Cytokines And Antibodies-Protein Synthesis

Szuda, Stephanie “Health: Life with Lupus.” The Times. 11 Jan 2008. 19 Nov 2010. <Mywebtimes.com>

Lupus is an autoimmune disease that attacks women between the ages of 15 and 40. It occurs less often in men than in women. The people affected by lupus vary depending on the country or region. In the US alone, the prevalence rate is highest among Asians of Hawaii, blacks of Caribbean origin, and Native Americans of the Sioux, Arapahoe, and Crow tribes. Lupus is a disease that affects the immune system. We can think of the immune system as an army within the body with hundreds of defenders (known as antibodies). They defend the body from attack by germs and viruses. In lupus, however, the immune system becomes overactive and creates antibodies that attack healthy tissues in the body, such as: the skin, kidneys, lungs, heart and brain.

Some recent studies have reported that people diagnosed with Lupus have a significantly increased risk for Cancer, particularly leukemia and lymphoma. While this may make sense, at first glance, based upon the fact that Lupus is an autoimmune disease and, therefore, the immune system is compromised, there is still some question remaining as to whether higher incidents of leukemia and lymphoma occur in Lupus patients than within the general population. Exploring this topic would involve analyzing the incidence of comorbid Lupus & Cancer compared to Cancer in the absence of Lupus and Cancer in comorbidity with other autoimmune disorders.

Lupus is when your tissues and organs are attacked by your immune system without recognizing that they are doing it, and it will continuously do so.Lupus means wolf in latin and it was chosen to because of the red skin inflammation that affects you when you have this chronic disease. It was during the 19th century that this name was chosen. Lupus is a genetic disease, and people who have it genetically may get it activated by the environment. There is no clear cause, but there might be a few things that will give you Lupus symptoms. Being in sunlight may give you skin damage similar to the lupus ones. Sunlight can also give your body an internal response. Infections may start Lupus or bring it back to those who already have it. Anti-seizure medicines may also give you Lupus

Lupus is a chronic, autoimmune disease that can damage any part of the body like your skin, joints, and, or organs. When someone has lupus, something goes wrong with their immune system. Because it is an autoimmune disease, the immune system cannot tell the difference between the foreign invaders, like the flu, and the body’s healthy tissues. So it creates autoantibodies that attack and destroy the healthy tissue, which causes inflammation, pain and damage in various parts of the body. It is also a disease of flares meaning when the symptoms worsen, the person will feel sick, and remission, when the symptoms improve, the person will feel better. It is a disease that can range from mild to life threatening.

Systemic lupus erythematosus, or simply lupus is a chronic autoimmune disease or immune system malfunction. A person's immune system normally protects the person from viruses, bacteria and other foreign materials. When a person has an autoimmune diseases like lupus, the immune system turns against itself and attacks itself.

Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July

     Lupus is a potentially life threatening disease that effects about 1.5 million Americans. Lupus can effect many different parts of the body. Lupus is a type of autoimmune system disorder in which the body cannot distinguish the difference between foreign antibodies and its own organs. So basically what happens is that the body ends up attacking its own organs thinking they are foreign substances. (The Lupus Foundation of America)

Imagine you have a normal life, a simple nine to five job, relax afterwards by going out with some friends or staying in to do some tidying up. Everything is easy and nothing is holding you back. Now, imagine doing all those same things while being in pain or with a visible rash across your face. You call out more often, have a hard time focusing on simple tasks such as cleaning, and socialize less often. This has become your new normal. Unfortunately, this is the crushing reality for those who suffer from the chronic symptoms associated with lupus. In the information to follow, it will discuss what lupus is and what it’s symptoms are, how to diagnose and treat lupus, and what can be done to live as normal a life as possible.

Lupus is a chronic, autoimmune disease that can damage any part of the body. The skin, joints, or organs inside the body can be affected by this. Chronic means that the symptoms tend to last weeks and sometimes for many years. With lupus, the immune system makes autoantibodies instead of creating antibodies, which protect the body from bacteria and viruses. Autoantibodies do more work than antibodies by attacking the viruses as well as healthy tissue. When this happens inflammation, pain, and damage occurs to many parts of the body. Lupus is not a contagious disease that people should be afraid of. With some people, no visual changes happen, which means it is not noticeable to see someone with Lupus ("What is lupus?", 2016).

The organs that make up the lymphatic and immune system are the tonsils, spleen, thymus gland, lymph nodes, and lymphatic vessels. White blood cells (leukocytes), red blood cells (erythrocytes), plasma, and platelets (thrombocytes) make up the blood. Lymphocytes are leukocytes (white blood cells) that help the body fight off diseases. Two types of lymphocytes are B cells and T cells. Lymphocytes recognize antigens, or foreign substances/matter, in the body. Lymphocytes are a classification of agranulocytes, or cells (-cytes) without (a-) granules (granul/o) in the cytoplasm. B cells are created from stem cells, which are located in the bone marrow. B cells respond to antigens by becoming plasma cells. These plasma cells then create antibodies. Memory B cells produce a stronger response with the next exposure to the antigen. B cells fight off infection and bacteria while T cells defend against viruses and cancer cells. A hormone created by the thymus gland called thymosin changes lymphocytes into T cells. The thymus gland is active when you are a child and slowly shrinks, as you get older. T cells bind to the antigens on the cells and directly attack them. T cells secrete lymphokines that increase T cell production and directly kill cells with antigens. There are three types of T cells: cytotoxic T cells, helper T cells, and memory T cells.

Lupus “is predominantly a disease of young women (most commonly affecting women between the ages of 15–45) but can affect men as well” (Hughes & Sangle 2012). “Women of color (Asian and African American) are two to three times more likely to develop Lupus than Northern European women” (Hughes & Sangle 2012). It is a chronic autoimmune disease that affects many parts of the human body including the immune system, joints, skin, and organs within the body. Normally, the human body would produce proteins (antibodies) that protect the body from invaders such as viruses, bacteria and germs. In the human body afflicted with Lupus, the body becomes “autoimmune” and the body is unable to tell the difference between foreign invaders such as those named

As no lupus patients have similar symptoms, they don’t have an identical set of triggers. However, the common triggers include Stress, infection, sun exposure, or even seasonal flue. When you identify trigger within time, you can put in best efforts

The immune system (the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response) fails in the condition of lupus. Our immune system is what protects us from getting sick, it produces antibodies (a large number of proteins with higher molecular weight that are produced normally by specialized B cells after stimulation by an antigen

Lupus is a chronic inflammatory disease marked by its effect on various parts of the body, including the joints, skin, blood, and kidneys. It is a condition in which the body's immune system attacks its own cells and tissues, resulting in pain, inflammation, and often damage to organs. Lupus involves the immune system. The immune system makes antibodies that work to protect the body against foreign substances like viruses and bacteria. Such foreign bodies are called antigens. When a person has lupus, his or her body is unable to determine the difference between antigens and the individual's cells and body tissues. As such, the immune system creates antibodies against the individual's own tissues. These antibodies are called autoantibodies. Depending on the type of lupus, a wide range of symptoms may be experienced, from rashes, hair loss, and achy, swollen joints to fever, anemia, and abnormal blood clotting. Though the disease can affect many parts of the body, individuals usually experience symptoms in only a few organs. There is no known cure for lupus. However,