Factors Affecting The Cell And Anaerobic Glycolysis

952 WordsOct 17, 20154 Pages
A. NADH is an electron transporter that shuttles electrons from substrates to the mitochondrial electron transport chain. how might allosteric control of glycolytic enzymes be used as a mechanism that could create oscillations in NADH? (5 pts) The glycolytic enzyme produces two molecules of ATP and NADH from pyruvate. The allosteric control of the glycolytic enzyme are controlled by the amount of NADH produced. The higher concentration of NADH, will lead to more electrons being contributed to the electron transport cycle, increasing the hydrogen ion gradient, which leads to a increase production of ATP. The increased production of ATP will cause the allosteric control enzyme to slow down the production and cause ADP to increase. This will allow allosteric control enzymes to oscillate due to the lag in the cycle. This large feedback loop is controlled by the ATP. This loop will cycle twice in order to create an oscillation, one NADAH reaches a maximum, the other NADH reaches a minimum. B. Why might this control mechanism involve both aerobic and anaerobic glycolysis? Cytoplasmic NADH and. mitochondrial NADH: Which would show greater swings in oxidation-reduction state and why? Propose a way in which you could experimentally observe this. (5 pts) This control mechanism may involve both aerobic and anaerobic glycolysis because they were in in parallel and in the same way. They both involve the same product of ATP, which then can be controlled by
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