Case Study: A 45-year-old woman, otherwise healthy, presents with the following symptoms:
Itchy eyes
Difficulty swallowing
Problems eating
Mouth sores
Mouth pain
Fatigue
Swollen glands
According to the symptoms presented in this case study, I would give a suggested diagnosis that the woman may have Sjogren Syndrome.
Sjogren syndrome is an autoimmune disorder in which the gland that produce tears and saliva are destroyed, which causes dry mouth and dry eyes. This condition may affect other parts of the body like your lungs and kidneys, suggests Starkebaum (2015). Although the cause of this autoimmune disorder is unknown, it causes the body attacks your healthy tissue by mistake. It’s very rare in children, but it occurs most often in women ages 40-50. If you have another autoimmune disorder such as Polymyositis, Rheumatoid Arthritis, Scleroderma, or Systemic lupus erythematosus, Sjogren Syndrome can occur with any of these autoimmune disorders (Starkebaum, 2013).
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There is a higher risk for Lymphoma when Sjogren Syndrome has been very active for a long period of time (Starkebaum, 2015). It has been estimated that people with Sjogren's syndrome are 44 times more likely to develop non-Hodgkin’s Lymphoma than people without the condition (NHS Choices, 2014). According to NHS Choices (2014), while this increased risk may sound alarming, the chance of a person with Sjogren syndrome developing non-Hodgkin Lymphoma is still small, as it only affects around 5% of people with the syndrome. However, if you have this autoimmune disorder, you should be aware of the main early symptom of non-Hodgkin Lymphoma, which is a painless swelling in a lymph node (gland) - usually in the neck, armpit or groin. In Sjogren syndrome, when lymphoma develops it often involves the salivary glands. Persistent enlargement of the salivary glands should be investigated further (NHS Choice,
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the
Lupus is a chronic, autoimmune disease that causes swelling, pain, and inflammation throughout the body. An autoimmune disease is when the white blood cells inside a person’s body cannot tell the difference between healthy tissue and foreign invaders. That cause the white blood cells to attack and kill the tissue in body systems, including organs like the heart, brain, lungs, and kidneys. When diagnosing for lupus it is extremely difficult. This is because the signs and symptoms of Lupus often imitate those of other diseases. The sign that differentiates Lupus from other diseases, is a facial rash that resembles a butterfly across the cheeks and nose. This is an often seen sign but it doesn’t always occur. There are several types of Lupus including
Since this disorder is not inherited, someone may not know they have the disease until they experience facial paralysis. Bell’s Palsy affects both men and women equally and targets people between the ages of 15-60. “About 1 in 60 people have a Bell’s Palsy at some stage in their life.” The inflammation of the facial nerve could have been caused by viral infections such as by the herpes simplex, or cold sore, virus or by the varicella-zoster, or chickenpox, virus. Scientists believe that children who have had these viruses and recovered physically, may not have gotten completely rid of the virus internally. While the virus is still floating around within the body, it usually remains inactive although, sometimes it becomes re-activated. The re-activated virus is the known to target the facial nerve causing it to become inflamed and result in the unilateral facial paralysis, Bell’s Palsy.
