Types Of Multiple Organ Dysfunction Syndrome

1759 Words Mar 13th, 2016 8 Pages
Introduction
Multiple Organ Dysfunction Syndrome, also known as MODS, can occur after any severe injury or disease process that activates a large systemic inflammatory response which includes any kind of shock (Sole, 2013, 283). Like with any kind of dysfunction, organ dysfunction can lead to further organ failure and ultimately death (Sole, 2013, 283). The most common causes of MODS includes severe sepsis and septic shock, which represents the highest cause of mortality in these conditions (Semeraro, 2011, 293). The body’s immune system along with the body’s response to stress can be a precipitating factor to maldistribution of circulating volume, global tissue hypoxia, and metabolic alterations which results in damage to the organs (Sole, 2013, 283). According to Ignatavicius (2013), once the damage has begun, a vicious cycle follow resulting in further cellular and organ damage. The first organs to lose their function include the liver, heart, brain, and kidneys, with the most devastating change being the damage to the heart muscle (Ignatavicius, 2013, 814). Multitudes of research has been done to further explain the cause and possible treatments for this deadly syndrome.
Pathophysiology
MODS can classified as either primary or secondary. According to Sole (2013), Primary MODS is a result of an injury to a specific organ which can occur in shock, trauma, burns, or infection that causes an impairment in the perfusion of blood that can either be localized or systemic,…
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