Lung Cancer Screening
Lung cancer is a malignant transformation and growth of the cells of the lung and the airway tissues. It is usually divided into two main types: Small Cell Lung Cancer (SCLC, 15%) and Non-Small Cell Lung Cancer (NSCLC, 85%) with the latter further subdivided into several subtypes such as Squamous, Large Cell, and Adenocarcinoma among other rare subtypes. Each subtype has its own unique growth and spread pattern with some being more aggressive than others. Lung cancer is staged according to the American Joint Committee by the TNM system, where T stands for the size, N for nodal involvement and M for the presence of distant metastases. The knowledge of the lung cancer main types, subtypes and stage, and the presence of specific molecular and genetic signatures, help the clinician determine the treatment approaches be it surgical, radiation, chemotherapy and the combination of, in addition to the appropriate type of chemotherapy.
Lung cancer has been the most common cancer in the world for several decades. The International Agency for Research on Cancer (IARC) estimates for 2012 was 1.8 million new cases which constituted 12.9% of the total number of new cancers diagnosed worldwide. Fifty eight percent of which occurred in the less developed regions. Lung cancer remains the most common cancer in men worldwide (1.2 million, 16.7% of the total) with the highest estimated age-adjusted incidence rates in Central and Eastern Europe (53.5 per 100,000) and
Lung cancer is the most commonly diagnosed cancer in the world, according to the World Health Organisation. In the UK, it 's the second most-frequently occurring cancer among men (after prostate cancer), accounting for 1 in 7 new cases, and the third most-frequently diagnosed cancer in women (after breast and bowel cancer) accounting for about 1 in 9 new cases. However, numbers have dropped considerably in recent times, by about 16% in the last decade alone.
What are lung cancers? Lung cancers are the abnormal cells which grow in uncontrolled manner in one or both lungs. They do not function as normal lung cells and do not develop into healthy lung tissue. The abnormal cells can grow, form tumours and interfere with the normal functions of the lung (Lungcancer.org, 2015). Lung cancers can be divided into two major types, namely non-small cell lung cancers (NSCLC) and small cell lung cancers (SCLC). NSCLC can be further classified into three main subtypes, namely adenocarcinoma, squamous-cell carcinoma and large-cell carcinoma (Longo & Harrison, 2012). Lung cancers can be diagnosed by chest X-ray, computerised tomography (CT) scan, positron emission tomography-computerised tomography (PET-CT) scan, bronchoscopy and biopsy (Nhs.uk, 2015). Unfortunately, lung cancers are often diagnosed at the later stages. This is due to the unrecognisable symptoms and warning signs at the earlier stages. NSCLC are often diagnosed at stage IV which accounts for 30-40% of cases whereas 60% of SCLC is diagnosed at stage IV. Lung cancer usually originates from the cells lining the bronchi, bronchioles and alveoli. Carcinogens especially tobacco smoke will alter the gene expression of the normal human lung cells, resulting in cell mutation. The proto-oncogenes will be converted to mutated form, oncogenes. Mutation leads to the decreased expression of the tumour suppressor genes. This results in uncontrolled cell proliferation, cell
A doctor can diagnose lung cancer through many tests. The doctor can have x-rays and CAT scans done to see what the inside of the lungs look like. By doing this that doctor is able to see what stage the cancer is in. A doctor may also do a test called a bronchoscope. This test allows the doctor to look inside the bronchial tubes and biopsy the tumor. The doctor then can take a small amount of the cells to study them to determine if the unusual cells are cancerous. If the cells turn out to be cancerous then the patient is in for many months even years of harsh treatment.
Throughout life, many individuals experience difficulties due to growing up in everyday life. While going in depth of the human life, it is discovered that there are many diseases and disorders that affect humans’ everyday functions. A very popular disease that has traumatically affected the human body is cancer. Cancer is a disease that spreads throughout your body in many ways. The purpose of cancer is to attach to a blood cell in your body and cause a plague within itself, causing the body to initially shut down and die. This disease contains many forms and have many causes to it. However its main goal is to destroy the human body.
However, there are stages in the lives of all humans when the body finds itself in a position where it is no longer able to defend itself against ailments and diseases and eventually may even lose the battle. One such disease which claims many lives every year in this manner is Cancer. So far so, there has been no cure for Cancer but some medicines and treatments are now available which can slow down and in some cases can even alter the effects of Cancer, depending on the stage at which the disease is at that moment. For this paper however we would concentrate on Lung Cancer and its effects.
