1. Two loci found in mice are suspected to be linked. To test this hypothesis, a group of graduate students performed a test cross between mice that are true breeding for both dominant traits and mice that are true breeding for both recessive traits. Individuals from the F1 generation were crossed with individuals that express both recessive traits. The phenotypic results are shown in the table below. Use chi-square analysis to determine if the graduate students’ hypothesis is supported by the evidence. Phenotype Number of Offspring Dominant 1, Recessive 2 132 Dominant 1, Dominant 2 128 Recessive 1, Recessive 2 118 Recessive 1, Dominant 2 124 a. What are the degrees of freedom and the critical chi-square value (from the table)? b. What is the calculated chi-square value? c. Do the results support that the loci are linked or that they are independently assorted (unlinked)?

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter12: Mendel, Genes, And Inheritance
Section12.2: Later Modifications And Additions To Mendel’s Principles
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1. Two loci found in mice are suspected to be linked. To test this hypothesis, a group of
graduate students performed a test cross between mice that are true breeding for both
dominant traits and mice that are true breeding for both recessive traits. Individuals from the
F1 generation were crossed with individuals that express both recessive traits. The phenotypic
results are shown in the table below. Use chi-square analysis to determine if the graduate
students’ hypothesis is supported by the evidence.


Phenotype Number of Offspring
Dominant 1, Recessive 2 132
Dominant 1, Dominant 2 128
Recessive 1, Recessive 2 118
Recessive 1, Dominant 2 124


a. What are the degrees of freedom and the critical chi-square value (from the table)?
b. What is the calculated chi-square value?
c. Do the results support that the loci are linked or that they are independently
assorted (unlinked)?

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