The Treatment Of Sickle Cell Anemia Essay

2059 Words9 Pages
The treatment of sickle cell anemia with high concentrations of fetal hemoglobin with correct bacterial strain

Brandon Frey, Sebastian Dziadowicz, Jeremy Eckels, David Lyons
November 17, 2016

Table of Contents
Cover Page…………………………………………………………………. 1
Table of Contents…………………………………………………………… 2
Executive summary…………………………………………………………. 3
Introduction…………………………………………………………………. 3-4
Methods…………………………………………………………………....... 4
Results and Discussion……………………………………………………… 4-6
Summary and Recommendations…………………………………………… 6-7
Works Cited…………………………………………………………………. 8
Appendix 1....................................................................................................... 9
Appendix 2…………………………………………………………………... 10
Appendix 3…………………………………………………………………… 11

Executive Summary:
Sickle cell anemia is a disease that is caused by abnormal hemoglobin. The abnormal hemoglobin syndicates with other abnormal hemoglobin molecules to cause rigid distortion of red blood cells. HbF or fatal hemoglobin is a crucial modifier of the severity of sickle cell anemia. An organism was produced that yields a high concentration of HbF, which is used to help treat sickle cell anemia. To determine the organism, total protein was isolated and an enzyme analysis was preformed using spectrophotometry, sequences of the strains were analyzed to conclude which stain produced beta-galactosidase under various nutrient conditions, and cells were observed with and without plasmids
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