preview

Cell Membrane Permeability

Decent Essays

Only uncharged, small, polar molecules, (such as water) and hydrophobic molecules, (such as oxygen, carbon dioxide) and lipid-soluble molecules (such as hydrocarbons) can freely pass across the membrane. All ions and large polar molecules (such as glucose) are not permeable to the membrane.

Membrane structure

The plasma membrane maintains dynamic homeostasis by separating the internal metabolic events of the cell from its external environment and controlling the movement of materials into and out of the cell. The membrane is a double phospholipid membrane, also referred to as a phospholipid bilayer, and has polar hydrophilic ("water loving") phosphate heads around the outside and non polar hydrophobic ("water fearing") fatty acid tails on the inside of the membrane. Slight variations in these structure of the fatty acids in the membrane alter the fluidity of the membrane. Phospholipids with saturated fatty acid pack more tightly, because of the nature of their single carbon bonds. This leads to a more rigid membrane. Unsaturated fatty acids, which have double carbon bonds, limit packing and result in a more flexible membrane. Cholesterol molecules distributed throughout the phospholipid bilayer provide some stability to the plasma membranes of animal cells. At higher temperatures the cholesterol molecules allow the membrane to be firmer, at lower temperatures they allow for flexibility.
Fig. 1

Proteins

The mosaic nature of the proteins scattered within the phospholipid

Get Access