Tuberculosis Cohort Review Policy
1.0 POLICY
By the direction of the Nevada Division of Public and Behavioral Health, Tuberculosis Elimination, Prevention and Control Program, all state and local health authorities will participate in Tuberculosis (TB) cohort reviews.
2.0 PURPOSE
The purpose of this policy is to ensure that all persons with active TB in Nevada receive appropriate evaluation and treatment; to track progress toward meeting state, local, and national program objectives; and to clarify the roles and responsibilities of state and local TB programs.
3.0 SCOPE
This policy covers common terms and abbreviations used in TB, as well as the procedure related to conducting cohort reviews.
4.0 DEFINITIONS
Common Terms
Cohort – a
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The end date of an infectious period is determined by the date that the person with TB disease was placed in airborne infection isolation (AII). Household contacts may have an infectious period duration counted until the index has taken 2 weeks of anti-tubercular medicines.
Initial Phase – the first phase of TB treatment (usually 2 months) treated with 3 therapeutic anti-tubercular medicine.
Smear (AFB smear) – a laboratory technique for preparing a specimen so that bacteria can be visualized microscopically. The quantity of stained organisms predict infectiousness. The amount of bacteria seen is graded as: No AFB, Rare, or 1+ to 4+ AFB.
Common Abbreviations
AFB – Acid Fast Bacilli
BCG – Bacille Calmette-Guerin
CXR – Chest X-ray
DOT – Directly Observed Therapy
100% DOT – Doses observed Monday through Friday via DOT
EDN – Electronic Disease Notification
EMB - Ethambutol
IGRA – Immune Globulin Release Assay
INH - Isoniazid
LTBI – Latent Tuberculosis Infection
PZA - Pyrazinamide
QFT – QuantiFERON TB
RIF – Rifampin
RIPE – Rifampin, Isoniazid, Pyrazinamide, Ethambutol
SAT – Self Administered Treatment s/sx – Signs and Symptoms
TST – Tuberculin Skin Test
Tx - Treatment
5.0 PROCEDURES
Cohort reviews will be conducted annually in each county and/or jurisdiction. Reviews can be conducted face-to-face or by
Current treatment of this disease is a complex, long process. Because of TBs notorious background of being resistant to many drugs, treatment usually consists of an antibiotic regimen lasting upwards of 6-12 months. Treatment also varies from individual to individual. Age, health, TB form, and location of infection all impact the type of treatment one is given to aide in curing the disease (MayoClinic, 2014). Regardless, treatment of this disease is not an easy task for many reasons. Compliance and patients tolerance to such a strict medication regimen for a prolonged period of time is a huge variable which decreases the likeness of successful treatment related to increased occurrences of medication side effects and missed dosages. According to World Health Organization
While tuberculosis was never completely eliminated, there was a significant drop in cases and death rates, as a result of the BCG vaccine and new anti-tubercular drugs in the 1950’s.
The Yuma County Health Department has a tuberculosis program that is funded on a federal, state, and local level (Yuma County Health Department, 2016). Yuma County has developed this program to combat the incidence of tuberculosis within the community. However, the program has some limitation regarding its availability. Lack of funding has resulted in skin test screening being restricted only potentially infected or high-risk clients (Yuma
Boire, et al. (2013) claim that diagnosing active TB is important, however, how to prevent LTBI is also vital. Toyota, et al. (2010) claim that early detection and treatment is crucial to ending the TB epidemic. Using the Interferon-Gamma Release Assay (IGRA) test would be a good solution for early detection for not only the elderly population but also the most productive populations (Toyota,
Tuberculosis is a disease of an infectious nature caused by a bacterium known as mycobacterium tuberculosis. The disease spreads through the air. People with the disease can spread it to susceptible people through coughing, sneezing, talking or spitting. It mainly affects the lungs and other parts such as the lymph nodes and kidneys can also be affected. The symptoms for TB are fatigue, coughing, night sweats, weight loss and fever. One third of the population of the world is affected with mycobacterium tuberculosis. The rate of infection is estimated to be one person per second. About 14 million people in the world are infected with active tuberculosis. Drug resistant TB has been recorded to be a serious public health hazard in many countries. Resistant strains have developed making it difficult to treat the disease. TB has caused millions of death mainly in people living with HIV/AIDS ADDIN EN.CITE Ginsberg19981447(Ginsberg, 1998)1447144717Ginsberg, Ann M.The Tuberculosis Epidemic: Scientific Challenges and OpportunitiesPublic Health Reports (1974-)Public Health Reports (1974-)128-13611321998Association of Schools of Public Health00333549http://www.jstor.org/stable/4598234( HYPERLINK l "_ENREF_3" o "Ginsberg, 1998 #1447" Ginsberg, 1998). The World Health Organization came up with the DOTS (Directly Observed, Therapy, Short course) strategy. The approach involves diagnosing cases and treating patients with drugs for about 6-8
Now, we will see what the most optimal solution to this recent problem in the classic epidemiological way, by understanding the history of TB, the drug-resistant strain’s origin, and recent cases of the disease.
Tuberculosis (TB) is brought on by a bacterium called Mycobacterium tuberculosis. The microorganisms more often than not assault the lungs, however TB microbes can assault any part of the body, for example, the kidney, spine, and mind. Not everybody infected with TB microbes gets to be sick. Therefore, two TB-related conditions exist: latent TB infection (LTBI) and TB infection. If not treated legitimately, TB can be deadly (CDC, 2016). TB microbes are spread through the air starting with one individual then onto the next. The TB microorganisms are put into the air when someone with TB illness of the lungs or throat coughs, talks, or sings. Individuals adjacent may take in these microscopic organisms and also become ill (CDC, 2016). Individuals with TB are well on the way to spreading it to individuals they invest time with consistently. This incorporates relatives, companions, and coworkers or classmates.
