Infectious agents, such as bacteria and viruses, represent the third largest cause of cancer. Accounting for more than 20% of all cancers worldwide, cancers caused by infectious agents are more common in developing countries where access to medicine and antibiotics is more difficult. However, even in developed countries like the United States, infections still play a role in many common cancers, some which have proven difficult to treat.
Infections that are carcinogenic, such as Hepatitis C and HIV, all share similar characteristics. These hallmarks include their ability to induce persistent inflammation, which can lead to changes to immune cells, and their ability to suppress the immune response, which impedes the immune system’s ability to fight off cancerous cells. Another way some infections, especially viruses, can cause cancer is by directly changing the DNA of their host by inserting their own genomic material into cells. When this happens, innate cancer-fighting mechanisms, like apoptosis, can be hindered. This can lead to the uncontrolled
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Many viruses can cause persistent infections by establishing niches, making them extremely difficult to treat. An example is Human Immunodeficiency virus (HIV), which has been shown to increase a person’s odds of developing several different types of cancers, such as anal cancer, Hodgkin disease, lung cancer, and even skin cancer. HIV is known for establishing persistent infections and for its inability to be cured. Additionally, symptoms of HIV often emerge months after infections, which can lead to extensive damage of the immune system, a disease called Acquired Immunodeficiency Syndrome (AIDS). Because of this, having HIV greatly increases a person’s risk of getting several different types of cancer as the immune system cannot recognize and target cancerous
HIV or the Human Deficiency virus is like other viruses including the flu, but the one thing that makes this virus so different than any other is that the body is unable to clear this one out completely. Once someone is infected, there is no cure. Over time, HIV can also hide or mask itself in the body's cells. The cells within a person's body that fight off infection are called CD4 cells or T cells. HIV attacks these cells and copies or replicates itself inside these cells, then destroys them. HIV over time will destroy so many of these cells that the body is unable to fight off infection anymore. When this starts happening, AIDS or Acquired Immunodeficiency Syndrome happens which is the final stage
Some cancers can be caused by infections with pathogens. Notable among these include liver cancers due to Hepatitis B and C infections; cervical cancer due to infections with Human Papilloma virus (HPV); Epstein Barr virus causing Burkitt's lymphoma and gastric or stomach cancer due to Helicobacter pylori infection.
A few cancers can be brought on by contaminations with pathogens.Some among these incorporate liver diseases because of Hepatitis B and C contaminations; cervical growth because of contaminations with Human Papilloma infection ; Epstein Barr infection bringing about Burkitt's lymphoma and gastric or stomach cancer because of Helicobacter pylori disease.
Cancer can be caused by a plethora of things, i.e. mutation through viruses, chemical or radiations, carcinogens. Mutation, a type of evolution, is any change in the nucleotide sequence of a cell’s DNA (Reece 199), this may come about by having a virus, exposure to certain chemicals and radiation, after the mutation, there is no reversing it and hence can be transferred genetically to any children. A carcinogen defined by Encyclopedia Britannica is, “any of a number of agents that can cause cancer in humans,” which leads to mutation. After
People think viruses are able to trigger cancer if someone was to be infected with a virus. Cancer is defined by Oxford’s dictionary as “ the disease caused by an uncontrolled division of abnormal cells in a part of the body”. While a virus is defined by Oxford as, “an infective agent that typically consists of a nucleic acid molecule in a protein coat...and is able to multiply only within the living cells of a host”. Furthermore, a virus carries a single strand of Ribonucleic Acid (RNA). This acid is a polymeric molecule implicated in various biological roles in coding, decoding, regulation, and expression of genes (“RNA”).
The uses of viruses to treat cancer have been talked about since the 1900’, but only due to the recent advances in microbiology, immunology, and virology, have we been able to understand how it reduces the size of cancerous tumors. One of the earliest recorded cases of viruses killing cancer was in 1896. A 42-year-old woman just recovering from influenza, when the doctors realized that her cancer was going into remission.
One thing I learned in researching cancer is that in order for cancer to appear in our body it has to avoid being detected by our immune system. The cancer cells have to avoid being detected by the immune system because if they are detected the immune system will try and fight off the abnormality. If your immune system does not detect the abnormality in cells, the cancer cells will grow and reproduce causing cancer to spread rapidly. The cancer cells that are not detected they can create colonies and spread rapidly.
