Tissue Regeneration And Healing : A New Standard For Healing And Repair

Questions 1. What is the cellular and molecular basis of non-healing wounds and ulcers? Fig 1; courtesy of google image “The most common types of non-healing wounds are pressure ulcers, diabetic ulcers, ischemic ulcers and venous ulcers.” (2) In the case of a non-healing wound, the order of the healing process may be blocked or interrupted at any of the above stages; especially at the inflammatory or proliferative stage. The mediators of this arrest may include an impairment of the inflammatory

1) define and explain the concept of Guided tissue regeneration(in detail) (GTR) According to the Glossary of Periodontal Terms 4th Edition, Guided tissue regeneration is defined as “Procedures attempting to regenerate lost periodontal structures through differential tissue response.” The concept of Guided tissue regeneration is centered on placing physical barriers to block the apical migration of the gingival connective tissue and epithelium cells of the flap, while allowing the inward migration

Bone regeneration is a complex, well-orchestrated physiological process of bone formation, which can be seen during normal fracture healing, and is involved in continuous remodelling throughout adult life. However, there are complex clinical conditions in which bone regeneration is required in large quantity, such as for skeletal reconstruction of large bone defects created by trauma, infection, tumour resection and skeletal abnormalities, or cases in which the regenerative process is compromised

type of tumour involved. Working in long term care facility like Rest Home in New Zealand, common skin problem in elderly are skin carcinomas. Typical treatment for superficial BCC in rest home a setting are cryotherapy, topical creams (imiquimod) and lastly, is excision surgery thus it will be an advantage to focus on this treatment method. This assignment discuss the pathophysiology of basal cell carcinoma, wound healing, and factors contributing to carcinogenesis. There are varieties of treatment

tooth follicle or prevention or repair of periodontal defects in adjacent second molars (L2Ms), have been suggested for surgical extraction of 3Ms.(1) A partially impacted L3M exposed to the oral environment is more susceptible to periodontal infection and thus to greater periodontal attachment loss.(2–5) Similarly, deeply impacted L3Ms often leads to periodontal defects after its surgical removal.(6,7) In this sense, several studies have shown that periodontal healing of the 2Ms after 3M removal is

which a deficiency or excess of energy, protein, and other nutrients causes measurable effects on tissue and body structure and function (Leaker, 2013). Malnutrition has many effects on the body, including impaired organ function, impaired collagen synthesis, impaired immune function, and reduced antioxidant activity. Impaired organ function can reduce the body’s oxygen supply, which depletes tissues of needed oxygen and nutrients. Impaired collagen synthesis decreases the tensile strength of the

substitutes is a biocompatible material that used to promote a bone defects healing by providing a biologic response to the local site [45]. In orthopedic surgery, exposure to a severe injury commonly requires surgical intervention to compensate and repair the defected site. Bone grafts often need to replace the lost part principally in critical bone size defect, with which the reconstructive process will be enhanced by supporting the tissue growth. Replacement techniques are varied based on using a conventional

missing tissue, when a primary surgical wound becomes infected and partially or fully dehiscence or a wound is purposely left open after surgery to heal by connective tissue repair. Tertiary intention surgical wounds are wounds that are purposely left open post-surgery with the intention to return for a surgical closure. (See Apendeices A) is a visual chart of primary secondary and tertiary wounds. Sometimes drainage devices are used in surgical wound care for drainage and to improve healing process

A new way to grow bone When we think of bone it sounds like it is hard to grow and that is true too. Bones are the hardest components of our body. It is made of calcium laid down by stem cells. In children, cells at the end of epidermises add new calcium to the network of the bone and that grows over time. So, the children have that epiphyseal plate that grows and becomes narrow when they reach up to their adult height. The Ted talk by Molly Stevens on ‘A new way to grow bone’ was

environment and internal tissue [1]. According to medical dictionary, breaching of skin or underlying tissue due to any accident, act of violence or surgery is called as wound [2]. Following an injury, the skin has a tremendous capacity to heal. When skin get injured, the repair process entails removal of the damaged tissue and laying down of a new extracellular matrix (ECM) over which epidermal continuity can be reestablished [3]. To promote wound repair and regeneration,