinner was born in 1904, just nine years after Freud published Studies on Hysteria. Both of these opposing theories, psychoanalysis and behaviorism, have greatly influenced the way we think of the human mind. I lean more towards the behaviorists approach because

Behaviorism and Attachment For this paper I am going to focus on B. F. Skinner’s Behavioral Approach on analyzing myself. Behaviorism emerged in the early years of the twentieth century as a counterbalance to the psychoanalytic approaches of therapy and psychology. Skinner was born in 1904, just nine years after Freud published Studies on Hysteria. Both of these opposing theories, psychoanalysis and behaviorism, have greatly influenced the way we think of the human mind. I lean more towards the behaviorists