Canada has had many events where tuberculosis was having an outbreak in 1924 through 1948, but since then it has been decreasing. We have dealt with this problem back in 2012 where an outbreak of tuberculosis infected 8% of the individuals in the extremely small Northern Quebec community of Kangiqsualujjuaq. After the outbreak The Public Health Agency of Canada is running over to discover the origin of the outburst its spread. Officials are also bringing up more additional resources to the place, such as a mobile x-ray machine. Tuberculosis is a disease caused by bacteria that travel from person to person. A person who is infected with tuberculosis, but does not show any symptoms at all may have dormant tuberculosis and can still transmit
TB is a major cause of mortality and morbidity globally that boils down to one small, single infection. TB can be classified into 2 stages; Latent TB and Active TB. In Latent TB, the bacteria remain in the body in an inactive or dormant state. A person will not have any symptoms because their immune mechanism has stopped the bacteria from growing. Latent TB can remain in a dormant state for year (Zager et al, 2009). However this disease can easily change to Active TB. This change mainly occurs due to the rapid increase of Mycobacterium TB within an individual when a person becomes ill or their immune system is compromise. Ninety percent of the time, those who are infected with
Little was known about treatment and prevention of the disease at that time. It was not until 1953 that the United States began collecting data and reports on the 84,304 new cases of TB. This data could be used in research. TB was recognized as a preventable deadly disease, and a common goal to eradicate TB was adopted. Over the next 32 years, the new TB cases dropped 74%. By 1985, there were only 22,201 TB cases. History notes that law makers and public health officials became complacent and thought they had found the solution for eradicating TB. Resources for TB surveillance, prevention, and treatment options were reduced, while homeless numbers increased. This changed history as from 1985 to 1992 TB rates started to increase. Data collected from demographic regions and surveillance records show TB cases rose by 20% in those seven years to equal new 26,673 cases, and the estimated number of TB cases (old and new cases together) during that time was more than 64,000 cases. This was the last recorded peek in TB history. Since 1992, there has been a decrease of 67% in all TB cases. Studies reflect this decrease from 10.5 to 3.4 per 100,000 persons. Much credit for this continued decline is attributed to state and federal aid in addition to the state and local programs aimed at fighting TB and the helping the homeless population. Continued public education, proactive surveillance,
Active disease is diagnosed with chest x-ray, skin or blood tests and sputum smears. Cat scans and MRI’s can also be used for diagnosing. Treatment for active non-resistant TB consists of the use of a two drug therapy, generally isoniazid and rifampicin. Cure rate for this strain of TB can be over 90%. Treatment for active TB is done for a minimum of six months. As a result of individuals incompletely finishing their recommended dose of anti-tubercular
The Primary goal of the study was to examine the distribution of DM among TB patients and explore the risk of Drug resistant TB in Diabetics who are also infected with TB in Florida, USA. The Florida department of health TB control program aims to eliminate TB in the state through TB care initiative, A Florida system of Tuberculosis care formed by partnership between the Florida Department pf Health (FDOH) and the public health system statewide to ensure availability of effective TB management program, an aim in line with the global plan to stop TB 2016-2020 adopted by WHO has a post 2015 strategy to eliminate TB as a global epidemic by 2035.
Tuberculosis (TB) is a chronic bacterial infection that affects millions of people globally. It is a contagious disease that is spread through the air, and it usually affects the lungs. It is transmitted from person to person through droplets from the respiratory tract of those who are already infected with the disease. Some who are infected with the bacteria that causes TB often exhibit no symptoms, because their immune systems stop the bacteria from growing and multiplying. Those with compromised immune systems are more susceptible to developing the full blown disease which can cause symptoms that include coughing, spitting blood, chest pains, weakness, weight loss, and fever. Tuberculosis can be treated with a six to nine month course of a combination of antibiotics. If left untreated, TB will spread and can be fatal.
TB is caused by a bacterial infection known as mycobacterium tuberculosis. If a patient is sick with TB is considered a disease. The infection is prevalent in the HIV population because approximately 13 million Americans are effected by the TB bacteria. It typically involves the lungs but can also affect the brain and other organ systems. The TB germ is airborne and can live in the air for several hours. Once an affected person coughs or sneezes another person breathes in the germ and becomes infected. A patient with TB and HIV/AIDS will have to take an antibiotics long term to battle the infection. They will have to go through two phases of medication. The initial phase consists of utilizing drugs such as isoniazid, pyrazinamide, rifamycin, and ethambutol for the first couple of months. Then the patient will enter into the continuation phase, during this phase the patient will take the isoniazid and rifamycin for approximately four months. HIV patient’s that are taking antiretroviral for the HIV will have to take the antibiotics longer. A person taking treatment for TB has to be careful because the antibiotic can cause liver damage. According to the CDC, roughly 6% of all TB cases are from patients with HIV or AIDS. In 1992 the United States had a dramatic increase in TB cases but has decreased ever since. Recently a group of researchers at John Hopkins
India, the second most populous country with over 1.31 billion people, has the highest burden of tuberculosis (TB) in the world, accounting for 20% of the global incidence of TB, and an even higher share of global incidence of multi–drug resistant (MDR) TB. With an estimated 2 million new cases of TB and 5, 00,000 TB-related deaths in India annually, those who got diagnosed with different forms of DR-TB were 35,385 cases but only 20,753 people started on multidrug-resistant TB (MDR-TB) treatment in 2013. The National Tuberculosis Program was launched in 1962, but suffered heavily continuing TB led mortality. Acknowledging this reality, a Revised National Tuberculosis Control Programme (RNTCP) was launched by the Government of India in 1997, however even today it does not comply with World Health Organization (WHO) recommendations.