Introduction
Canine diabetes has become a common health concern in recent years, affecting twenty-two to forty percent of the canine population globally (German, 2006). Dogs diagnosed with diabetes are typically classified as insulin-resistant or insulin-deficient, these two categories are commonly referred to as type 1 diabetes. The difference between the two main types of canine diabetes is the body’s inability to respond to insulin, insulin-resistant, or the inability to produce insulin, insulin-deficient. Presently, there is no evidence of type 2 diabetes in the canine model (Short et al., 2009). Type 2 diabetes is the most common type to affect humans and is often a result of obesity. Type 2 DM can be managed through diet and avoid
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Evidence uncovered by research focused on the genetic markers of diabetes mellitus shows different genetic markers depending on the breed of dog. Genetic markers are also influenced by the specific type of diabetes (Short et al., 2009). That is to say a dog with insulin-deficient diabetes may have a different allele altered than a dog with insulin-resistant diabetes. There is some evidence that certain dogs could have a genetic trait which produces antibodies to the naturally occurring b-cells. When this occurs, the body’s white blood cells are destroying the b-cells or the insulin that binds to the b-cells preventing the uptake of insulin (Rand et al., 2004).
According to collected data from numerous studies, some breeds are considered to be at-risk for diabetes (Catchpole et al., 2005, German, 2006, Short et al., 2009, Rand et al., 2004). This corresponds with the information gathered concerning genetic predisposition for diabetes; it is logical for a particular breed with a particular affected allele would have a higher prevalence of diabetes than those breeds in which a genetic marker for diabetes is not present. The breeds most likely to develop diabetes are: Cairn Terriers and Samoyeds are the most likely breeds to develop diabetes. Miniature Poodles, Collies, King Charles Cocker Spaniels, and Schnauzers are at a slightly elevated risk. Labradors, German Shepard’s, and mixed breeds do not
The use of Diabetic Alert Dogs to manage blood sugar levels in Type 1 Diabetic Children
We dog owners know the responsibility that exists in taking care of our pets. We have to make sure to keep track of nearly everything so that they keep on living and thriving healthily in everything they do. But sometimes the safety measures aren’t enough, and a disease like canine diabetes catches you and your pet unawares. I’ve heard of it happen before—your responsibility doubles, and now the overall treatment of your dog is in your hands (and sometimes, in your vet’s hands). In order to treat your dog’s diabetes, you need to know everything you can to do your job properly. Your homework, of course, will depend on your dog’s specific condition and needs.
Diabetes mellitus (DM) is a pandemic that affects millions of people. The growth rate of unrecognized pre-diabetes in America is expected to rise up to 52% by 2020 (Lorenzo, 2013). As the prevalence of diabetes increases, so will the complications and burden of the disease. One of the leading causes for cardiovascular disease, renal failure, nontraumatic lower limb amputations, stroke, and new cases of blindness is DM (Lorenzo, 2013).
Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while
An overview of the proposed sequences of the key pathological features of type 2 diabetes is provided by Dr. Jack Leahy from the University of Vermont College Of Medicine. In his article he addresses the need for continued genetic research since little discovery has been made in this area. He also explains the known environmental causes such as sedentary lifestyles and high fat diets that contribute to type 2 diabetes, changes in lifestyle practices would reduce the incidence of this disease but this is not a practical solution. The best solution according to Dr. Leahy lays in understanding the
Type two diabetes is the most common disease today, and it has a great impact on the lives of many people in the United States. Type two diabetes results when the body is resistant to insulin or impaired secretion of insulin by the pancreatic beta cells. The pancreas produces too much insulin, but over time it is not able to make an adequate amount of insulin needed in order to move the glucose into the cells. However, there are many factors that lead to type two diabetes. They are known to be genetic, high body weight, previously identified impaired fasting glucose levels or impaired glucose tolerance, family history of diabetes, and history of gestational diabetes or delivery of a baby over 9 pounds. Type two diabetes effects about 90% to 95% of the cases of disease in the US (Hinkle & Cheever, 2013). It's
He said, diabetes mellitus is a chronic disease that occurs when the body doesn 't make enough of insulin, or the body doesn 't use insulin properly. Insulin is a key to regulation of blood glucose in our body. In types II diabetes a condition of when insulin insensitivity as a result of insulin resistance that decreases insulin production and eventual pancreatic beta-cell failure enough insulin to meet body needs. Impairment of beta- cell also can lead to problems with insulin production and resistance that can interfere with the process of glucose uptake in by cells and muscle. This condition leads to a decrease in glucose transport into the liver, muscle cells, and fat cells which can lead to a condition called hyperglycemia. Hyperglycemia occurs when there is a high level of blood glucose levels in our blood (Concepts Advisory Panel (2015) p.742).
