1) LDA 2) CH,I

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter23: Addition To A Carbonyl
Section: Chapter Questions
Problem 14E
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When the ketone shown below is treated with LDA, followed by CH3I, the product shown is isolated from the reaction mixture.
1) LDA
LDA
2) CH,I
Propose a curved-arrow mechanism for this reaction. Use curved arrows to show movement of electron pairs, and draw structures
for all important reaction intermediates. If an intermediate is a resonance hybrid, it is only necessary to draw the MOST IMPORTANT
contributing resonance structure. Be sure to show all lone pairs and nonzero formal charges. For reference, the structure of LDA is
shown next to the overall transformation.
Transcribed Image Text:When the ketone shown below is treated with LDA, followed by CH3I, the product shown is isolated from the reaction mixture. 1) LDA LDA 2) CH,I Propose a curved-arrow mechanism for this reaction. Use curved arrows to show movement of electron pairs, and draw structures for all important reaction intermediates. If an intermediate is a resonance hybrid, it is only necessary to draw the MOST IMPORTANT contributing resonance structure. Be sure to show all lone pairs and nonzero formal charges. For reference, the structure of LDA is shown next to the overall transformation.
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