HIV
It has been three decades since the discovery of the Human Immunodeficiency Virus, HIV, which is shockingly one of the few viruses that is incurable. Since being first recognized there has been extraordinary advances in understanding the virus, possible treatments, and prevention. Decades of studying the virus has directed researches toward treatments that help people living with HIV live sustainable lives. Most importantly, is the search for an end to this epidemic through controlling and ultimately ending HIV and an eventual AIDS. AIDS researchers are aggressively pushing 3 key areas of research. First, finding the actual amount of people infected with HIV through voluntary tests and pressing the important of ART (antiretroviral treatment), the only treatment for a sustainably living with HIV. Second, researches are trying to find a cure for HIV which would eliminate the need for lifelong ART. Lastly, preventing any more infections, considering HIV has infected 2.6 million people annually. (Dieffenbach, C. W., Fauci, A. S. 2011)
The biology behind the virus has improved and affected the understanding of the virology of the virus such as the viral entry, gene expression, and mechanism of the virus that is able to manipulate the host cell to replicate. One of the interesting aspects of the HIV life cycle that caught researcher’s eyes is the generation of the new HIV particles stemming from the infected cells.
The Gag (Group specific antigen) protein for HIV is
Dan McClain is a sheriff in Scott County Indiana who opposed needle exchange programs until there was a surge in human immunodeficiency virus (HIV) outbreaks that were directly influenced by the drug Opana. The Centers for Disease Control and Prevention (CDC) linking a HIV outbreak to Opana usage within Scott County in Indiana causes the need for extreme attention to this prescription pill. In March of 2011 Scott County experienced eight new HIV cases, and just two months later that number had increased to 81 new cases, causing a significant concern for Dan McClain. He is sheriff within Scott County and wanted to know how he could quickly intercept the worst HIV outbreak Indiana had ever experienced. The untimely involvement of Opana’s in
The Human Immunodeficiency Virus, also known as HIV, was discovered by Dr. Robert Gallo and Dr. Luc Montagnier. HIV had its first known case in a human in the year 1959. Though, its first known case in the United States was in 1981 when the Center for Disease Control and Prevention, known as the CDC, reported five homosexual men in Los Angeles, California with Pneumocystis Carinii Pneumonia, a rare form of pneumonia. These findings were published in CDC 'S Morbidity and Mortality Weekly Report, or MMWR, which is read by physicians around the world. Soon after, The New York Times reported that 41 homosexual men had been diagnosed with a rare cancer called Kaposi 's Sarcoma. Since this disease was only spreading amongst gay men at the time,
Over the last three decades, the Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Disease (AIDS) epidemic has been a public health concern in the United States (US) and globally. Centers for Disease Control and Prevention [CDC], (2015d) estimates that in the US, over 1.2 million people are living with HIV, of which 12.8% are unaware of their diagnosis. Due to exceptional medical advances in treatment and prevention strategies, a healthier quality of life and longevity can now be achieved with persons diagnosed with HIV (Irvine et al., 2014; CDC 2015a; Sayles, Wong, Kinsler, Martins, & Cunningham, 2009). However, despite the advance from a deathly diagnosis to a chronic disease, the continuum of care in treatment is still threatened.
The human immunodeficiency virus (HIV) that causes AIDS (auto immunodeficiency syndrome – the final stage of HIV) can be classified as one of the most devastating epidemics in United States history (Centers for Disease Control and Prevention [CDC], 2015). Although still an alarming concern in public health, due to prevention strategies and medical advances, the disease is less fatal and is treated as a chronic disease (instead of a death sentence, as in the past). There are currently 1.2 million people living in the US with HIV (CDC, 2015). The highest rates transmitted through sexual intercourse or injection drug use through the exchange of bodily fluids (CDC, 2015). It is estimated that 25% of those living with HIV are women, and only
The Human Immunodeficiency Virus is a retrovirus originally encoded in ribonucleic acid or RNA (Fraser et al., 2008). HIV virions travel through the blood stream and other bodily fluids in order to infect
Human immunodeficiency virus (HIV) has become more commonly seen in the world. It is important to show compassion rather than judging that patient based on a virus. The hygienist plays an important role in making the patient feel comfortable and in a judgment free environment. The patient should not feel as if the disease or virus defines the overall character of the patient. Standards precautions are still the same when treating all patients with or without a compromising disease or virus. However, the hygienist should be aware of future signs and symptoms of the oral cavity due to HIV. Education on awareness will allow the hygienist to provide certain treatment to that particular patient to increase comfort and prevent further irritation.
