Autism Spectrum Disorder

In 1979 Thomas Bouchord conducted a study of 20 years on twins , it involved 81 pairs of identical twins and 37 pairs of fraternal twins. In one case pictures were taken of the

Monozygotic twins: Monozygotic twins are also known as identical twins. These twins start their life as one egg which is fertilized by one sperm and latter splits into two eggs much earlier in the gestational period. These are very rare and have no link to heredity. But studies reveal that only one of four conceptions of twins is identical. Therefore, it seems likely that any differences between twins will have to be caused by environment rather than by genetics.

Parallel to this, the focus on genetics is Particularly convicted in twin studies, which establish a comparison between monozygotic twins that are identical and dizygotic twins, which are opposingly non-identical. This distinction can be identified in Torgersens study, which compared MZ and same sex DZ twins where one proband had an anxiety disorder, and it was discovered that such disorders were 5x more frequent in MZ twin pairs, who mutually shared identical genetics.

As Joseph (2004) pointed out, however, this is not always the case. Monozygotic twins are more likely to be treated in a similar way, encounter more similar environments, and be to be thought of as ‘the twins’ rather than two separate individuals. This, in turn, can lead to ‘identity confusion’ and so potentially a higher concordance rate amongst monozygotic twins. Therefore Joseph argues that the greater concordance rate seen in monozygotic twins than in dizygotic twins is a result of the differing attitudes and environments experienced by the two types of twins.

Chapter 1 focuses on autism, Pervasive Developmental Disorders (PDDs) and other Autistic Spectrum Disorders (ASDs). Described in 1943 by Dr. Leo Kanner, autism (also known as autistic disorder, childhood autism, or infantile disorder) is one of the PDDs along with Rett's disorder, Childhood Disintegrative Disorder (CDD) referred to as Heller's syndrome, Asperger disorder, and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS). Rett's is a rare genetic abnormality affecting brain development in girls. There are treatments available, but there is no known cure. Asperger disorder affects an individual's ability to socialize and communicate effectively. Individuals with Asperger disorder may be socially awkward and have a compulsive

The study of twins relies on studying teens raised in the same family environments. Identical twins (Monozygotic) share all of their genes, while fraternal (dizygotic) only share 50% of their genes. Researchers use this method to estimate the heritability of traits.

The work of Liu, King, and Bearman (2011) report that autism ""¦is a developmental disorder characterized by impairments in social interaction and communication, often accompanied by stereotypical or repetitive behaviors." (p.1387) Reported as well is that substantial resources are spent providing treatment to children in families who have been diagnosed with autism and specifically stated is that the resources needed are "significantly more than for other children neuropsychiatric and developmental disorders." (Liu, King and Bearman, 2010, p. 1387)

Autism is described as a neurodevelopmental disorder that inhibits characteristics like impaired social interaction, difficulties in verbal and non-verbal communication, cognitive disorders and repetitive behavior.

Autism is the main form of autism spectrum disorders (ASD). Autism is a developmental disorder that is manifested in problems with communication, impairment of social functioning, and repetitive behaviours. According to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), ASD diagnoses must meet four different areas of criteria. There are three symptoms of "deficits in social communication and interaction across contexts," four symptoms of "restricted, repetitive patterns of behaviour, interests, or activities," "symptoms must be present in early childhood," and the symptoms must "together limit and impair everyday functioning" (Carpenter, 2013). There are many theoretical positions on the causes of autism spectrum disorders. Some of which have been discounted by empirical studies that have been researched and performed.

Many of us have heard about Autism, also knows as Autism Spectrum Disorder (ASD). Some have a family member, a friend, or know someone who has ASD. Increasingly it is becoming a more common disability. “Autism is one of the fastest-growing developmental disorders in the U.S” (Autism Speaks). Autism has no respect for gender, race, social class and or ethnicity. “Autism is a pervasive developmental disorder that involves abnormal development and function of the brain.” (Autism Center of Excellence) People who have autism have a lot of difficulties with social skills, communication and also will develop behavior issues. These behavior problems of an individual with autism can vary at times and can go from mild to severe. According to the Autism Science Foundation it says,” Many people with the Autism Spectrum Disorder (ASD) also have unusual ways of learning, paying attention, and reacting to different sensations. The thinking and learning abilities of people with ASD can vary—from gifted to severely challenged.” The causes and symptoms, as well as the diagnosis, and the treatments of autism vary.

In the United States, the Center for Disease Control and Prevention reports that between 1 in 80 and 1 in 240, for an average of 1 in 110 children have an autism spectrum disorder, “ASD” (Nirv, Shah 2011). According to the National Institute of Neurological Disorders and Stroke, up to six out of every 1,000 children may be diagnosed with some form of autism. In addition, boys are four times more likely than girls to have autism. This means that as many as 1.5 million Americans today are believed to have some form of autism. Unfortunately, the numbers appear to be increasing rapidly. Autism is a disability that frequently appears during the first three years of life. It is the result of a neurological disorder that affects the

Neurological disorders are complex in nature and often the least understood. Given the recent boom in imaging technology and other diagnostic methods, it is now possible to see more clearly into the scope of neurological development and accurately determine the etiology of these diseases. One of such disorders is Autism; a multifactorial condition impairing normal brain development. It affects many aspects of development, including social behavior, cognitive ability and communication skills1 and is commonly diagnosed in children before the age of three1. The symptoms of this condition can vary greatly between individuals; hence its classification as a spectrum disorder. Asperger syndrome, Rett syndrome and pervasive

With the rate of autism being diagnosed on the rise, the amount of research and interest in the disorder has risen as well. Some research suggests that over the past two decades the occurrence of autism has increased from approximately 2-5 per 10,000 births to about 1-5 per 1,000 births (Acosta & Pearl, 2004; Fatemi et al., 2012). Still others report that the occurrence is as high as 1 in 150 kids (Amaral, Schumann, & Nordhal, 2008). Even though the spectrum of autistic disorders has been studied since 1943, there have still not been any consistent nor persuasive causes or markers, either biological or clinical, identified with autism and its range of disorders (Santangelo & Tsatsanis, 2005). In fact, even with all of the advancements in genetic research technology and the increasing interest in autism, researchers can still only account for approximately 5-15% of autistic cases (Rogers et al., 2013).

A strength of twin studies is that they are an example of a natural-occurring variable: MZ twins share 100% of their genes, whereas DZ twins share about 50%. As the researcher doesn’t manipulate the variables themselves, the risk of researcher bias is

“Village idiot”, “court jester”, “witch”… could these be the original names for Autism Spectrum Disorder of recent history? It has been suggested that ASD stems from an aggregate effect of many damaged essential genes that "work" together during the early stages of development in the womb, as soon as eight weeks after conception.19 The prevailing theory for autism is that it is a polygenic or multi-factorial genetic disorder and presumes that there are multiple genes and multiple environmental forces that interact in some complex way to ultimately create the problem of autism.20 Research has shown that over the last decade that while diagnosis has increased over time, the actual percentage prevalence of autism has not risen.10