Prevalence Of M. Tuberculosis Infection

Tuberculosis is caused by the bacteria “Mycobacterium Tuberculosis” and is mainly causes infection of the lungs (WHO, 2016). Its mode of transmission is airborne, so it can be passed on by inhalation of airborne droplets which carrying the bacteria, when an infected patient coughs, sneezes, or spits the TB germs into the air (WHO, 1026). Among the symptoms of active TB are: cough with sputum and blood, chest pains, weakness, fever and night sweats (WHO, 2016). Most at risk to get the TB infection are people with weakened immune system such as people who are suffering from chronic diseases such as diabetes mellitus, severe kidney disease, silicosis and especially HIV infection (CDC, 2016). Children and Tobacco users are also at greater risk to fall ill with TB.

There are many tests are available to diagnose SLE. The tests available are antinuclear antibody (ANA), complete blood count (CBC), chest x-ray, serum creatinine, and urinalysis [24]. CBC is used to check red blood cells, white blood cells and platelet level which are typically abnormal in patients with SLE [24]. Urinalysis checks for kidney function, measuring the levels of protein and check for any urinal tract infection [68]. A complete physical is also conducted and the heart is checked for abnormal sounds or friction rubbing [24]. To classify a person with SLE, physicians abide to the American College of Rheumatology (ACR) criteria list, in which 4 out of the 12 criteria must be present in a patient and this shows a specificity of 95%

The book “She Said Yes”by Misty Bernall is a story about a girl who died for believing in Christ. Cassie Bernall was born in Colorado on November 6, 1981. Cassie was a student at Columbine High School when the tragedy occurred. Cassie died on April 20, 1999 at the age of 17 by a gunshot. Cassie was claimed to be shot by two of her fellow students, Eric Harris and Dylan Klebold. Cassie showed everyone how strong of a Christian she was by answering “yes” to the question the two shooters asked her, “Are you a Christian?” What would you have answered?

The diagnosis of SLE is difficult. Autoimmune diseases are a group of related conditions that present similar symptoms. One autoimmune disease is not a unique disease with its own unique symptoms, instead autoimmune diseases are a group of related conditions (see fig 2 and table2). Currently there are no definite number of how many autoimmune diseases exist, however, there is a range of autoimmune diseases that varies from 80 to as many as 120 (EHP,

TB infection is transmitted through air by droplet nuclei that contain M. tuberculosis complex. Droplets are expelled when infected patients exhale, cough or sneeze. When the tiny bacilli are inhaled, they reach alveoli at lungs and start to multiply. TB infection may develop TB disease as bacilli can pass through blood, lymph nodes and other parts of the body. Miliary or disseminated disease occurs when large numbers of M.tuberculosis attack other organs and tissues such as bones, kidney, female reproductive system and nervous system. World Health Organization1 reported that South-East Asia Region has the highest TB incidence rate (3.2 million cases) in the world, while The Americas region has the lowest rate (280000 cases). Approximately 1.3 million of people died from TB in 2008 and the highest mortality was in South-East Asia Region1. Table 1 shows that Australia is one of the countries that has the lowest TB cases; in 2007, 1300 cases were reported and the mortality rate was 100 per year5; in 2008, 1400 cases were reported1. Table 2 shows that Vietnam has much higher number of cases in

Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover the increasing prevalence of HIV-AIDS and diabetes mellitus is being proved to be providing predisposition to tuberculosis. As witnessed by the WHO, which has estimated that, in the year 2012, 8.6 million people have developed tuberculosis and 1.3 million have died of the disease including 320000 deaths of HIV-TB co-infected people (Global tuberculosis report 2013. World Health Organization; 2013). Long term antibiotic therapy and that too associated with several side effects and discomforts have diminished patient compliance with the anti-tubercular chemotherapy. This fact in turn has raised the new deadlier MDR-TB and XDR-TB strains. The whole scenario is a matter of panic and questioning the effectiveness of anti-tubercular antibiotics, immunologic efficacy of century old BCG vaccine and all other medical advents.

