preview

Increased Incidence Of Obesity, Diabetes, And Metabolic Syndrome

Good Essays

Increased incidence of obesity, diabetes, and metabolic syndrome, coupled with heightened consumer awareness, has led to unfaltering movement toward the utilization of low calorie artificial sweeteners which make artificial them progressively prevalent as an alternative to sugar. These artificial sweeteners, also called nonnutritive sweeteners (NNS)/low calorie sweeteners/intense sweeteners, provide more intense sweetness and no or a few calories per gram and are used in beverages, dietary products, drugs, and even mouthwashes. The United States Food and Drug Administration (US-FDA)authority has approved six NNS (saccharine, aspartame ,sucralose, neotame , acesulfame K, and stevia) for use in humans and has classified them under generally recognized as safe (GRAS) category.(Sharma et al. ,2016).

Sucralose(1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-chloro-4-deoxy-α-D-galactopyranoside; is made by substituting three hydroxyl groups of sucrose with chlorine atoms. Replacing three of the hydrogen atoms in the sucrose molecule with chlorine atoms makes sucralose almost non absorbable by the intestine, thereby not increasing the intake of calories in the food ingested. Its importance is based mainly on properties such as its sweetness, immunity to metabolic degradation, non-hygroscopic nature, and relative heat resistance. It has a taste profile very similar to that of sugar without any aftertaste and is approximately 600 times as sweet as sucrose(Idris et al., 2013).
Despite

Get Access