1- Name of the disease/metabolic disorder due to deficiency of propionyl CoA carboxylase enzyme 2-Population affected; gender, age, race ... etc affected by previous disease or disorder 3- Symptoms of the disease/metabolic disorder (maximum 3 - 5 main common symptoms)
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- Describe the role of ethanol in cellular energy supply, the metabolism of ethanol (alcohol), the regulation of its metabolism and the disease conditions associated with its metabolism especially - hypoglycemia, ketoacidosis, hepatic steatosis, Vitamin deficiency, and acetaldehyde toxicity (you should feel free to discuss other diseases that are directly related to ethanol metabolism).Indicate what will happen ( increase, decrease or no effect) tothe activity of the enzyme or rate of the metabolic pathway in the given conditions a. release of glucagon in the blood to the activity of carnitine acyl transferase 1 b. high malonyl CoA to the activity of carnitine acyl transferase I C. Epinephrine to the activity og glycogen synthase d. high citrate to the activity of acetyl CoA carboxylase e. high acetyl CoA to ketogenesisIndicate what will happen ( increase, decrease or no effect) a. release of glucagon in the blood to the activity of carnitine acyl transferase 1 b. high malonyl CoA to the activity of carnitine acyl transferase I C. Epinephrine to the activity og glycogen synthase d. high citrate to the activity of acetyl CoA carboxylase e. high acetyl CoA to ketogenesis
- A patient who has been drinking large amounts of alcohol for long periods of time shows thefollowing symptoms: apathy, loss of memory, and a rhythmical to-and-fro motion of the eyeballs.Which of the following reactions are most likely to be affected in the patient? A. Conversation of pyruvate to acetyl-CoA B. Conversation of a-ketoglutarate to succinyl-CoA C. Both A and B D. Neither A nor BWhat is the most dangerous adverse effect following use of biguanides?A. Lactic acidosisB. HypoglycaemiaC. Diabetic ketoacidosisD. HyperosmolalityE. Hyperglycaemia[Alphabetical order] Name all of 7 ketogenic acids that convert to acetyl CoA and acetoacetyl CoA.
- Which of the following enzymes is unique to the liver? Beta-hydroxybutyrate dehydrogenase HMG-CoA lyase Thiolase 3-Ketoacyl CoA transferaseName some HMG CoA reductase inhibitors? Please answer at your own words.CHOOSE THE CORRECT LETTER 1.Which of the following enzymes catalyze the reaction involved in the production of FADHy in the Kreb's cycle?A. malate dehydrogenaseB. a-ketoglutarate dehydrogenaseC.isocitrate dehydrogenaseD. succinate dehydrogenase 2.Steric acid requires eight cycles of B-oxidation to be completely converted to acety/-CoA.A.TrueB. False
- The acyl-CoA dehydrogenase deficiency diseases are a groupof inherited defects that impair the b-oxidation of fatty acids.Symptoms of the disease range from nausea and vomiting tofrequent comas. Symptoms may be alleviated by eating regularly and avoiding periods of starvation (12 hours or more).Why does this simple procedure alleviate the symptoms?All of the following are true with respect to alpha-glucosidase inhibitor, except:A. It inhibits intestinal alpha-glucosidase B. It decreases enzymatic conversion of oligo- to monosaccharidesC. It lowers postprandial glucoseD. It causes gastrointestinal disturbances.E. It may cause development of hypertension.a man with depressive disorder is contributed in drug study that inhibit the b2 conversion to its active co-enzyme. which metabolic process is impaired in result of treatment. 1 production of Ribose 5 Phosphate from g6p. 2. Beta oxidation of palmitate to co2 3 conversion of glucose to lactate 4. breakdown of glycogen to glucose 5. synthesis of urea from alanin please explain your asnwer