Did you know that 70,000 to 80,000 alone in the United States of America are affected by sickle cell anemia alone? Stated from The United States National Library of Medicine. Also said by the United States National Library of Medicine 1 in 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans have the disease. Sad to say but my brother is a part of that 1 in 500 African American. Which one of the prime reasons I choose this topic. This disease is very severe and can cause excruciating pain and harm to someone's life.
What is sickle cell anemia? Sickle cell anemia is a severe hereditary form of anemia in which a mutated forms of hemoglobin (a red protein responsible for transporting oxygen in the blood of vertebrates. Its molecule
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When this happens, oxygen can’t reach nearby tissues. According to United Heart, Lung, Blood Institute. The sickle hemoglobin forms stiff rods inside the red blood cell forcing it to become a crescent shape cell.
Figure A shows normal red blood cells flowing freely in a blood vessel. The inset image shows a cross-section of a normal red blood cell with normal hemoglobin. Figure B shows abnormal, sickled red blood cells blocking blood flow in a blood vessel. The inset image shows a cross-section of a sickle cell with abnormal (sickle) hemoglobin forming abnormal stiff rods.
From real life example my brother has blood clot that he got three years ago in his leg. Due to him being sickle cell anemic is had yet to go away because of the lack of blood flow in his body. Also his leg has imploded.
As you can see his left leg doesn't have a blood clot but his right legs does. It is suppose to look identical to his left legs but because he has the sickle cell anemia disease his right leg has gotten so much bigger. This photo was taking 3 years ago. I don't have a current photo as of yet but his leg but due to the fact that the swilling never went down his left leg became worst as well. He his now schedule for
With red blood cells carrying mutant hemoglobin proteins, this means the red blood cells are deprived of oxygen. The red blood cells become sickle shaped. This means the red blood cells become more crescent shaped than round shaped. The sickle shaped red blood cells then clogs up and blocks blood canals. In the next paragraph, it will show how the sickle shaped red blood cells clog up blood canals. In the diagram to the right, it shows how mutated hemoglobin proteins are different. It shows that they get clumped up and stick together.
Sickle cell anemia is an anemia that is inherited and mostly affects people whose heritage can be traced back to places where malaria was prevalent. There are approximately 100,000 Americans that have the disease and many more with the trait. Several of my family members are afflicted by this medical condition that causes red blood cells to take on an irregular shape.
It is a condition in which there are not enough healthy red blood cells to carry adequate oxygen throughout the body. Red blood cells are normally round and flexible the moves easily throughout the blood vessels but, in sickle cell anemia the red blood cell is sticky, rigid, and has a crescent moon shape. The irregular shape cells can get stuck in the small blood vessels, which can slow or block
Each year in the US, an average of 75,000 hospitalizations are due to sickle cell disease, costing approximately $475 million. Sickle cell disease is also associated with significant mortality. Among children, the primary causes of mortality are bacterial infections and stroke. In adults, it is more difficult to attribute specific causes to mortality, but it appears that individuals with more indicative disease are at risk for early mortality.
Despite having so many opportunities of Sickle-Cell testing, our society still neglects the idea of
Sickle cell anemia (SCA) is an inherited disorder that produces sickle or crescent shape red blood cells. Thus, the mutated erythrocytes result in an inadequate supply of oxygen being transported throughout the body. Research shows that among those affected the most with the sickle cell gene are African Americans. In recent years, we have seen a decrease in mortality and morbidity rates as a result of new approaches to treating the disease. The more we understand the pathophysiology of sickle cell anemia, the more we learn about developing therapies for genetic disorders such as SCA. In this paper, we will briefly discuss what sickle cell anemia is and possible treatments for people with sickle cell anemia such as gene therapy and new drugs.
Sickle Cell Anemia is a disease that affects how oxygen is carried throughout the body by blood. Specifically, sickle cell anemia is characterized by a change in the shape of red blood cells from a smooth donut shape to a crescent or sickled shape. The sickled cells are very long and stiff, so many times
The term sickle refers to the fact that the red blood cells take on a sickle cell shape, instead of their normal biconcave shape (1). The cells can switch between the sickle shape and their normal biconcave shape (2). Sickled cells lose their pliability making it hard for the red blood cells to move through the smaller blood vessels (1). In their abnormal state they become more likely to adhere to the endothelium of the smaller vessels, causing clots to form and the possibility of stroke (2).
Approximately, two million Americans carry the sickle cell trait. 72,000 people are affected by sickle cell anemia in the U.S., most of whose ancestors had come from sub Saharan Africa, Spanish speaking regions, and Mediterranean countries such as Turkey, Greece, and Italy. In Hispanic American births, one in every thousand people acquire sickle cell anemia. The symptoms created by the blockage of blood flow can vary from patient to patient. Some have milder symptoms than others. Physicians use Hand-foot syndrome on patients to determine the disease. Sickle cells that clog small blood vessels in the hands and feet are one characteristic of the disease. Symptoms the patient suffers are swelling of the hands, feet and various joints. The pain
This paper outlines the etiology of sickle cell anemia and the nutrition considerations that is needed to maintain this disease. It also provides a five day menu plan that will greatly provide nutrition needs to prevent having a sickle cell crisis.
Sickle cell anemia has been a huge or major controversy in the united states ever since 1973 until today. It is an inherited disease that affects the red blood cells.
But, with severe pain crisis hospital provides morphine or oxycodone to help prevent the pain. Anemia is a very common complication of Sickle Cell Disease. When anemia occurs a person might have; pale skin, yellow skin, white eyes, slow growth, and delayed puberty. This brief paragraph will let a person know the main part about sickle cell. On how it is treated, the symptoms, and how it is cause. So, now when a person you know that has sickle cell you can let them know you learned a little about sickle cell to help their friend. I still think people with sickle cell disease still can have a regualer life all they have to do is watch what they do every time. Also, they will need to make sure that they are well hydrated at all times. Once you are not hydrated having sickle cell can be the worse thing because of the pain and how bad it comes. Sickle cell diesaes doesn’t ruin one person life it just take that one person know what they can do and cant do at all times. There are doctors that help with sickle cell too. These doctors’ helps you maintain your pain crisis and let you know what you can and cannot do at
This paper will discuss Sickle Cell Anemia. It will describe what the disease is as well as how its contracted. The paper will go on to on to discuss the symtoms risk and statistics of sickle cell aniema. The paper will end with discussing treatment for the disease.
The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease.
Sickle Cell Anemia is a disease that affects how oxygen is carried throughout the body by blood. Specifically, sickle cell anemia is characterized by a change in the shape of red blood cells from a smooth donut shape to a crescent or sickled shape, almost the same shape as a crescent moon. The sickled cells are very long and stiff, so sometimes