In the 19th century, England was known for its horrific labor laws and employment of children. The rules had stated that an employer could schedule their under-aged employees to work in any time of day, as long as they provided at least 2 hours of education. While the public had believed that these children were being educated and employed, factory owners ignored the fact that mortality rates in children were rising and that the education those children were receiving was extremely poor. The laws intentions were to allow children to receive proper schooling because at the time kids working in factories did not have the time to receive a proper education. The laws on education for children in the workforce may have seemed to help families and

All patients fulfilled at least four of the revised classification criteria for SLE of American College of Rheumatology (ACR) as described in table ()

Canada has had many events where tuberculosis was having an outbreak in 1924 through 1948, but since then it has been decreasing. We have dealt with this problem back in 2012 where an outbreak of tuberculosis infected 8% of the individuals in the extremely small Northern Quebec community of Kangiqsualujjuaq. After the outbreak The Public Health Agency of Canada is running over to discover the origin of the outburst its spread. Officials are also bringing up more additional resources to the place, such as a mobile x-ray machine. Tuberculosis is a disease caused by bacteria that travel from person to person. A person who is infected with tuberculosis, but does not show any symptoms at all may have dormant tuberculosis and can still transmit

Communicable Disease Paper Tuberculosis  Communicable diseases rely on fluid exchange, contaminated substance, or close contact to travel from an infected carrier to a healthy individual. Many people have never heard of a disease called tuberculosis (TB) or not fully aware how serious this disease really is. I will briefly summarize the research that was conducted on tuberculosis by describing the disease in details and discussing efforts to control it, indentify environmental factors related to tuberculosis, and explain the influence of lifestyles, socioeconomic status, as well as disease management. I will also briefly describe what public health departments are doing to reduce the threat, and include data, evidence, and plan to

SLE may cause a wide range of neurological and psychiatric symptoms including those due to central, peripheral and autonomic nervous system and different psychiatric syndromes. In 1999, the ACR developed a standardized nomenclature system for the NP syndromes of SLE for the purposes of classification and reporting (The American College of Rheumatology, 1997; 1999). It distinguishes three subsets of syndromes: psychiatric disorders, cognitive deficits and acute confusional states; neurological syndromes of the CNS and neurological syndromes of the peripheral nervous system (The American College of Rheumatology, 1997; 1999). Anxiety,

Miliary pattern on the chest radiograph is often the first clue ,revealing of miliary TB.

In particular: a) species which show no aging (“animals with negligible senescence”) show the same telomerase activity at any age and have no cancer problem, as demonstrated by their constant mortality rate at any age; b) in our species, studied in wild conditions, the increase in age-related mortality is precedent to cancer-related deaths cases and it is impossible that defenses against cancer kill before cancer can develop; c) shortened telomeres, as a result of telomerase inactivity, cause dysfunctional telomere-induced instability and so the likelihood of cancer increases; d) in normal mice, telomerase expression delays aging but does not increase cancer risk.

This study was conducted on thirty adult patients with SLE Patients were selected from rheumatology outpatient's clinic of AL-Zahraa hospital, Cairo, Egypt, during the period from June 2015 till October 2016. SLE patients fulfilling the American College of Rheumatology (ACR) revised criteria for the diagnosis of SLE were included11. Patients with clinical manifestations of SLE such as malar rash, photosensitivity, alopecia, oral ulcers arthritis, nephritis, neuropathy and hypertension were included in the study. Current medications were recorded , Patients with diabetes mellitus, malignancies and those with a diagnosis of mixed connective tissue disease were excluded. The study also included thirty age and sex matched apparently healthy

To increase TB detection, Georgia introduced laboratory diagnosis of tuberculosis and MDR-TB detection technologies in 2011. This helped to detect approximately 63 percent of MDR-TB cases. However, one-third of patients with MDR-TB remains undetected and represents a source of TB infection. Despite universal access to MDR-TB treatment, almost third of patients do not undertake treatment. Also every tenth case of detected TB is qualified as MDR-TB (USAID Georgia Tuberculosis Prevention Project, 2013). For these reasons, Georgia remains a high burden country for MDR TB (Partnership for Social initiatives , 2013)