Group B Streptococcus Agalactiae

782 WordsDec 6, 20154 Pages
Group B Streptococcus agalactiae is an important Gram-positive bacterial pathogen that cause a wide variety of clinical infections, ranging from septicemia to meningitis. The reported lethality of severe S. agalactiae infections is ranging from 4 to 6% in the United States. Of note, it has been suggested that the incidence of neonatal disease is considerably greater than reported, because the requirement for positive cultures from blood or cerebrospinal fluid may underestimates the true burden of disease. Therefore, in this review I focused on virulence factors of S. agalactiae in order to elucidate aspects of the infection. S. agalactiae is frequently colonizes rectovaginal tract. S. agalactiae is found in 15-40% of adult women, and there is a 1% chance to be transmitted vertically from mother to infants before or during birth. This type of infection is divided into early-onset and late-onset infections. Early-onset infection, is one of the most common infection among neonates with a mortality rates of 4 to 6% in the United States. This type of infection is characterized with shock and breathing difficulties and occurs at birth or within the first 6 days of life. This infant probably had become infected by ascending spread of the organism from the maternal genital tract to the amniotic fluid, in which the bacteria colonize and multiply within the respiratory tract of the fetus and causes pneumonia. Also, this bacteria may enter the respiratory tract and spread to the
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