1. Ph NME2 H2SO4 Ph HO, Ph NM22 NME2 Ph Ph Ph Tamoxifen anti (brest) cancer drug OH2 Br 2. HBr a = Proton transfer d = Electrophilic addition g= SN1 Nucleophilic substitution b = Lewis acid/base e = El Elimination SN2 Nucleophilic substitution c = Radical chain substitution f= E2 Elimination Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. 1. 2.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution
Section16.SE: Something Extra
Problem 30MP: The carbocation electrophile in a Friede1-Crafts reaction can be generated by an alternate means...
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Ph
NME2
H2SO4
Ph
OH
Ph
`NME2
NME2
Ph
Ph
Ph
Tamoxifen
anti (brest) cancer drug
OH
OH2
Br
2.
HBr
Proton transfer
d = Electrophilic addition
g = SN1 Nucleophilic substitution
a
b
Lewis acid/base
e = El Elimination
h = SN2 Nucleophilic substitution
c =
Radical chain substitution
f= E2 Elimination
Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for
your answers.
1
2.
1.
Transcribed Image Text:Ph NME2 H2SO4 Ph OH Ph `NME2 NME2 Ph Ph Ph Tamoxifen anti (brest) cancer drug OH OH2 Br 2. HBr Proton transfer d = Electrophilic addition g = SN1 Nucleophilic substitution a b Lewis acid/base e = El Elimination h = SN2 Nucleophilic substitution c = Radical chain substitution f= E2 Elimination Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. 1 2. 1.
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