Research Questions On Rheumatoid Arthritis

"Rheumatoid joint inflammation is an interminable infection set apart by irritation of the joints, frequently influencing the hand joints and both sides of the body in the meantime" (Royal Australian College of General Practitioners, 2009).

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the

Rhematoid Arthritis – Is an autoimmune disease which can cause chronic inflammation of body`s organs, joints, and the surrounding tissue of the joints. It can

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Rheumatoid Arthritis has been subject of numerous studies and researches in the look for a better understanding of how it effects the individuals diagnosed with it. There is a higher incident of females diagnosed with RA than male as well as a relationship with genetic and environmental factors involved. Around one percent of the world population is affected by RA; therefore, diverse studies have been performed to understand how the lives of the diagnosed patients can be impacted by the disease. For example, how RA affects the mobility, safety and activities of daily living in general as well as the development of interventions to better approach RA. On

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease. The disease happens when the immune system mistakenly attacks a healthy tissue as if it was a foreign invader, such as a virus or bacteria. If left untreated it can lead to permanent joint damage, decrease in quality of life, and total disability. It affects over a million people in the U.S. alone. Rheumatoid arthritis symptoms include persistent joint inflammation which causes joint pain, stiffness, and swelling. Fatigue and stiffness are usually early symptoms. Joint pain can be an early symptom in a variety of diseases. Symptoms of rheumatoid arthritis often develop slowly over a period of weeks or longer, but this is not always the case, it can have an acute

Rheumatoid arthritis is a chronic inflammatory disease affecting the joints, most often in the hands and feet. It results in swelling, stiffness, pain, and sometimes joint, bone, and cartilage destruction. Rheumatoid arthritis usually affects joints on both sides of the body equally, meaning if a joint on one side is affected, the same joint on the opposite side is affected as well. Rheumatoid arthritis belongs to a group of diseases called autoimmune disorders that affects joints. In rheumatoid arthritis, the immune system produces antibodies that attack the soft tissues lining of the joints. Eventually the cartilage, bone, and ligaments of the joint deteriorate, causing deformity, instability, and scarring within the joint

Rheumatoid Arthritis is a systemic autoimmune disorder. There are more than 100 different types of Arthritis, yet it is estimated that it affects approximately 1% of the population in the Western World. The disease is generally diagnosed in middle aged adults and the elderly. In rarer cases, children can also develop the disease and it is called Juvenile Rheumatoid Arthritis. Women are three times more likely to have rheumatoid arthritis than men. (Stevens) Many people living with Rheumatoid Arthritis appear to be healthy individuals, but suffer internally. Today, I will discuss what rheumatoid arthritis is, how it is diagnosed, and how it affects the body.

Rheumatoid arthritis (RA) is a systematic inflammatory disease characterized by synovitis (constant inflammation of the synovial membranes) and autoantibodies. The disease that affects 0.5-1.0% of all adults in industrialized countries, mostly women and elderly people (Scott et al, 2010). In the United States, more than 1.5 million people suffer from rheumatoid arthritis, making it one of the most common auto-immune disease (Carmona et al. 2010). According to the Arthritis Foundation, individuals who suffer from arthritis have to deal with joint pain, morning stiffness, fatigue, loss of appetite, depressive symptoms, and low-grade fever which can last a few days to weeks. Individuals with this disease tend to have a low-quality of life and difficulties with day-to-day activities.

Thank you Prianca for taking the time to share about the cytokines and their interaction in the inflammatory process of the Rheumatoid Arthritis. Indeed, the epidemiology incidence of Rheumatoid arthritis (RA) is increasing every minute. Like you well explain above in your post, we have more than 1.3 million of people in the US affected with RA (Ruderman & Tambar, 2013) and 1 percent of the worldwide population is affected with RA (Lubberts & Berg, 2003). It seems like this epidemic is going to continue. 75 percent of that 1.3 million are women, and statistically, 1 of 3 women may get rheumatoid arthritis in their life. Rheumatoid arthritis can affect anybody at any age, but in most of the cases, the disease begins in the 40’s and 60’s (Ruderman & Tambar, 2013).

Rheumatoid arthritis is a chronic, systemic autoimmune disease characterized by inflammation of connective tissue in the diarthrodial (synovial) joints, typically with periods of remission and exacerbation (Lewis, Dirksen, Heitkemper, Bucher, & Camera, 2011). The etiology of rheumatoid arthritis is unknown. Autoimmunity and genetic factors are believed to be important in the development of RA. Genetic predisposition appears to be important in the development of RA (Lewis et al., 2011). The strongest evidence for a familial influence is the increased occurrence of a human leukocyte antigen (HLA) (Lewis et al., 2011). Smoking can increase the risk of RA for a person who has a genetic predisposition. Autoimmunity theory suggests that changes

Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.

Rheumatoid Arthritis (RA) is a common autoimmune disease. The chronic inflammation they induced lead to severe joint swelling and damage2. It is more likely to strike on aged people and females3. In Australia, 400,000 people are suffering from it with different extent3-4. The mechanisms of the disease are well-studied. The synovium is the primary target of the immune system for RA patients. With white blood cells migrated in, the synovium membrane becomes thick and inflamed, which leads to undesired tissue growth3. Various chemical substances are released from the inflamed site and starts affecting surrounding tissues, such as cartilages and ligaments. In severe cases, they might even result in whole-body disorder2-4.

In the United States, arthritis has become the second most common disorder, in the past years. Moreover, the condition affects more than 34 million Caucasians, 4.6 million African-Americans and nearly 3.1 million Hispanics with women being the most affected (Helmick, 2008). 28.3% of people suffering from arthritis are women whereas 18.2% are men (Helmick, 2008). By the year 2030, it is predicted that the number of patients with arthritis will double if prevalence rates remain the same. Apart from being cost-intensive, Osteoarthritis (OA) affects nearly twenty seven million Americans, which effectively limits their work (Reid, Shengelia & Parker, 2012). The statistics show that Caucasians are the most affected and the Hispanics to be the less affected from Caucasians, Hispanics, and African Americans. It also shows how women also have greater possibilities of getting arthritis than man ever did.