Lung Cancer is a disease which consists of uncontrolled cell growth in lung tissues. Lung cancer consists of two types, Non-small cell lung cancer, and small cell lung cancer. (NSCLC) is the most common type of lung cancer. The bronchi are the large air tubes leading from the trachea to the lungs that convey air to and from the lungs, and where most lung cancers begin. The body normally maintains cell growth only
The leading cause of cancer death for both men and women in the United States and worldwide is lung cancer. Lung cancer is responsible for thirty percent of cancer deaths in the United States. The deaths caused by breast cancer, colon cancer and prostate cancer combined do not add up to the deaths that lung cancer causes. In 2007, 158,683 people, 88,243 men and 70,354 women died from lung cancer in the United States (Eldridge, 2012). Out of the 158,683 people that died from lung cancer in 2007, 135,000 of them died of lung cancer caused by smoking cigarettes. The overall survival rate of those with lung cancer is at about fifteen percent.
Although many people have heard about lung cancer, they don't know that there are two major types of lung cancer. The types of lung cancer are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). NSCLC breaks down into three different types and approximately makes up 85-90% of the cancers that patients are diagnosed with. The first type of NSCLC is adenocarcinoma. This type of cancer is usually found in smokers however it is the most common lung cancer found in nonsmokers. This cancer typically attacks younger adults and targets women. This cancer tends to develop on the outside layers of the lungs and it can be found before it spreads throughout the body. The second type of NSCLC is squamous cell carcinoma. This cancer is linked to smoking and forms in the inner airways of
Cancer, it can affect anyone; it can affect any part of the body but what is it? Cancer results from the abnormality in the body's cells. This occurs when the cells divided and grow. Disruption in the system of the growth and division of a cell results in an uncontrolled division and proliferation of cells that form a mass which leads to cancer. The patient outcome for cancer is different for everyone, but it is also different with each type. In the respiratory department, a major type of cancer we will deal with is lung cancer. Lung cancer, however, has different types and stages, but for this paper, we are going to talk about Stage IIIA non-small cell lung cancer (NSCLC). In the article titled “Stage IIIA Non-Small Cell Lung Cancer” it states
Beneath the lungs, a slender, arch formed muscle called the stomach isolates the mid-section from the guts. When you inhale, the stomach climbs and down, compelling air all through the lungs. Lung tumor begins when cells of the lung get to be anomalous and start to become crazy. As more disease cells create, they can frame into a tumor and spread to different regions of the body. Non-little cell lung growth is a gathering of lung tumors that act likewise, for example, squamous cell carcinoma and adenocarcinoma. Side effects are a hack that won't leave, shortness of breath, weight reduction, or hacking up blood. Medicines incorporate surgery, chemotherapy, and radiation. Lung disease begins when cells of the lung get to be strange and start to become crazy. As more malignancy cells create, they can frame into a tumor and spread to different ranges of the body. Around 80% to 85% of lung growths are non-little cell lung malignancy (NSCLC). There are subtypes of NSCLC, which begin from various sorts of lung cells. Be that as it may, they are assembled together as NSCLC on the grounds that the way to deal with treatment and guess are regularly
Lung cancer is a tumor that affects either one or both of the lungs.A primary cancer begins in the lungs and a secondary cancer begins in another place in the body and makes its way up towards the lungs. Lung cancer is the 5th most common cancer. In Australia 59% of males were diagnosed were as 41% of Australian females were diagnosed.
Lung cancer occurs due to cells in a person’s lungs that multiple at a rapid pace, which form a malignant tumor. These tumors in the lungs take away important necessities such as oxygen, and nutrients; diminishes the ability of the tissue to properly function. One of the most type of common lung cancers is Adenocarcinoma, which make up to forty percent of these cases. Smoking is the primary reason for Americans to be diagnosed with lung cancer, with a cigarette containing more than 4,000 chemicals that have permanent damage to the lungs causing long term effects (Conrad 2016).
One of the leading and most avoidable risk factors of lung cancer is smoking. In both males and females smoking is linked to a higher incidence of lung cancer at an increase of 23% and 13% respectively. Smoking not only increases the likelihood of lung cancer, but has shown a correlation in higher risk of other cancers such as oral, laryngeal, pharyngeal, esophageal, pancreatic, ovarian, and multiple more. As a whole,
Cancer can be one of the hardest battles that one must face, whether that battle is lost or won, it changes the lives of everyone involved. Lung cancer is one of the most diagnosed cancers and it affects the lining of the lungs and the ability to breathe. Lung cancer is the number one killer of men and women than any other cancer worldwide. This cancer is mostly found in smokers and this is why professionals are targeting this population for testing for diagnosing early and possibly saving a life (www.ncb.nlm.nih.gov). Lung cancer refers to the malignancies that originate in the airways or pulmonary parenchyma.
|Specific Purpose: |To inform readers on the causes, effects and treatments of lung cancer. |