Simplex virus

from the Latin herpes which, in turn, comes from the Greek word herein which means to creep. This reflects the creeping or spreading nature of the skin lesions caused by many herpes virus types. There are at least 25 viruses in the family Herpes viridae (currently divided into three sub-families). Eight or more herpes virus types are known to infect man frequently. Once a patient has become

course of infection. The virus can cause diseases or be silent for a long time only to be reactivated when the host’s immune system has fallen. Among the twenty-five strains that exist, only eight are known to be infective to human, mostly individuals over the age of 40. They are classified as Herpes Simplex Virus (HSV-1) oral herpes, Herpes Simplex Virus (HSV-2) genital herpes, Epstein-Barr Virus (EBV), Cytomegalovirus (CMV), Varicella Zoster Virus (chicken pox), Human Herpes Virus 6, HHV 7 (lymphotropic

structure. They all have icosahedron envelope, the matrix and the capsid. The virus seems to replicate the immune defense of its host to insure successful replication. All the herpes viruses share common features like replication strategies. Each herpes viruses is different but we will focus on the herpes simplex virus type 1. Source: http://myscoopy.com/car/hsv-1 HSV-1 is a double stranded DNA virus. It being a herpes virus it is a member of the alpha-herpesvirus group, meaning its primary agent

Encephalitis typically appear two days to two weeks after exposure to the virus or bacteria. In many minor cases, symptoms convey to that of flu-like signs. In severe cases symptoms can be comprised of: headaches, vomiting, sensitivity to light, personality changes, loss of consciousness, and partial paralysis. Patients who display any symptoms should seek medical attention immediately. Encephalitis symptoms seen in infants with herpes virus Encephalitis may develop lesions in the mouth, in the eye, or on

Oncolytic virotherapy Introduction An oncolytic virus (OV) is a virus that preferentially infects and kills cancer cells. OVs posses the ability to selectively infect and replicate in cancer and associated endothelial cells and kill these cells in cancerous tissues while leaving normal tissues unharmed [1]. As the infected cancer cells are destroyed by lysis, they release new infectious virus particles to help destroy other cancer cells or the remaining tumor. The viruses achieve this by a number

Communicable Disease: Genital Herpes Virus (HSV-2) Introduction Genital herpes is reported as a "common and highly contagious infection usually spread through sex." (WebMD, 2012) Herpes is an infection resulting from the herpes simplex virus-2 (HSV-2) which is similar to herpes simplex virus-1 (HSV-1) which is the virus that causes cold sores. Individuals infected with the herpes virus have recurrent outbreaks in fact 90% of individuals infected with the herpes virus report repeated outbreaks with

Viruses are tiny organisms that contain nucleic acid encased by a protein coat. Some are enclosed by an envelope of fat and protein molecules. This organisms cannot grow, reproduce or carry out their functions without a host cell. A virus invades living cells and uses their chemical properties in order to keep itself alive and reproduce. As they don’t have ribosomes they are not able to synthesise proteins and they are also unable to generate or store energy in the form of ATP. Therefore, they use

This virus brings about a lost lasting infection that affects the general nervous system of various individuals after they have acquired the infection for the first time. It is normally latent in nature, but various nonspecific or unexpected inflammations cause some reactivation for example herpes labialis (Mawanda & Wallace, 2013 pp.161). Some scientific studies have shown that HSV-1 can easily enter or penetrate human body by the help of various routes and can consequently repeatedly occur in absence

assembled into trimers, with six fold symmetry. The capsomers are assembled into arrays that have either p6 as in Paramecium bursaria Chlorella virus 1 or p3 symmetry as in Mimivirus (Xiao & Rossmann 2011). Mimivirus has a capsid (icosahedral) diameter of 400 nm with protein filaments of 100 nm from the surface of the capsid, comprising the total length of the virus up to 600 nm. While most of the other discovered large viruses size varies between 400 nm and 800 nm (Xiao et al., 2009). Mimivirus shares

encephalitis. Primary encephalitis is when the viruses attack the brain through the blood stream and into the nerve cells; it is then grouped together and multiplies. After multiplying, it is spread throughout the brain. Secondary encephalitis is when the virus infects a person by first infecting the other tissues in the body and then attacks the brain. “Viruses that are transmitted from other tissues usually cause focal infection, meaning they produce extensive damage in only a small area of the brain” (Simon