Role of Gluthathione Pathway in Discovering Anticancer Compound

Cancer, by definition, is a cell or group of cells that proliferates uncontrolled. The change in genetic material causes the cell to act strangely, an example being rapid proliferation. Groups of cancer are called tumors, which can spread to different parts of the body. In cancerous cells, the genome has been edited in an unhealthy way by carcinogens. Carcinogens are cancer-causing materials or

According to statistics published by the American Cancer Society, there will be an estimated 1.5 million new cancer cases diagnosed each year over the next decade. What factors contribute to the yearly incidence

From surgery to radium exposure to such extremes as radiation therapy, as doctors’ knowledge of the varying types of cancer, and the expansion of medical research regarding cancer has changed, so has the preferred method of treatment. Doctors and researchers dedicated to studying cancer have led to a greater understanding of cancer development; consequently the development of treatments and cures that are more effective, less harmful, have fewer side effects, and in some cases serve to prevent the spread of cancer.

Cancer is a term used for diseases in which irregular cells divide without any control and have the capability to penetrate and infect normal body tissue through the blood and lymph system. Cancer is the second leading cause of mortality in the United States, exceeded barely by heart disease. According to the CDC Cancer Statistics and Data, there were more than 1.45 million people diagnosed with various kind of cancer between 1999 and 2007 and out of those more than 562,000 people died due to cancer (cdc.gov, 2012). Currently there are more than 200 different types of cancer that have been discovered. Cancer could be

In the United States alone, there was an estimated 1,685,210 new cases of cancer and an estimated of 595,690 people will die from the disease in 2016 ("Cancer Statistics”). Cancer is a very common aliment that affects men, women, children, and all races and ethnicities. There are many different types of cancers, and cancer research has been a focal point for many scientists. There are various treatments that a cancer patient to undergo. Surgery, chemotherapy, radiation therapy, and immune therapy are among the most common ones. Each treatment works differently, and has different positive and negative side effects.

A malignant neoplasm is the medical terminology for Cancer, there are many types of cancers, however, they all are comprised of unregulated cells that show growth or a change. These cells that are cancerous, grow at a hasty rate and will take over other parts of the body, whether being another organ or tissue surrounding the compromised body part. This can also involve the lymph nodes, as well as travel through the bloodstream. There are many influences that contribute to the chance of developing cancers, some of these factors include tobacco use, being overweight and not physically active, exposures to chemicals, and poor nutrition and dietary selections, ones with mutagens in foods, continued or excessive consumption of alcohol, eating foods which are high in fats, and red meat just to name of few. Other types of cancer may be factored by family history, known as a genetic risk, as well as certain viruses that

Globally, cancer is one of the leading causes of death (Fitzmaurice et al., 2015; WHO, 2012). It is continue to consider as a pandemic disease, take into account it's increasingly prevalence rate worldwide (Jacox, Daniel & Payne, 1994; American Cancer Society, 2015).

Cancer is the most prevalent public health challenge worldwide, hence becoming the second leading cause of death in 2013 (cite!). The illness develops when abnormal body cells survive and new cells grow, which are to replace old and damaged ones (cite!). Healthcare professionals associate cancer prevalence with risk factors such as smoking and obesity (cite pg#87) and according to research studies, one in every three individuals will develop cancer (cite!). Such statistics correspond to the occurrence of cancer in the United States, with prostate cancer affecting 105.3 per 100,000 people nationwide (cite!). For the past decade, cancer drugs have increased from $10,000 in the 1990s to $100,000 by 2012; therefore, many patients may die because

Cancer is a disease that develops from uncontrolled cell growth. These cells are capable of invading neighboring or distant parts of the body through the circulatory system. A [benign] tumor, which is sometimes confused with cancer develops from uncontrolled cell growth, but does not spread to other parts of the body. Cancer is a large family of diseases and each one is distinct from the other. Colon cancer, one of the most common cancers in America, usually develops in gladular cells in the large intestine.

Cancer stands to be the most prominent causes of death in economically developed countries and the second leading cause of death in developing countries. Cancer often comes from the materialization of a tumor because of a gene mutation. When a gene mutates it could allow rapid growth, fail to stop uncontrolled cell growth, or make mistakes when repairing DNA errors. If any of these mutations occur, it will cause the cell to grow and divide more rapidly. This creates many new cells that all have a constant mutation. Tumors form in the body when cells are produced uncontrollably, meaning that new cells are produced when they are not desired, and then they cluster together to create a tumor. Tumors can either be benign, which means that it is non-cancerous, or it can be malignant, which means that it is cancerous. If cells break off from a malignant tumor, they will enter the bloodstream, and spread throughout the body.

Cancer is a term that classifies the compilation of diseases that may occur anywhere in the body due to rapid formation of abnormal cell growth. Normal cells develop into abnormal cells when there is damage to the DNA. Hyperactive reproduction of abnormal cells or cancer cells will develop into lumps that may either be benign or malignant. Benign masses are non-cancerous and usually remain in the same area from which they formed in the body. Malignant masses on the other hand are cancerous and tend to spread and multiply to more than one area in the body.

WHAT IS CANCER The word cancer actually encompasses many diseases, not one. In fact, there are more than 100 types of diseases known collectively as cancer. What they all have in common is the uncontrollable growth and division of cells, tiny units that make up all living things. Normal body cells cultivate and divide over a period of time until they eventually die.

Cancer, the uncontrolled, rapid and pathological proliferation of abnormal cells is the growing public problem whose estimated worldwide new incidence is about 6 million cases per year. It is one of the most dreaded diseases of the 20th century and spreading further with continuous and increasing incidence in 21st century. This is the second leading cause of human death after cardiovascular diseases in developing as well as advanced countries. Although there are many therapeutic strategies including chemotherapy and radiotherapy, high systemic toxicity and drug resistance limit the successful outcomes in most cases

The characterization of abnormal cell proliferation and the cells ability to spread throughout the body in an uncontrollable manner is known as the phenomenon of cancer. Cancer is a collection of many diseases that can occur throughout any part of the body. These disease can fall under any of the following categories of cancer: carcinoma, sarcoma, lymphomas, and leukemia’s.

Cancer is a serious and ever growing disease throughout the United States and across the globe. According to data from the National Cancer Institute (2016), about 39.6% of men and women will receive a cancer diagnosis within their lifetime. Due to advancements in screening and treatment, more people are now living with cancer longer than ever before. In 2014, there were close to 14.5 million people living with a cancer diagnosis and this number is going to rise nearly 5 million over the following 10 years (NCI, 2016). The 5-year survival rate for all cancers is also quite high at 68%. Despite the hopeful fact that survival rates are increasing, the incidence rate is also growing, meaning more people are being diagnosed with cancer (Von Roenn et al., 2013).