C-Diff Research Paper

700 Words3 Pages
Clostridium Difficile also known as C-Diff is a bacterial infection of the gastrointestinal tract of the human body. C-Diff is a gram positive bacillus, which is spore forming. C-Diff is one of the many superbug that health care workers and hospitals battle. There is a very large push by the Centers for Disease Control (CDC) to educate on hand hygiene and room decontamination for patients that have tested positive for C-Diff in a health care setting. This is because the spread of the disease is through the fecal-oral route, and with spores being able to live on contaminated surfaces for a long period of time.
C-Diff is an opportunistic infection, it will affect an individual whose flora in the intestines has been compromised by the treatment of antibiotics for a different infection like pneumonia, MRSA, etc... Antibiotics do not know what bacterial are good and what is bad. They kill all bacteria. This gives the C-Diff spores the opportunity to then take over the flora in the intestine that are being killed by the current regiment of antibiotics. C-Diff affects the flora of the large intestine
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Symptoms range from mild to severe infections. A patients will present with watery stools, dehydration, and mild to severe abdominal cramping, blood or pus in the stool, leukocytosis and even kidney failure. Detection of C-Diff is very easy for an experienced health care worker all you need is a good nose. C-Diff has a very familiar smell that one will remember. For laboratory testing, physicians will usually order a stool sample be taken. Stool can be tested for the presence of C-Diff toxins A and B. A microbiologist will run either an Enzyme Immunoassay (EIA), Polymerase Chain Reaction, or a Cell Cytotoxicity Assay. Each of these test look for C-Diff toxins in the human stool. Many hospitals will run the EIA and Cell Cytotoxicity Assay to collaborate positive
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