What is DNA? DNA (Deoxyribonucleic) is a molecule that contains the instructions an organism
needs to develop, live and reproduce. DNA is made up of nucleotides; every nucleotide has a phosphate
group, a sugar group and a nitrogen base. The four types of nitrogen bases are adenine (A), thymine (T),
guanine (G) and cytosine (C).These four bases determine the DNA genetic code. All four nucleotides are
made by sticking a phosphate group and a nucleobase to a sugar. The sugar in all four nucleotides is
called deoxyribose. It’s a cyclical molecule; most of its atoms are arranged in a ring-structure. The ring
contains one oxygen and four carbons. A fifth carbon atom is attached to the fourth carbon of the ring.
The phosphate group is a phosphorous
Fragment 7 is shown in the structure. Electron density map suggested two bulk electro-rich group present in the fragment, which corresponds to the two ring structure on 7. The heterocyclic ring has high e-density and forms a hydrophobic interaction with Leu144 residue. The e-rich NH2 group on this ring
2. Using the atom and bond library below, construct the following molecule. It may be
The nucleotides encompass a sugar molecule (2' deoxyribose), one among four element ring structures called bases (called A (A), purine (G), pyrimidine (C) and T (T)) and a phosphate cluster.
o The parent alkane is the longest carbon chain to which an –OH group is attached
In UNIT 7 you learned about the basics structure as well as the basic functions of deoxyribonucleic acid. You learned that deoxyribonucleic acid carries an “instruction manuel” to produce proteins that are responsible for passing traits from your parents to you. As you demonstrated in the previous activity, deoxyribonucleic acid is made of four nucleotides base pairs: adenine, thymine, cytosine, and guanine. They are often abbreviated as A, T, C, and G. The uniqueness of deoxyribonucleic acid is not particularly in just these 4 subunits, but how they are arranged. In this activity you will recreate protein synthesis.
Purine: Consists of a pyrimidine ring fused to an imidazole ring. It is the most widely occurring nitrogen-containing heterocycle in nature. A building block for nucleic acids, specifically nucleobases Adenine and Guanine.
DNA(deoxyribonucleic acid) is a molecule that carries the instructions for reproduction, growth, development, and functioning for all known living organisms.
But when it comes to base-pairing rules in RNA, Adenine (A) is paired with Uracil (U) instead of Thymine (T), and Cytosine(C) is paired with Guanine (G). Figure __ illustrates the transcription of DNA sequence into the mRNA codons. It also shows the transfer RNA (tRNA) anticodon that is complementary to mRNA codon
DNA is found inside the nucleus of cells. It has two complementary, antiparallel strands. The strands contain nucleotides, which each have a phosphoric acid, deoxyribose sugar and a base. There are two groups of bases purine and pyrimidine; adenine and guanine are purine bases, and cytosine and thymine are pyrimidine bases. A purine must pair with a pyrimidine, a purine can’t pair with another purine nor can a pyrimidine pair with another pyrimidine, this is in order to ensure that the ‘rungs in the ladder’ remain the same width. The two strands are bonded together through hydrogen bonds between the corresponding bases; adenine and thymine pair together with two hydrogen bonds, and guanine and cytosine pair together with three hydrogen bonds.
DNA has two types of bases, these are known as purines and pyrimidines. Purines are adenine and guanine and the pyrimidines are thymine and cytosine. Purines are double ringed structures whereas pyrimidines are a single ring structure. Adenine is complementary to thymine and cytosine is complementary to guanine. Due to the different complementary base pairings within the two groups it allows information to be transcribed. In between the different bases there is hydrogen
This makes DNA more stable compared to RNA. The rungs of the double helix are molecules called nucleotides and the rails consist of sugar and phosphate molecules. In our body DNA is responsible for storing and transferring genetic information and its base pairing uses adenine, thymine, cytosine, and guanine.
Hereditary material in humans is contained in our DNA. DNA is a double helix structure of deoxyribonucleic acid comprised of four chemical bases: adenine (A), guanine (G), cytosine (C), and thymine (T). Adenine forms hydrogen bonds with thymine and cytosine forms hydrogen bonds with guanine. The polypeptide strand is held together by covalent bonds. RNA is ribonucleic acid, a nucleic acid essential to coding, decoding, and regulation of gene expression as well as protein synthesis. RNA is so vital to these functions because, unlike DNA, it can leave the nuclear envelope. Like DNA, RNA is comprised of four chemical bases: adenine (A), uracil (U), guanine (G) and cytosine (C). In addition to one base being different, RNA and DNA contain different sugar molecules. RNA is comprised of ribose and DNA is comprised of deoxyribose, hence the names. RNA is transcribed from DNA. DNA and RNA are essential in the production of protein. Proteins are distinctly folded amino acid sequences dictated by the nucleotide sequences of its genetic material. Proteins carry out specific functions within the cell such as catalyzing chemical reactions, receptors and offering structure in the form of collagen or elastin for example.
Deoxyribose nucleic acid, which is essentially known to be the genetic information carrier for most organisms, is a double helix structure that is created by a sugar-phosphate backbone that fastens base pairs onto it. These bases, which are adenine, guanine, thymine, and cytosine, are what make up the genetic code stored within the DNA when they pair up with each other. The amino acid sequence in protein synthesis is ultimately decided by the sequence of the four nitrogenous bases. As a result, the sequence of the nitrogenous bases is what determines an organism genetic code. In order to form base pairs, Adenine pairs up with Thymine, while Guanine pairs up with Cytosine. In addition to pairing with each other, these bases also pair up with a phosphate group and deoxyribose sugar. When these three come
All living organisms, from amoebas to humans, have a molecular code called DNA in their cells, which instruct the activities that keep the organism alive. DNA is made up of long, twisted strands of four molecular “letters” (A, T, G, and C), which pair up according to their complementary base pairs, and their order determines how proteins — the vital molecules that perform all the major tasks in our cells — are made. (Refer to Diagram 1 to help sum up the concept.)
DNA is composed of nucleotides that are made up of only four nitrogen bases; A, T, G, C, adenine, thymine, guanine and cytosine respectively. The engagement of these nucleotides in a particular sequence forms a gene. Interaction of genes forms chromosomes, which are the form in which hereditary information will be passed from generation to generation. However, depending on the type of species hereditary information is passed in either reproducing sexually or asexually. Both these types of reproduction yield offspring