Nucleophile And Aldol

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The aldol addition reaction, may involve the nucleophilic addition of a ketone enolate to an aldehyde. Once created, the aldol product loses a molecule of water to form an a, B-unsaturated carbonyl compound which is called aldol condensation. A variety of nucleophiles may be in the aldol reaction, involving the enols, enolates, and enol ethers of ketones, aldehydes, and many carbonyl compounds. The electrophilic partner is more than likely an aldehyde or ketone. When nucleophile and electrophile are different, the reaction is called a crossed aldol reaction; on the contrary, the reaction is called an aldol dimerization when the nucleophile and electrophile are the same.
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