When reflecting on the history of the human species, it is said that the narrative of mankind and infectious diseases are intertwined. For centuries, humans have been exposed to a seemingly infinite amount of contagions. Many viruses, bacteria, and fungi have plagued human beings for ages and have eradicated populations thousands at a time. Through medical innovations and the advancement of scientific knowledge, humans have been able to combat disease and disease-carrying vectors. Through proper
Lymphatic filariasis related to Wuchereria bancrofti INTRODUCITON Seventeen distinct diseases run rampant through developing countries, known as the neglected tropical diseases. They infect an average of 2.7 billion people world wide, but mainly infect those living in poverty stricken countries. These diseases can lead to life-long disabilities, disfigurement, and promote poverty. Most of the infected countries live on an average of two U.S. dollars a day with no access to healthcare, making some
Organization eliminate Lymphatic Filariasis as a health problem. Wuchereria bancrofti worms are the parasites causing around 90% of the lymphatic filariasis cases. One abnormal condition resulting from the disease is a swollen scrotal sac due to fluid collection. A procedure called Immunochromato graphic card test or ICT is a simple test used to detect adult levels of transmission. This test uses ultrasonography to detect the adult Wuchereria bancrofti worms in the scrotal lymphatic vessels. Ultrasound exams
Lymphatic Filariasis Introduction Over 120 million people worldwide are affected by lymphatic filariasis. This disease is caused by nematode worms, most of the cases being from a species known as Wuchereria bancrofti, or just W. bancrofti. Those who experience the conditions of the disease the worst are older individuals whom have lived in an endemic area for an extended period of time. This is because of the long gestational period for the parasitic presence to become prevalent by repeated mosquito
Elephantiasis What is Elephantiasis? Elephantiasis, also known as lymphatic filariasis, is a parasitic infection that results in extreme swelling in the legs and arms. This condition is generally caused by the filarial worm that is transmitted from person to person through the female mosquito. At times an infected female mosquito bites a person; she might inject the worm larvae into their bloodstream. The worm larvae then replicate and extend throughout the bloodstream. Elephantiasis can put impact
inflammatory/immune mediators, molecules of parasite, Wolbachia and other factors contribute to pathogenesis and development of LF disease. The secondary bacterial infections further complicate the pathology. The adult and developing worm of Wuchereria bancrofti,
While this infection does cause harm to the lymphatic system, it still affects the integumentary system (skin). The skin and lymphatic system go hand in hand when this infection is present in the individual. This is seen when the skin reacts to the decreased function of the lymphatic system due to the parasitic worm. History of Lymphatic Filariasis It is unknown of how or where this infectious disease (lymphatic filariasis) arouse. The first documentation of lymphatic filariasis was not seen until
Lymphatic filarial disease is a disease that is caused by a parasitic infection of the lymphatic system. The parasites that cause this disease are found in the roundworm nematode family -- there are three types that cause it. The primary one is Wuchereria bancrofti; the other two are Brugia malayi, and Brougia timori (Centers for Disease Control and Prevention [CDC], 2013). The severity of infection ranges from asymptomatic, acute clinical, to chronic (World Health Organization [WHO], 2015). In all cases
a large cohort of type 2 diabetic patients. Being an active chitinase, the wild type and fully active human chitotriosidase enzyme is essential for the resistance against many chitin coated pathogens such as Plasmodium falciparum [22], Wuchereria bancrofti [23], Cryptococcus neoformans and Candida albicans [24]. This is evidenced by the almost complete absence of the 24-bp duplication mutation of CHIT1 gene in sub-Saharan Africa (0-2% of individuals) confirming the evolutionary advantage of the
Insects-the most diverse group of animals on Earth, are the major group from arthropods class. Insects could be found in almost everywhere, in any conditions, and environments, which why we would classify insects as the most successful, and diverse organisms to dominate the earth’s population. However, these magnificent, simple yet sophisticated organisms are capable to produce massive casualties. The manner of how these diseases are introduced to human through insects will further be discussed in