This experimental research is conducted to determine if there is any major change among two different types of vaccine, the shot and a nasal spray. Based on the given opinion, test was directed to observe the dissimilarity of the outcome and test the effectiveness of both. Using the information given 1000 participants were used dividing them into two groups of 500 each therefore “n will = 500, the number in one group when group sizes are equal” (Tanner, 2011). n1=500, n2=500, p1 = 0.16 the amount of participants who developed the flu, and p2= 0.24the proportion of the people who were treated with the nasal spray, and alpha= 0.05 the level of significance. Given these figures the hypothesis is defined either as a null hypothesis assuming that the shot and nasal spray are equally effective or assuming the shot is more effective than the nasal spray an alternative hypothesis will be used. With a Null hypothesis the average capacity of a population that uses the shot will be the same as the average capacity of a population that uses the nasal spray. The z test when using p as shared estimation of quantity = 0.20.Using the formula below: z = (p1-p2)/sqr+(p*1-p*(1/n1+1/n2) =0.16 – 0.24/0.025
= 0.08/0.025
= -32 p( z < -3.2)= 0.0008
P value = 0.0008< 0.05 (implication level) The null hypothesis is rejected at 5% of level of statistical significance . “When a result is statistically significant, the decision is to "reject the null hypothesis”(Tanner, 2011)." Results indicate
So, we should reject the null hypothesis H0. At a 0.05 level of significance level, we conclude that there is a significant difference between the average height for females and the average height for the males.
4) Discuss the implications of changing the level of significance to a larger value. What mistakes or error could increase if the level of significance in
Testing allows the p-value that represents the probability showing that results are unlikely to occur by chance. A p-value of 5% or lower is statistically significant. The p value helps in minimizing Type I or Type II errors in the dataset that can often occur when the p value is more than the significance level. The p value can help in stopping the positive and negative correlation between the dataset to reject the null hypothesis and to determine if there is statistical significance in the hypothesis. Understanding the p value is very important in helping researchers to determine the significance of the effect of their experiment and variables for other researchers
P-value represents a decimal between 1.0 to below .01. Unfortunately, the level of commonly accepted p-value is 0.05. The level of frequency of P>0.05 means that there is one in twenty chance that the whole study is just accidental. In other words, that there is one in twenty chance that a result may be positive in spite of having no actual relationship. This value is an estimate of the probability that the result has occurred by statistical accident. Thus, a small value of P represents a high level of statistical significance and vice
To test the null hypothesis, if the P-Value of the test is less than 0.05 I will reject the null hypothesis.
“Hypothesis testing is a decision-making process for evaluating claims about a population” (Bluman, 2013, p. 398). This process is used to determine if you will accept or reject the hypothesis. The claim is that the bottles contain less than 16 ounces. The null hypothesis is the soda bottles contain 16 ounces. The alternative hypothesis is the bottles contain less than 16 ounces. The significance level will be 0.05. The test method to be used is a t-score. The test statistic is calculated to be -11.24666539 and the P-value is 1.0. The P-value is the probability of observing a sample statistic as extreme as the test statistic, assuming the null hypothesis is true. The T Crit value is 1.69912702. The calculations show there is enough evidence to support the claim that the soda bottles do
Conclusion : Fails to reject the null hypothesis. The sample does not provide enough evidence to support the claim that mean is significantly different from 12 .
In the elderly (P), does the flu vaccine (I) compared to no vaccine (C) reduce the incidence of the flu (O) during flu season(T)?
With a P-value of 0.00, we have a strong level of significance. No additional information is needed to ensure that the data given is accurate.
The article, people should not be allowed to refuse vaccination by, Ronald Bailey. The thesis is, vaccines have declined the mortality and suffering caused by infectious diseases. The article mostly stresses how having vaccinations can save many peoples life. It also goes on to say peple who do not get these immunizations are free riding off the people who are vaccinated. However he does not have a very good arugment because he does not have all the facts to prove his argument. The general publicis going to die anyway, why not give them the choice to getvaccinated?
Working in the line of healthcare and prevention, we are encouraging people to get flu shots to help prevent them from getting the flu and it is the same with immunizations. There is a lot more to what we but to me this is an example of what Deming is trying to point out in what causes problems in quality. Technology, is one of the thing that is ever-changing in our workforce. Computer’s lifespan is approximately 5 years, and if we have employees using updated computer and other technology then essentially we are slowing down production. Therefore we have developed a plan to recognize that issue and have worked to be able to prevent that from happening by rotating site’s computers to be updated between 4-5 years, and for the computers not
First described by Karl Landsteiner, a hapten is a small molecule that can elicit an immune response only when it attaches itself to a larger carrier molecule, usually a protein creating the hapten-carrier adduct or hapten-carrier complex. This complex then has the ability to become immunogenic. Haptens react specifically to the antibodies created against it and while the hapten, alone, cannot cause antibodies to respond it, it can bind with antibodies and act as an antigen. An example of a substance acting as a hapten is penicillin. When administered as an antibiotic, penicillin can bind with proteins in the body to form a hapten-carrier complex and cause anaphylaxis. Another example is urushiol, a toxin found in poison ivy. During exposure, urushiol can bind with skin proteins creating a complex that then can cause dermatitis.
The results from this study only reflect a very small number of the population, so it is difficult for this experiment to show any significant results. It would have reflected better on the results if the sample size had been meet, however it was not possible due to lack of time and number of eligible volunteers.
As previously reviewed, penetration of substances in the skin is restricted by the SC which acts as a physical barrier, so the topical application of the vaccine formulation alone limits its transport across the skin and thus sufficient immune response is not achieved. Various physical approaches such as electroporation, iontophoresis, abrasions, tape stripping, sonophoresis, micro needles etc have been investigated to increase the penetration of substances across the skin by disrupting SC. Another approach to bypass the barrier function of SC is application of microneedles [53]. A microneedle array contains many micrometer-sized needles that can create a transport pathway large enough for proteins and NPs, but small sufficient to avoid harm [54,55]. Tape-stripping method has been shown to enhance cytotoxic T cell and cytokine immune responses upon subsequent application of various antigens and adjuvants to the skin in mice [56]. Similarly electrode preparation pads, emery paper, rubbing gauze or pumice on the skin removes cells by their abrasive effects and have been found to enhance immune responses in humans [57]. Mild hyperthermia with abrasion enhances transport of antigen into the skin, present it to LCs, migration of activated LCs to lymph nodes and trigger cascade of immune system.
The p-value is a measure of the strength of the evidence against the null hypothesis. The p-value is the probability of getting the observed value of the test statistic, or a value with the even greater evidence against Ho, if the null hypothesis is actually true. The smaller the p-value, the greater the evidence against the null hypothesis. If we have a given significance level, then we reject. If we do not have a given significance level, then it is not as cut-and-dried. If the P-value is less than (or equal to) α, then the null hypothesis is rejected in favor of the alternative hypothesis. And, if the P-value is greater than α, then the null hypothesis is not rejected. All statistical tests produce a p-value and this is equal to the probability of obtaining the observed difference, or one more extreme, if the null hypothesis is true. To put it another way if the null hypothesis is true, the p- value is the probability of obtaining a difference at least as large as that observed due to sampling variation. Consequently, if the p-value is small the data support the alternative hypothesis. If the p-value is large the data support the null hypothesis. But how small is ‘small’ and how large is large ‘?! Conventionally a p-value of 0.05 is generally regarded as sufficiently small to reject the null hypothesis. If the p-value is larger than 0.05 we fail to reject the null hypothesis. The 5% value is called the significance level of the test. Other significance levels that are