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Mitosis and Meiosis

Satisfactory Essays

2/24/2013

Cell division
• The human body is made up of trillions of cells…

Mitosis and Meiosis

• …But started with one

Understanding Cell Division
• What instructions are necessary for inheritance? • How are those instructions duplicated for distribution into daughter cells? • By what mechanisms are instructions parceled out to daughter cells?

Reproduction
• Parental cells produce a new generation of cells or multicelled individuals like themselves • Parents must provide daughter cells with hereditary instructions, encoded in DNA, and enough metabolic machinery to start up their own operation

The roles of mitosis

Chromosome
• A DNA molecule & attached proteins • Duplicated in preparation for mitosis

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Meiosis is the process that produces haploid gametes from diploid genomes.

Maintaining Chromosome Number In Mitosis

Meiosis must reduce chromosome number

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Chromosome Number
• Sum total of chromosomes in a cell • Germ cells are diploid (2n) • Gametes are haploid (n) • Meiosis halves chromosome number • When two gametes fuse, they form a new, diploid cell (zygote)

Human Karyotype
Diploid organisms have two copies of each chromosome, one of which they get from their father, the other which they get from their mother. These equivalent chromosomes are called homologous chromosomes.

Life Cycles of Diploid Organisms

Meiosis: Two Divisions
• Two consecutive nuclear divisions
– Meiosis I – Meiosis II

• DNA is not duplicated between divisions • Four haploid nuclei form

Meiosis has two divisions

Do not confuse “homologous” with “sister” chromosomes

Sisters Sisters Homologs

Sisters

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Meiosis – Stages

Prophase I
• Each duplicated chromosome pairs with homologue • Homologues swap segments (crossing over) • Each chromosome becomes attached to spindle

Metaphase I
• Homologous pairs line up in the middle of the cell • The spindle is fully formed

Anaphase I
• Homologous chromosomes segregate • The sister chromatids remain attached

Telophase I
• The homologous chromosomes arrive at opposite poles • Usually followed by cytoplasmic division

Results of Meiosis I

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