Using this and internet research, the team came to a conclusion: this woman was experiencing Malaria caused by Plasmodium vivax. This conclusion was reached through a couple of steps. First of all, the biologists learned that mefloquine often is used to treat Malaria (“Mefloquine”), which was the first hint to the type of
The most common signs and symptoms of Sjögren’s syndrome were kerato-conjunctivitis sicca (xerophthalmia), dry nose, dry mouth (xerostomia) that can lead to a dry cough, multiple dental caries, difficulty swallowing and chewing, difficulty speaking, swollen salivary glands and white tongue combined with fatigue and severely reduced the quality of life. Furthermore, a patient with Sjogren’s syndrome can suffer from dry skin.5,6 diffuse pain and fibromyalgia are also present in five percent of primary Sjögren’s syndrome (pSS). 1, 2
In general Arthritis describes that inflammation that occurs in the joints which can be warmth, redness, pain and/or selling. RA is an ongoing type of arthritis, the symmetric involvements of joints differentiates RA from other arthritis types. normally when one side is effected the other side most likely is also effected such as both knees, hand or/and wrists. Patients with rheumatoid arthritis suffer from Joint pain, stiffness, fatigue etc which can effect their quality of life. In addition to medications clinicians must educate patients on Non-pharmacologic approaches to aid in relief such as the following
She has difficulty with reading and writing and she mixes words when talks. She loves to listen to music and old religious scriptures. She also has problem with her knees, shoulder and neck since 2 years ago. Her knee pain is better with a motion and with a massage therapy. She is chilly person, with not much thirst. She drinks hot milk every morning. It was also reported that she is very sensitive to anything that is depressing or sad and after the accident it got worse. She is very sensitive to touch. Her teeth are sensitive to cold drinks. In 2012 she experienced some heartburn issues, but took some prescribed medication and issue went away. There is no food preferences, no problem with digestion or bowl movement. Menstrual cycle were normal, no cramps, everything normal, 2 normal pregnancies (as reported by her husband). Almost at the end of the interview her son reported that when Iqbal takes a walk on the city street, very often she confused the white lines with some big obstacles. When
SLE is a potential disease that is treatable once properly diagnosed which could help with removing the risk of misdiagnosis with possible implication of more health problems resulting from the misuse of certain prescription drugs. “Elderly-onset SLE is associated with lower survival,” which is why knowing the signs and symptoms learned through health promotion is important to the geriatrics. A recent study included the older population diagnosed with SLE to show the affects of age on their signs and symptoms. The older group had a more discoid lupus, photosensitivity, and pulmonary fibrosis with a similar incidence of malar rash, alopecia, arthritis and polymyalgia and lower reported incidences of oral ulcers, Raynaud’s phenomenon, cutaneous vasculitis, and leukopenia (Dimant, pp. 58-61). The group of older patients also needed a lower dose of the corticosteroids and a shorter azathioprine therapy course, which suggested that when SLE was caught early on in an aging patient it was milder with a better response to therapy and treatment. This would support other research that states, “correct diagnosis and treatment of elderly-onset lupus may improve morbidity” (Fettig, 2013, pp. 1634-1635). This simple hindsight would help with awareness in not just aging adults but in physicians as
Millions of people around the world suffer from incurable, autoimmune diseases. Even with the tremendous advancement in medical field, there are many questions unanswered. More and more diseases of unknown cause are being evolved every now and then, which are threatening to the mankind. Systemic lupus erythematosus (SLE) is a classic example of such a disease. SLE is a chronic, often life-long, autoimmune condition, ranging from mild to severe in severity. SLE may affect many organs in the body, including but not limited to kidneys, skin, joints, respiratory and nervous systems. The name of this disease describes it; word systemic indicates the widespread involvement of various tissues and organs of the body. Lupus is a word derived from Latin language, which means wolf, referring to the rash on the face which was thought to resemble a wolf bite. Erythematosus is a Greek word, meaning red, referring to the color of the rash.
Diagnosis involves a complete medical history and physical examination but since symptoms of Sjögren’s mimic other conditions and diseases, Sjögren’s can often be disregarded or misdiagnosed [3]. In some cases, the doctor may want to biopsy the saliva glands. Although many patients experience dry eyes and dry mouth, Sjögren’s also cause dysfunction of organs such as the kidneys, gastrointestinal system, blood vessels, lungs, liver, pancreas, and the central nervous system. There is also a higher risk of developing lymphoma and as many as four million Americans are living with this disease. With up to four million Americans suffering from Sjögren’s, it is one of the most prevalent autoimmune diseases. Nine out of ten patients are women and on average, it takes nearly three years to receive a diagnosis of Sjögren’s
If the woman has joint pains associated with swelling, restricted movements of the joints along with the fever then should immediately consult the doctor.
A rare and serious disease that is uncommonly associated with Sjögren's syndrome is primary biliary cirrhosis, an autoimmune disease of the liver that leads to scarring of the liver tissue.
Eye Symptoms: Rheumatoid arthritis can attack the eyes, causing pain, dryness, and inflammations, including uveitis, episcleritis, and iritis. Some of your eye symptoms may be caused by Sjogren’s syndrome, a disorder that causes dry mouth and
A cross-sectional study included 100 SLE patients fulfilling the American college of Rheumatology (ACR) revised classification criteria for SLE(8). All patients were recruited randomly from the Rheumatology outpatient clinic and the inpatient ward of Internal Medicine and Rheumatology department at Ain Shams University hospital. The nature of the present study was explained to all participants. The laboratory
Have you ever noticed what is Sjogren’s Syndrome? If not, have you ever suffered from dry eyes or dry mouth? Or even worse some respiratory problem like chronic cough or digestive problem such as loss of appetite?