The first Human Immunodeficiency Virus (HIV) showed up decades ago, as far as we know. However, there could have been many more infections over the years that were either recorded as unknown cases or got called with a different disease name. Nevertheless, humans have been trying to understand how this tricky virus work and what strategies they can use to prevent or cure the virus. Since it can mutate and adapts so quickly, finding a cure or an antivirus is a challenging task. Therefore, this paper will discuss some of the strategies that are being used to develop a vaccine against this virus, including: strategies that can be done before a person is infected, strategies for immediately after infection, and complete cures.
Adults are not the only population affected by human immunodeficiency virus (HIV). Children are also affected by this virus. According to the Center for Disease Control and Prevention (2013), in the United States, there is more than a 90% decline in children who are infected with HIV prenatally since the mid-1990s. This is due to HIV testing and preventive interventions. The most common route of HIV infection in children is through perinatal transmission. Perinatal transmission is when a mother passes the infection to her baby. This transmission is through labor and delivery, breastfeeding, or during pregnancy (CDC, 2013).
HIV (Human immunodeficiency virus) is a lentivirus that results in AIDS (acquired immunodeficiency syndrome). HIV attacks and destroys CD4 helper lymphocyte cells - a specific type of immune system cell. As a result, the body has a harder time fighting off other infections, making minor illnesses more severe. The virus will go further to use those CD4 cells to create more of the virus. Once so many CD4 cells have been destroyed, HIV will become AIDS.
Societies have been devastated by a number of epidemiological outbreaks, but few diseases have been as antagonistic as the human immunodeficiency virus (HIV). The global transmission of this disease has been perpetuated by the ease of long distance travel and immigration (Magis-Rodriguez, 2004; Xu et al., 2014). Throughout the past 35 years the course of HIV and other sexually transmitted infections (STIs), as well as patterns of immigration, have changed immensely. Given the increase in both HIV and immigration, specifically in North Carolina (NC), this dissertation will focus mostly on changes, concerns, and strengths pertaining to the screening and treatment for HIV among Latino immigrants in NC. The
HIV infects CD4 + T cells. The viral particles of HIV keep their genetic information stored as double-stranded RNA. They use a reverse transcriptase that converts their genome into double-stranded DNA (Edina, Misawa, Kanemura, Koyanagi, 2013). During this process the virus can mutate quickly because many errors occur in the HIV genome. “The DNA is inserted into the host cell genome by integrases which use LTR (long terminal repeat) sequences on the viral genome to integrate with the host DNA” (Ebina, Misawa, Kanemura, Koyanagi, 2013). This results in a provirus that can continuously produce new viruses that infect other immune cells.
HIV, the Human Immunodeficiency Virus, was first discovered by CDC in 1981 [3], then described as HTLV-III in 1983 and was later changed into its current name. Ever since its emergence, this virus has caused millions of infections throughout the world, with most of the cases originating in the African region [1]. This retrovirus has made it difficult in the past for scientists to treat it since it changes its RNA once inside the cell to DNA, through the enzyme reverse transcriptase, and keeps changing its genetic information making it difficult to target a specific genome. The main concern of HIV is the development into AIDS, Acquired Immunodeficiency Disorder, which targets the body’s own T-cells through targeting the CD4 and co-receptors leading to various opportunistic infections and, eventually, death.
Only a few diseases in modern history have been so devastating and impose a direct global public health threat to be referred to as “The modern plague” [1, 2]. The Human immunodeficiency virus (HIV) is considered to be the causative agent of one of the deadliest pandemics our generation have witnessed collecting over 30 million lives worldwide since the 1980s [3], with 3.4 million children under the age of 15 living with the virus as of 2012 [4]. In 1983, HIV has been linked to the acquired immunodeficiency syndrome (AIDS) by Robert Gallo and his collaborators in a series of four papers published in Science magazine [5, 6]. Since then, research has been targeting
The Human Immunodeficiency Virus (HIV) is an immune system disorder that can be contracted through sexual activity as well as other types of contact. (Healthy Living, pg. 79) If left untreated this virus can turn into AIDS (Acquired Immunodeficiency Syndrome). AIDS is the final stage of the Human Immunodeficiency Virus (HIV). (aids.gov) AIDS is an incurable progressive disease that causes gradual destruction of CD4 T cells by the human immunodeficiency virus (HIV). (Diseases, pg. 431) A healthy adult has a CD4 T cell count of 1,000 or more but a person suffering from HIV could have a count lower than 200. CD4 T cells are crucial to the immune system; without them the immune system would not have the ability to fight off infections.
Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) continues to be an incredibly important health concern for not only the United States (US) but across the Globe (Centers for Disease Control and Prevention [CDC], 2016a). In the US alone, there are an estimated 1.2 million people that as of 2013 are living with the disease (CDC, 2016a). Scientists believe that HIV derived and mutated from a virus known as the Simian Immunodeficiency virus which was prevalent in chimpanzees, during a time that humans were hunting and consuming chimpanzee meat (CDC, 2016a).