The other major cause of type 2 diabetes is genetics. The incidence of the disease is high worldwide and varies between populations because of difference in genetic susceptibility and other modifiable risk factors. Many genes have been targeted
Long acting insulin is given by SQ injection once or twice a day depending on patients need. Client education should include proper administration of insulin, as well as what signs to look out for should the dog become insulin resistant, hyperglycemia or hypoglycemic. A diet that is low in fat, high in fiber and complex carbohydrates will allow glucose to be released steadily from the stomach. A diet that is aimed at getting the dog down to a healthy diet and keeping a healthy weight is a must. Food should be given at the same time a day to coincide with insulin peaks after insulin administrations so that glucose absorption is at it’s apex. Client should be advised that close monitoring of insulin therapy is an important part of efficiently regulating the underlying diabetes mellitus.
Being overweight significantly increases the chances of developing a common type of diabetes, type 2 diabetes. In humans, type 2 diabetes is a relative insulin deficiency that causes the cells in the body to develop a resistance to insulin. Insulin, a hormone produced in the pancreatic islet beta cells, helps move sugars into the cell that can later be used as fuel. The deficiency occurs when the functions of the beta cells are damaged. Insulin is unable to be detected because the insulin receptors are damaged from an overload of insulin already present in the pancreas. This causes the insulin to lose its ability to help clear the sugar from the body. A large amount of humans and felines are beginning to develop diabetes mellitus at a fast growing rate due to the body being unable to
Another article related to the gene theory titled Genetic and Environmental Factors Associated with type two Diabetes and Diabetic Vascular Complications conducted in 2012 by Murea, MA, and Freedman. This study focused on exploring secondary data to find what researchers have found about the relationship between genes and diabetes, and environmental factors and diabetes. This study focused more on type two diabetes and how it relates to vascular complications. It concentrates on how finding the relationship between genes and diabetic can help finding treatment option for the disease prevention or delay in the disease progression (Murea & Freedman, 2012). The authors also review and article that reviewed the literature supporting genetic determinants in the
So first is history, so in 1776 Matthew Dobson described a type of diabetes called Mellitus, this was because the blood and urine of the dog tasted sweet and in Greek the word of sweet was mellitus so he named it Mellitus. But when he found it in the urine he thought of it as passing through and in Greek diabetes means to pass through. Then he later called it diabetes mellitus. Then in 1745-1821 Johann Frank defines Insipidus from Mellitus. He found that since Mellitus was its own type he started to notice a different type. One where the dog was constantly drinking and urinating so when he examined a dog he noticed that when they drank a lot as he described it but that is about it considering he
Type 2 diabetes is a complex, multifaceted disease with numerous factors contributing to hyperglycemia. Ultimately it can best be characterized as a disease of insulin resistance and progressive beta cell failure, but numerous factors contribute to each. Non-modifiable risk factors for developing type 2 diabetes include genetics and age. Beta-cell dysfunction and insulin resistance are both inheritable traits. Researches have identified some 50 loci (specific location of a gene) associated with insulin concentration and glucose, while 32 have known associations with type 2 diabetes. Additionally, advancing age is associated with diminished beta cell responsiveness. Modifiable risk factors include weight and environmental factors such
One of the most common lifestyle disorders affecting the global population during recent times is type 2 diabetes. Similarly, certain dog breeds besides dachshunds like the Australian Terriers, Bichon Frises, Cairn Terriers, Fox Terriers, Golden Retrievers, German Shepherds, Keeshonden, Poodles (toy, miniature and standard), Pugs, Samoyeds and Schnauzers (both miniature and standard) are more susceptible to the onset of type 1 diabetes commonly referred to as juvenile diabetes. Nonetheless, on numerous occasions these symptoms go unnoticed by their owners leaving them to suffer in silence. Therefore it is imperative to recognise the early symptoms and help your dachshund’s healthy
Treatments: Diet changes are fundamental. Quality protein, fiber, and complex carbohydrates inhibit the rapid uptake of glucose. Exercise may also help keep glucose levels even. Daily insulin injections are often necessary. They are administered by pushing a needle through the dog’s skin, usually on the shoulder or back.