Pro Inflammation

Decent Essays

Inflammation is a normal immune reaction in response to tissue injury or invading exogenous molecules/ pathogens and can be either localized or systemic. The aim of acute inflammation is restoring the tissue homeostatic imbalance by promoting tissue repair and eliminating the causative stimuli through a complex but highly regulated cascade of events (Medzhitov 2008). Under physiological conditions, successful acute inflammation is followed by a resolution phase during which pro-inflammatory processes are suppressed and physiological homeostasis is achieved. However, an ongoing inflammatory event or an impaired resolution phase characterized by continuous pro-inflammatory processes results in chronic inflammation (Maskrey et al. 2011; Fullerton

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