Executive summary
There have been concerns among the safety of long acting Beta agonist referred to as LABA therapy. This is after the long acting inhaled beta has been used in the treating of asthma since the year 1990. In order to get information about the effect of long acting beta agonists, information was extracted from authoritative journals that were written after the FDA’s recommendation. These journals were written in order to address the concerns that came after Asthma patients who had used long term beta agonists when it came to the treatment of asthma (Lötvall, 2012: 32). This paper will argue about the safe use of long acting beta agonist in asthma patients and the recommendations of its use.
Research methodology
The material for this research was gotten from various journals such as US National library of medicine as well as other databases such as Medical research journal. The information from these journals is credible as the journals are peer reviewed and scholarly. Since the introduction of the extensive acting beta agonists, there has been an improvement for many people that live with asthma (Lötvall, 2012 39). The benefit to these people has been dramatic and consequently there have been fewer asthma symptoms when it comes to rest with exercises, there are fewer night time awakenings and less asthma burn ups. Source of concern
The source of concern when it comes to long acting beta agonists is the fact that it sometimes causes severe asthma
Albuterol has affinity to β 2 receptors and binds to them, causing a relaxation effect. β2 receptors are members of the adrenergic family of receptors and therefore its effects are caused by an interaction with G proteins. β
History of Present Illness: Ms. Dahlberg is a very pleasant 69-year-old woman who suffers from poorly controlled asthma. She has a recent exacerbation requiring hospitalization at Anna Jaques Hospital in June. Since discharge, she states that she has done well. She has stable dyspnea on exertion. She does feel that perhaps it might be slightly worse given the heat and humidity. She is not complaining of any cough. She is compliant with her bronchodilator regimen.
The author of the article is Walsh, Timothy who has an MD a graduate of Princeton University and of Harvard Medical School. The article was originally published at an organizational site called the American Association for the Advancement of Science, in 1998. The web site was last update on February 24, 2016. The information on the article seems accurate and reliable although sometimes on organizational sites the information is biased toward the
A course assignment presented to the College of Graduate Health Studies in partial fulfillment of the requirements for the Doctor of Health Science Degree A. T. Still University
Finally, one article was found by conducting a search of the identified article’s reference section. This article was searched by title on the Cochrane database and was found useful to the clinical
Please list the references and clinical resources that you use in your review of this document. These references should support any clinical or extensive revisions or additions that you make. Aside from known common best practices, references are required. We reserve the right to request additional references. References and resources used:
The goal of treatment is to reduce occurrence of symptoms, prevent exacerbations, maintain normal or near normal pulmonary function, and for the patients to live a normal life as much as possible. According to the NAEPP, asthma control is the degree to which the manifestations of asthma are minimized by therapeutic intervention and the goals of therapy ae met (Woo & Wynne, 2012, p. 996). The Expert Panel Report 3: guidelines recommend a step wise approach to pharmacological management of asthma. It can be a step down approach, where treatment can begin with a higher level of therapy or step up approach, where the initial treatment starts low, depending on the severity of the patient’s condition during the initial visit. The medications are divided into 2 categories: 1) quick-relief medications to
The study was a systematic review of scientific papers selected by a search of the SciELO, Cochrane, MEDLINE, and LILACS-BIREME databases. Among the 2169 articles found, 12 studies proved relevant to the issue and presented an evidence strength rating of B. No publications rated evidence strength A. Seven of the studies analyzed were prospective cohorts and 5 were cross-sectional studies.
The effect of asthma can range from mild, irregular symptoms causing minor problems for an individual to severe and sudden asthma attacks. The extent of what causes asthma is not well known or fully understood but some common triggers include, cold temperatures, dust mites, cockroaches, pollen, sickness, mould and animal hair. When triggered, the airways in the lungs become inflamed and constricted causing shortness of breath, chest pain and wheezing [R]. Currently, there is no cure for asthma however symptoms can be managed with medication and improved living standards [R]. Asthma symptoms are commonly controlled with the use of inhalers, either preventers (taken to desensitizes airways to triggers) or relievers (provides instant relief by relaxing the muscles) [16].
In the article Asthma: Versatile Treatment for A Versatile Disease by Kevin R. Murphy, he discusses the many factors that affect asthma and how inhaled corticosteroid (ICS) are used for all different levels of asthma. Kevin R. Murphy brings up factors such as air pollution and smoking that contribute to the variable nature of asthma which affect people with asthma every day. I will be evaluating the points that Kevin R. Murphy made about the factors that affect asthma and how versatile treatment is for asthma.
Research in the medical field is an ongoing pursuit that is expanding our understanding of the human body and those things that plague it. Scientific inquiry should hold no personal gain, but rather provide safe and empirical data on which to base the decisions
Parameters of this review include literature researched has not considered remote geographical areas such as developing countries, only western based, English research has been evaluated. This is a nurse focused review so literature involves nursing input. Search engines used were google scholar, science direct, The BMJ, PubMed and ProQuest. Literature used does not date past 2004, except for one from 1999 which is proving a
Scientists have for the first time identified the root cause of asthma and the importance CaSR’s in the treatment. As a result they have been able to produce a treatment that counteracts the many side effects associated with asthma. Although researchers have shown calcilytic are able to block the receptors, the longevity of the effect is still unknown. It’s still unclear how long the treatment will stop the lungs producing large numbers of receptors.
Table 1 displayed basic data on demographics such as gender, age, asthma history etc. Figure 1 shows a chart breaking down screening and randomization process of how many patients actually finished the twelve-month treatment. Figure 2 shows results for the four different asthma factors that can affect the enhancement of CB in AIT, and compare to other blood samples taken at month 6,7, and 12 subsequently. Table 2 displays the standard deviation scores for medicine and within six months the combination of both AIT and used together had the smaller deviation and that the scores were very close together compared to the other treatment groups. Figure 3 shows that CB enhances AIT in patients based on immunoglobulin. Table 3 shows that the standard deviation between all four treatment