Cancer stands to be the most prominent causes of death in economically developed countries and the second leading cause of death in developing countries. Cancer often comes from the materialization of a tumor because of a gene mutation. When a gene mutates it could allow rapid growth, fail to stop uncontrolled cell growth, or make mistakes when repairing DNA errors. If any of these mutations occur, it will cause the cell to grow and divide more rapidly. This creates many new cells that all have a constant mutation. Tumors form in the body when cells are produced uncontrollably, meaning that new cells are produced when they are not desired, and then they cluster together to create a tumor. Tumors can either be benign, which means that it is non-cancerous, or it can be malignant, which means that it is cancerous. If cells break off from a malignant tumor, they will enter the bloodstream, and spread throughout the body.
Most diseases come from a pathogen that invades the body, that targets the body specifically, looking for nothing but to wage war. Cancer is different; it comes from inside the body. If infections are a war, cancer is a misunderstanding. Cancer is an overgrowth of regular, human cells. The cells on their own are not harmful, you have billions of others just like them. The problems begin to emerge when too many cell form into a tumor. These tumors, and they grow, begin to interrupt necessary bodily functions. If a tumor forms in the heart of the brain, then that extra mass can interrupt with that vital organ’s function. If it forms in your digestive system, the body can’t metabolize food. It forms in the lungs and the body is rendered unable to breathe (USCB Science Line). This is how cancer
Some cancers can’t be avoided. Some cancers come from decisions we make, such as lung cancer. There are only three main causes of lung cancer: cigarette smoking, tobacco, and second-hand smoking. Of course there are other ways, though cigarette smoking, alone contributes to 80 to 90% of lung cancer patients. Many doctors have tried to understand how breast cancer is caused, but one thing they do know is breast cancer is caused when there is damage to a cell’s DNA. Prostate cancer is also difficult to pin-point a cause. Basically there is a change in the cell’s DNA.
There has been a spontaneous advancement in the understanding the pathogenesis of cancer over the last two decades. Even though there has been a significant success in the knowledge of tumor, there still a wide gap in the treatment of tumors. There is a little treatment information available on cancer making it difficult to control it. Chemotherapy remains the only effective treatment method used. This study aims at examining the possible roles of the p53 gene in leukemia and how that data can be utilized for diagnosis and treatment of cancer.
Cancer disease imposes a global threat to public health. Epidemiological data clearly show an increase of cancer diffusion over the world every year. Moreover to genetic factors that are crucial for cancer formation and development, environmental factors are important for its progression and advanced. These include lifestyle as tobacco smoking, alcohol drinking, physical activity, industry and microbial factors as radiation, pollution, infection and diet
Cancer is a tragedy that has affected families around the world for thousands of years. This disease has been a mystery, until recent discoveries have begun to unravel its origins, treatments, and causes. Cancer is important to understand because it’s vast impact on the world today. There are ways to lower the chances of getting cancer as well as removing it. Anyone is capable of getting cancer but the three main factors that can cause it is genetic traits, life choices, and environmental surroundings.
Though viruses may seem as though it only has the potential to cause harm, recent studies have surfaced to change its bad reputation. Common known viruses such as Ebola, rabies, influenza, HIV and more are known to show harmful reactions to humans, sometimes even possible to cause death. Because of the way they work, viruses such as the human immunodeficiency virus has been looked into in terms of reprogramming, ending in a result that could possibly be an option to treat another catastrophic epidemic of humans, cancer.
The presence and outbreak of an infectious disease can have global consequences. Such consequences include the deaths of many people due to an inability to contain the disease. When an infectious disease spreads to, and affects, different populations, this is known as a pandemic. One pandemic that has had far reaching consequences is that of HIV (human immunodeficiency)/AIDS (acquired immune deficiency symptoms), which officially began in 1981 and since has taken the lives of over 39 million people worldwide (PBS). The HIV virus attacks one’s “T-cells,” which are vital to one’s immune system. Someone infected with the virus becomes increasingly susceptible to contracting