Osteoporosis
Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture.[1] Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal
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While osteoporosis occurs in people from all ethnic groups, European or Asian ancestry predisposes for osteoporosis.[4] Those with a family history of fracture or osteoporosis are at an increased risk; the heritability of the fracture as well as low bone mineral density are relatively high, ranging from 25 to 80 percent. There are at least 30 genes associated with the development of osteoporosis.[5] Those who have already had a fracture are at least twice as likely to have another fracture compared to someone of the same age and sex.[6]
[edit] Potentially modifiable
• Excess alcohol - small amounts of alcohol do not increase osteoporosis risk and may even be beneficial, but chronic heavy drinking (alcohol intake greater than 2 units/day),[7] especially at a younger age, increases risk significantly.[8] • Vitamin D deficiency[9] - low circulating Vitamin D is common among the elderly worldwide.[10] Mild vitamin D insufficiency is associated with increased Parathyroid Hormone (PTH) production. [10] PTH increases bone reabsorption, leading to bone loss. A positive association exists between serum 1,25-dihydroxycholecalciferol levels and bone mineral density, while PTH is negatively associated with bone mineral density.[10] • Tobacco smoking - tobacco smoking inhibits the activity of osteoblasts, and is an independent risk factor for osteoporosis.[7][11] Smoking also results in increased breakdown of exogenous estrogen, lower body weight
Osteoporosis is a medical condition in which the bones become brittle from the loss of tissue, generally as a result of specific changes. Risk factors that take part in the disease are things such as unchangeable risks like sex, age, race, family history and the size of the individual. Other risk factors include hormone levels and medication as well as dietary factors and life choices. Life choices that play a role are sedentary lifestyle these are people who spend a lot of time sitting have a higher risk of osteoporosis than do their more-active counterparts, weight-bearing exercise is beneficial for your bones to ensure the bone remolding cycle ensures them to grow strong (MayoClinic, 2013). Common symptoms that one should take into
(Kling, J. M., Clarke, B. L., & Sandhu, N. P., 2014, p. 567). Osteoporosis risk factors
There are a plethora of health issues that contribute to bone loss, such as nutrition (low calcium consumption) and rarely engaging in exercise, people who have an unhealthy lifestyle such as smoking or extreme alcohol usage are also at risk. “Bone loss in adolescence and early adulthood can be a result of a failure to attain peak bone mineral density, and accelerated bone loss may be particularly noted around menopause and in later years” (Lin, 2014, para. 1). Though the exact cause is unknown, additional sources may include latent health disorders such as thyroid problems.
The people most likely to develop osteoporosis are older White or Asian women, and often have a small body size. This disease also runs in families. If a relative develops osteoporosis, or breaks a bone, it is probable that you will too. If you do develop the disease, several treatment options are available to you. First and foremost, diagnosis is often required before any treatment can be administered.
Bone density is made up by about 20% of your lifestyle and 80% is from your heredity. Osteoporosis is a bone disease that decreases bone density. Characteristics of this disease include: decreased height, increased curve of the spine, and falling due to fractures. Since osteoporosis affects bones only, it does not affect any other body systems except for the skeletal system. The cause of osteoporosis occurs as people become older. Their bone mass is lost faster than it is created, unlike when people are younger their body makes bone faster than it breaks it down. Chemically osteoporosis decreases calcium intake, lowers vitamin D level, increased bone resorption, and hyperparathyroidism can result.
Some ethnicities are more prone to osteoporosis than others. For example, osteoporosis is more common in Caucasian and Asian women. Osteoporosis affects approximately 1.4 million Canadians, mainly postmenopausal women and the elderly [8]. In Canada, almost 30,000 hip fractures occur each year (8). By the year 2030, the number of hip fractures is expected to quadruple (10,11). (Where is ref. No 9?)
