If we label the two carbons composing the acetyl group of acetyl-CoA with 14C, a radioactive isotope of carbon, and this labeled acetyl-CoA enters the TCA cycle, then which CO2 released by one turn of the TCA cycle will be labeled? 1) Both. 2) Only the CO2 released by the oxidation of alpha-ketoglutarate. 3) Only the CO2 released by the oxidation of isocitrate. 4) Neither.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter19: The Tricarboxylic Acid Cycle
Section: Chapter Questions
Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...
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If we label the two carbons composing the acetyl group of acetyl-CoA with 14C, a radioactive isotope of carbon, and this labeled acetyl-CoA enters the TCA cycle, then which COreleased by one turn of the TCA cycle will be labeled?

1) Both.
2) Only the CO2 released by the oxidation of alpha-ketoglutarate.
3) Only the CO2 released by the oxidation of isocitrate.
4) Neither.
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