3- Endocrine Disease
Diabetes mellitus 19: Diabetes mellitus is a disease of glucose, fat & protein metabolism resulting from: Impaired insulin secretion, varying degree of insulin resistance, or both. Type I diabetes accounts for 5-10% of cases of diabetes, while Type II diabetes accounts for 80% of cases of diabetes in USA & UK Diabetes Mellitus is classified to primary and secondary diabetes, the primary diabetes is either20: a. Type 1 or Insulin Dependent DM (IDDM) b. Type 2 or non-insulin Dependent DM (NIDDM)
While secondary diabetes may be:
a. Pancreatic Disease.
b. Excess Endogenous production of hormonal antagonists to insulin.
c. Medication (Corticosteroids, thiazide
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Gestational Diabetes. Complications of Diabetes is divided into long term and short term complications, short term complications are hypoglycemia and diabetic ketoacidosis, while long term complications include peripheral neuropathy, retinopathy, nephropathy and cardiovascular diseases19.
Diagnosis of Diabetes mellitus20 :
• According to American diabetic association (ADA): Fasting blood sugar (FBS) > 126 mg/dl. Or post random blood sugar (PRBS) > 200mg/dl.
• Glycosylated Hemoglobin: Also termed hemoglobin A1C or HbA1c. it is a test to monitor the control of the diabetic patient over the previous 2 to 3 months. It measures the percentage of hemoglobin bound to glucose.
General manifestations of diabetes mellitus are Polyuria, polydipsia, polyphagia, weight loss and visual disturbance 21, while oral manifestations includes burning mouth, altered wound healing, increased incidence of infection, enlargement of the parotid glands and xerostomia and Neuropathy( paresthesia) gingivitis and periodontitis, attachment loss and alveolar bone loss is 3 fold compared to non-diabetic control subjects. Changes in the collagen metabolism and wound healing alternations. Periodontal infection increased the risk of poor glycemic control by six fold and oral Candida
If diabetes is not controlled, there are a lot of complications that can occur. It can result to cardiovascular diseases, kidney failure, loss of vision, respiratory infections, diabetic coma and a lot more. It is then important to follow the treatment regimen given to you strictly. It is also vital to know the different signs and symptoms of diabetes so that you will be able to get treated immediately. Further, you should know different diabetes recipes for better management of your
Hemoglobin A1c. Her number is concerning because it indicates that her blood sugar has been way too high over the past few months. The A1c is an indication of glycosylation in the body which is damaging to the blood vessels and peripheral nerves. It causes thickening of the basement membrane which will impair oxygen transport to the tissues and carbon dioxide removal.
Type 1 diabetes accounts for about 5 to 10 percent of diagnosed diabetes in the United States.
Most patients who have diabetes for an extended amount of time may end up with diabetic neuropathy, which is damage caused to the nerves; it affects the peripheral nerves, autonomic nerves, and focal nerves. From the high blood sugar, it can destroy parts of the patient’s blood vessels, heart, and kidneys. If diabetes is not treated, it will almost always cause heart disease or kidney disease.
"Diabetes mellitus is not a single disease but a group of disorders with glucose intolerance in common" (McCance 674). Diabetes mellitus is a metabolic disorder characterized by hyperglycemia (increased blood sugar) and results from defective insulin production, secretion, and utilization. There are many forms of diabetes. "Diabetes increases the risk of heart and blood vessel disease, amputation, infections, kidney damage, eye problems (including blindness), and nerve malfunction" (Husain). I will
*Endocrine glands produce – hormones, they work with other hormones to perform many functions including: control water & electrolyte balance, regulating carbohydrate metabolism, working as neurotransmitters, maintaining stress & inflammation, regulate reproductive functions
Over twenty-nine million Americans suffer from this disease. If not treated, some of the possible complications of diabetes include: kidney damage, heart and blood vessel disease, eye damage, and nerve damage. The most common types of this disease are type one diabetes and type two diabetes. Type one diabetes is usually diagnosed when people are children and young adults.
. It also proves to be fatal due in part to the development of other complications or conditions. Complications include, nerve disease, nonalcoholic fatty liver disease, periodontal (gum) disease, hearing loss, erectile dysfunction, depression, and complications of pregnancy and many others. People with diabetes have higher rates of death due to cardiovascular disease and higher rates of hospitalization for heart attacks and stroke. Diabetes is a leading cause of kidney failure, retinopathy, and nontraumatic lower limb amputations (CDC,
If left untreated, diabetes can cause many problems in the long run. Many of the complications can include diabetic ketoacidosis, nonketotic hyperosmolar coma, or death. Serious long-term complications include heart disease, stroke, chronic kidney failure, foot ulcers, and even damage to the eyes. In addition to the known ones above, these are the main symptoms, blurry vision, headache, fatigue, slow healing of cuts, and itchy skin. Prolonged high blood glucose can cause glucose absorption in the lens of the eyes, which most likely leads to changes in its shape, resulting in vision changes. Many skin rashes that can occur in diabetes are collectively known as diabetic
Diabetes is associated with an increased risk of developing primarily vascular complications that contribute to morbidity and mortality of diabetic patients. Poor glycaemic control leads to vascular complications that affect large (macrovascular), small (microvascular) vessels or both. Macrovascular complications include coronary heart disease, peripheral vascular disease and stroke. Microvascular complications contribute to diabetic neuropathy (nerve damage), nephropathy (kidney disease) and retinopathy (eye disease).
Diabetes mellitus (DM) is a condition in the body that is related to a faulty metabolism. It means that the body’s metabolism is not functioning properly, which leads to adverse effects in the health. The food we ingest, gets broken down into blood sugar (glucose), which is what fuels our body in the form of energy. This converted glucose needs to enter our cells so that it can be used for energy and growth. And in order for the glucose to enter our cells, there needs to be insulin present, which the beta cells of the pancreas is responsible for producing. This hormone is responsible for maintaining glucose level in the blood. It allows the body cells to use glucose as a main
Long-term effects of diabetes can cause many serious complications: heart disease, stroke, blindness, amputations, and kidney disease and nerve damage. These complications are usually progressive and develop over time due to poor control of blood glucose levels. High blood glucose levels cause a narrowing of all the vessels, blockage, and high blood pressure.
Type 2 diabetes is a very well known disease throughout the US. There are about 27 million people in the US with the disease and 86 million others have prediabetes which means their blood glucose is not right but also not high enough to be diabetes yet. 208,000 people under the age of twenty have been diagnosed with either Type 1 or 2 Diabetes.
Diabetes is split into two types, Type 1 and Type 2. Type 1 is the more severe of the two
Diabetes Mellitus is “a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is a disease which is caused by the insufficient insulin secretion or decrease in the peripheral effects of insulin. It is a serious problem in terms of morbidity and mortality. The hyperglycemia is associated with long term damage, dysfunction and failure of various organs especially the eyes, kidneys, nerves, heart and blood vessels. It’s associated with many complications which includes blindness of the eyes and amputations of the extremities. It is also associated with neuropathy, retinopathy, and cardiovascular diseases which lead to mortalities.