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Endocrine Disease Outline

Decent Essays

3- Endocrine Disease
Diabetes mellitus 19: Diabetes mellitus is a disease of glucose, fat & protein metabolism resulting from: Impaired insulin secretion, varying degree of insulin resistance, or both. Type I diabetes accounts for 5-10% of cases of diabetes, while Type II diabetes accounts for 80% of cases of diabetes in USA & UK Diabetes Mellitus is classified to primary and secondary diabetes, the primary diabetes is either20: a. Type 1 or Insulin Dependent DM (IDDM) b. Type 2 or non-insulin Dependent DM (NIDDM)
While secondary diabetes may be:
a. Pancreatic Disease.
b. Excess Endogenous production of hormonal antagonists to insulin.
c. Medication (Corticosteroids, thiazide …show more content…

Gestational Diabetes. Complications of Diabetes is divided into long term and short term complications, short term complications are hypoglycemia and diabetic ketoacidosis, while long term complications include peripheral neuropathy, retinopathy, nephropathy and cardiovascular diseases19.
Diagnosis of Diabetes mellitus20 :
• According to American diabetic association (ADA): Fasting blood sugar (FBS) > 126 mg/dl. Or post random blood sugar (PRBS) > 200mg/dl.
• Glycosylated Hemoglobin: Also termed hemoglobin A1C or HbA1c. it is a test to monitor the control of the diabetic patient over the previous 2 to 3 months. It measures the percentage of hemoglobin bound to glucose.

General manifestations of diabetes mellitus are Polyuria, polydipsia, polyphagia, weight loss and visual disturbance 21, while oral manifestations includes burning mouth, altered wound healing, increased incidence of infection, enlargement of the parotid glands and xerostomia and Neuropathy( paresthesia) gingivitis and periodontitis, attachment loss and alveolar bone loss is 3 fold compared to non-diabetic control subjects. Changes in the collagen metabolism and wound healing alternations. Periodontal infection increased the risk of poor glycemic control by six fold and oral Candida

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