“Most [women] reach their peak bone mass by their early 20s…and as [they] age, bone mass is lost faster than it's created” (Mayo Clinic, 2014). The more bone mass created during youth the less likely it is for osteoporosis to develop, so adequate nutrition is important. According to NIH (2014), “the daily recommendation for calcium from ages 9-18 is 1300mg and 1000mg/day thereafter. For vitamin d, it is 600IU/day after age 1” (NIH, 2014). Along with nutritional deficiencies, women who smoke, drink, and don’t exercise regularly are at higher risk for osteoporosis. Some non-behavioral risk factors include “having a family history of osteoporosis, being female, having a small frame, certain disorders such as rheumatoid arthritis, type 1 diabetes, and anorexia nervosa; taking some medications for example glucocorticoids, gonadotropin releasing hormone, or antacids with aluminum, and menopause” (McGowan, 2012). Asian and white women are also more predisposed to having this
I have enjoyed reading your post, Sarah. I found your comments on osteoporosis informative and educational. As you have stated, osteoporosis can lead to bone fracture. This condition is common among older women. However, it can affect both genders as people age. Osteoporosis may also be linked other diseases and cancers. Osteoporosis may be silent. The individual may not know that he or she have it until they experience a fracture. Prevention is the best way to reduce the risk of developing Osteoporosis. Calcium is very important to healthy bones. Vitamin d intake is essential for calcium absorption. Therefore, adequate calcium and vitamin d intake are essential for healthy bones. Exercise is also important for bone health. It is important
Osteoporosis is a disease of the bone that makes a person’s bones weak and more likely to break. It is often known as a silent disease because you can’t feel your bones getting weaker. About 10 million Americans have osteoporosis and another 44 million have low bone density, placing them at increased risk. Studies suggest that approximately one in two women and up to one in four men age 50 and older will break a bone due to osteoporosis. A woman’s risk of fracture is equal o her combined risk of breast, uterine, and ovarian cancer. A man is more likely to break a bone due to osteoporosis than he is to get prostate cancer. If you’re age 50 or older and have broken a
Definition. Osteoporosis is a progressive bone disease that is characterized by low bone mass along with continuous loss of bone tissue with increased fracture risk. The pathology is multi-factorial and there are several modifiable and non-modifiabale factors that contribute to the development of this disease. According to the World Health Organization, osteoporosis is defined as a systemic skeletal disease illustrated by a decrease in bone mass and bone tissue, causing a decrease in bone and a subsequent increase in fracture risk (1).
Osteoporosis is the most common disease of the skeletal system that points out a decreased bone mass and as a result produces an augmented risk of fractures which identify the main cause of clinical disease. Often, it is called the silent disease because bone loss occurs silently, gradually and without symptoms until the first fracture originates. Worldwide, osteoporosis is seen as a global health problem affecting more than 200 million people (International Osteoporosis Foundation, 2014). Specifically, 1 in 3 women over age 50 suffer bone fractures in contrast to 1 in 5 men (International Osteoporosis Foundation, 2014). Of course, the prevalence of broad scope of osteoporosis is higher in women who represent 80%. On the
Osteoporosis literally means ‘porous bone’, it is a disease that weakens bones and increases the risk of sudden fractures. Quite unfair but true that women are at a greater risk for osteoporosis than men. The statistics for osteoporosis from National Institute of Arthritis and Musculoskeletal and Skin Disease shows that in 44 million of people 68 percent of women are at a risk of osteoporosis. Women over 50 years of age have more likely to have fracture related osteoporosis in their lifetime. In all cases of hip osteoporosis 75 percent of them are women. This disease may have its root from adolescence and even childhood that is the period of bone building in your body.
Age, race and gender increase risk factors however so are lack of exercise, diet low calcium rich foods, smoking and consumption of alcohol (Office of women’s health[OWH], 2018). Osteoporosis may not be completely preventable, yet women should be aware of the risk factors that they can modify to decrease the risk. Osteoporosis is a disease that affects the bones making them thinner or more porous (OWH,
Osteoporosis causes weakness of the bones and brittle in some cases stress such as turning on the bed or falling down can cause a fracture. According to Mayo clinic, Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Normal bones’ tissue is constantly being replaced by breaking down the old bone tissue and old bone is replaced with new bone tissue. Osteoporosis occurs when the old bone is not being replaced by new bone tissue. There are not specific races in which an individual is more prominent but men and women after menopause are more prominent to contract this disease. Aging, diet low in calcium and vitamin D, smoking, drugs and certain for example, chemotherapy medication which causes bone loss, are
Osteoporosis is the most common progressive bone disease that decreases bone density. Osteoporosis is characterized by an increased risk for bone fracture and this presents in the form of brittle and fragile bones (Bethel & Diamond, 2016). The bone loss occurs because of increase bone reabsorption which leads to decreased bone mass and deterioration (Bethel & Diamond, 2016). In addition, impaired bone function can also lead to osteoporosis. The diagnosis of osteoporosis often happens after the injury has occurred.