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Salmonell A Major Cause Of Foodborne Illness Worldwide

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Salmonella enterica sub enterica are a major cause of foodborne illness worldwide. Contaminated food products such as pork, meat, milk, fruits, vegetables, egg and egg products are the common vehicles of Salmonella infections (Hur et al., 2012). It is estimated that gastric illness caused by Salmonella spp. accounts for 93.8 million cases and 155,000 deaths worldwide each year (Majowicz et al., 2010). This statistic clearly indicate that Salmonella infections are public health and financial global burden for both industrialised and non-industrialised countries. In Australia, majority of human disease outbreaks of Salmonellosis are associated with consumption of contaminated egg and egg products (OzFoodNetWorkingGroup, 2012, 2015).
Several intervention strategies have been implemented on a worldwide scale to reduce the risk of Salmonella contamination and has been discussed in the literature review. However, emergence of antimicrobial resistance (AMR) strains of Salmonella, egg contamination, biofilm formation and the decreased susceptibility of Salmonella biofilms to commonly used antimicrobials are the major obstacles in this journey. In spite of this, it is vital that studies concerning Salmonella must ensure the effective prevention and control of this zoonotic pathogen. This thesis has investigated different pathogenicity aspect of Salmonella enterica spp. recovered from egg farm environments of Australia and the key findings of in vivo and in vitro experiments are

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