Muscular Dystrophy : The Different Types And The Problems Associated With Dystrophy

Muscular dystrophy is a degenerating disease, in which the skeletal muscles degenerate, lose their strength, and cause increasing disability and deformity. Muscles attached to the bones through tendons are responsible for movement in the human body, however, in muscular dystrophy the muscles become progressively weak. As the muscle fibers

Listener Relevance: Duchenne Muscular Dystrophy (DMD), is more common than people think and chances are sooner or later you will know of or see somebody affected by this disease.

Duchenne muscular dystrophy (DMD) is defined as a chronic form of dystrophy that is caused by a mutated gene. This essay critically discusses Duchenne muscular dystrophy as a whole, including all the symptoms, causes as well as treatment.

Overall, the lack of dystrophin in DMD individuals causes many problems in different aspects of metabolism. It has a massive effect on muscles, affecting the shoulders, hips, calves, thighs, pelvic area first. Like other muscular dystrophies, DMD affects the voluntary muscles first and then will progress into other muscles. Limb-girdle muscular dystrophy is another type out of the many that affect voluntary muscles. Specifically, it targets the hips and shoulders.

Duchenne Muscular Dystrophy (also referred to as DMD) is a type of muscular dystrophy that weakens the muscles that we need to support our body, body weight, to stand, and to move around. It also can cause you to have scoliosis. Some of the main causes for DMD are genetic disorders, mutations, and DMD has to be passed down throughout everyone in that family for generations. The symptoms you can have if you have DMD are weak muscles, lack of strength, and difficulty walking. DMD is a negative mutation because it affects your muscles horribly bad that you can get a disability of walking and even moving. You need to tell your doctor immediately if you experience any symptoms. If you don't tell your doctor, you may find yourself in a very difficult situation where you can't get up or can't get something you need. When you do talk to your doctor, you will have an advantage of getting the help you need.

muscular dystrophy has many forms and therefore symptoms can vary between the variations. Overall symptoms include the weakening of skeletal muscles and the defect and death muscle tissues. Duchenne muscular dystrophy is the most common and affects young boys such as Eddie.

Duchenne Muscular Dystrophy is a sex-linked disease, which is inherited in a recessive fashion (National Human Genome Research Institute, 2013). Over thirty similar genetic disorders exist (Duchenne Foundation Australia, 2015). All types of muscular dystrophy are considered to be a rare disorder (Duchenne Foundation Australia, 2015). Duchenne Muscular Dystrophy is most common in children and causes muscle weakness and wasting, which commonly begins in the lower limbs (Duchenne Foundation Australia, 2015; National Human Genome Research Institute, 2013). The disease itself is caused by changes to the DMD gene, which is responsible for providing instructions regarding the creation of the dystrophin protein in one’s muscles (Duchenne Foundation Australia, 2015). This protein is responsible for protecting muscles from damage, and without it the cells of a person’s muscles deteriorate and symptoms of Duchenne Muscular Dystrophy are exhibited (Duchenne Foundation Australia, 2015). The disease results from changes in the DMD gene, or other genetic changes in a child (Duchenne Foundation Australia, 2015).

Nowak KJ, & Davies KE. (2004). Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment. EMBO Reports, 5(9), 872-876. doi:10.1038/sj.embor.7400221

Duchenne muscular dystrophy, classified as a genetic disorder, is marked by progressive muscle degeneration and weakness. It is only one of the nine forms of muscular dystrophy; however, around half of the people diagnosed with muscular dystrophy have Duchenne muscular dystrophy.

Even though the annual telethon is over, muscular dystrophy—all nine forms—still exists. MD presents with a combination of muscle weakness and muscle wasting.

One major problem associated with Duchenne Muscular Dystrophy (DMD) is the prevalence of fibrosis that occurs in the skeletal muscles, heart, and lungs of these patients. In the heart and lungs, fibrosis inhibits the body’s ability to perform cardiopulmonary or respiratory function, respectively. These conditions typically result in death if no emergency medical attention is given. Fibrosis can also present as contractures in the skeletal muscle fibers, which will usually result in the loss of skeletal muscular function and the need for surgery.

According to M.D. Sarnat Harvey, Dystrophy means abnormal growth, and muscular dystrophy is abnormal growth of muscles causing weakness and death of muscle. Over time, the patients lose the freedom of walking, running, playing, talking, even breathing abilities. There is no cure for muscular dystrophy.

Duchenne Muscular Dystrophy or DMD for short is a genetic disease that affects the skeletal muscles causing muscle degeneration and muscle wasting. Duchenne Muscular Dystrophy is an X-linked recessive chromosomal disease, which is caused by mutations in the DMD Gene (Regenerative Medicine). This Disease affects 1 in 3600 boys (Regenerative Medicine). A male born with this disease experiences respiratory dysfunction, trouble ambulation, cognitive impairment, some even experience premature death. Unfortunately, there is no cure for DMD, but there are research studies in the works for different therapies to help reverse this gene mutation and to elevate symptoms associate with this disease.

DMD occurs at a frequency of one per 3,500 live births (MD). Muscular Dystrophy (MD) is the name for a group of disorders where muscle size and strength decrease over time. (DMD) is a genetic disease that begins when the occupant is three. Most (MD) involve the muscle cells dying and then being replaced by fat and connective tissue. These muscles cells being replace by fat causes the muscles to weaken over time which makes (DMD) a degenerative disease. The end results is the patient loses all control over his or her muscles, is no longer able to walk, and eventually dies of respiratory failure.

Muscular dystrophy develops weaker and less muscular mass in a category of diseases. Our healthy muscles need more formulation of proteins. Therefore, this only transpires when genes are imperfect. There are nine major types of muscular dystrophy, which include duchenne, becker, congenital, limb-girdle, facioscapulohumeral, emery-dreifuss, distal, myotonic, and oculopharyngeal. Distinguish decay and reconstruction of the muscle fibers, making the skeletal muscle and muscle proteins weaker. Additionally, killing muscle tissues and cells. Due to all the different types of categories of muscular dystrophy most symptoms start at different ages. The condition does not discriminate it affects males, females, and all races. It does occur more with families who have a history with muscular dystrophy.